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Hydrocortison Produkt Beschreibung

CAS-Nr.50-23-7
Bezeichnung:Hydrocortison
Englisch Name:Hydrocortisone
Synonyma:Hydrocortison
HC;hvb;Optef;H-Cort;Hycort;Hytone;Signef;wycort;Alacort;Cleiton
CBNumber:CB9756715
Summenformel:C21H30O5
Molgewicht:362.46
MOL-Datei:50-23-7.mol
Hydrocortison physikalisch-chemischer Eigenschaften
Schmelzpunkt:: 211-214 °C(lit.)
alpha : 166 º (c=1, C2H5OH 25 ºC)
Siedepunkt:: 414.06°C (rough estimate)
Dichte: 1.0812 (rough estimate)
Brechungsindex: 1.6120 (estimate)
Flammpunkt:: 220°C
storage temp. : −20°C
Löslichkeit: H2O: 100 mg/mL
Aggregatzustand: powder
Farbe: White
Decomposition : 220 ºC
Merck : 14,4787
BRN : 1354819
Stabilität:: Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
CAS Datenbank: 50-23-7(CAS DataBase Reference)
NIST chemische Informationen: Hydrocortisone(50-23-7)
EPA chemische Informationen: Pregn-4-ene-3,20- dione, 11,17,21-trihydroxy-, (11.beta.)-(50-23-7)
Sicherheit
Kennzeichnung gefährlicher: Xn,T,F
R-Sätze:: 63-62-40-39/23/24/25-23/24/25-11
S-Sätze:: 36/37-45-36-22-16-7
RIDADR : UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany : 3
RTECS-Nr.: GM8925000
TSCA : Yes
Giftige Stoffe Daten: 50-23-7(Hazardous Substances Data)

Hydrocortison Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften
crystalline white powder
Verwenden
Principle glucocorticoid hormone produced by adrenal cortex. An anti-inflammatory hormone.
Verwenden
glucocorticoid, antiinflammatory
Verwenden
Cortisol, or Hydrocortisone, is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
Definition
ChEBI: A C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immun responses
R-Sätze Betriebsanweisung:
R63:Kann das Kind im Mutterleib möglicherweise schädigen.
R62:Kann möglicherweise die Fortpflanzungsfähigkeit beeinträchtigen.
R40:Verdacht auf krebserzeugende Wirkung.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S22:Staub nicht einatmen.
läuterung methode
Recrystallise hydrocortisone from EtOH or isoPrOH. It is bitter tasting and has UV with max at 242 nm (log 4.20). Its solubility at 25o is: H2O (0.28%), EtOH (1.5%), MeOH (0.62%), Me2CO (0.93%), CHCl3 (0.16%), propylene glycol (1.3%) and Et2O (0.35%). It gives an intense green colour with conc H2SO4. [Wendler et al. J Am Chem Soc 72 5793 1950, Beilstein 8 IV 3422.]
Hydrocortison Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Semicarbazid Isopropylacetat Kaliumtetrahydroborat Cortison-21-acetat Saponine
Downstream Produkte
11α,17,21-Trihydroxypregn-4-en-3,20-dion-21-acetat Prednisolon 17-α,21-Dihydroxypregna-4,9(11)-dien-3,20-dion-21-acetat 11β,17-Dihydroxypregna-1,4-dien-3,20-dion-17-propionat Prednison Hydrocortison-21-acetat 11β,17,21-Trihydroxypregn-4-en-3,20-dion-17-butyrat-21-propionat 6α,9-Difluor-11β,17,21-trihydroxypregna-1,4-dien-3,20-dion-17,21-di(acetat) 9-Fluor-11β,21-dihydroxypregna-1,4,16-trien-3,20-dion-21-acetat
Hydrocortison Anbieter Lieferant Produzent Hersteller Vertrieb Händler.      Global( 358)Lieferanten     
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
Hebei Guanlang Biotechnology Co., Ltd.
+86-0311-66562153 whatsapp +8615203118427
+86-0311-66562153sales@crovellbio.com CHINA 418 50
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925Abel@chembj.com CHINA 3218 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
inquiry@dakenchem.com CHINA 22144 58
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497sales01@cooperate-pharm.com CHINA 1529 55
Shanghai Bojing Chemical Co.,Ltd.
+86-21-37122233
+86-21-37127788Candy@bj-chem.com CHINA 500 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693info@tianfuchem.com CHINA 20803 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733sales@mainchem.com CHINA 32765 55
PI & PI BIOTECH INC.
020-81716320
020-81716319Sales@pipitech.com CHINA 2549 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
bruce@xrdchem.cn CHINA 511 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684info@tnjchem.com China 1428 55
 
50-23-7(Hydrocortison)Verwandte Suche:
Meprednison Cortison Prednison Prednisolon-21-(hydrogensuccinat) Prednisolon 11β,17,21-Trihydroxypregn-4-en-3,20-dion-21-(dihydrogenphosphat) Prednisolon-21-acetat 11β,17,21-Trihydroxypregn-4-en-3,20-dion-21-pivalat 11β,17,21-Trihydroxypregn-4-en-3,20-dion-21-(3,3-dimethylbutyrat) Hydrocortison Hydrocortison-21-(hydrogensuccinat) Fludroxycortid Pregn-4-en-3,20-dion, 11,17-Dihydroxy-21-(phosphonooxy)-, Dinatriumsalz, (11β)- 11β,17,21-Trihydroxypregn-4-en-3,20-dion-21-octanoat 11β,17,21-Trihydroxypregn-4-en-3,20-dion-21-cyclopentanpropionat Hydrocortison-21-(natriumsuccinat) Diethylstilbestrol Hydrocortison-21-acetat
11,17a,21-Trihydroxy-4-pragnene-3,20-dione 11-beta,17,21-trihydroxypregn-4-ene-3,20-dione 11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 11-beta,17-alpha,21-trihydroxy-4-pregnene-3,20-dione 11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione 11-beta,17-alpha-trihydroxypregnane-4-ene-3,20-dione 11-beta-hydrocortisone 11beta-Hydrocortisone 11-beta-hydroxycortisone 11beta-Hydroxycortisone 17,21-trihydroxy-20-dion(11-beta)-pregn-4-ene-11 17,21-trihydroxy-20-dion(11beta)-pregn-4-ene-11 17a-Hydroxycorticosterone Acticort Aeroseb-HC Alacort ala-cort Ala-Scalp Alphaderm anti-Inflammatory hormone anti-inflammatoryhormone Barseb HC barsebhc CaldeCORT Spray Cetacort Cleiton Cobadex component of Cor-tar-quin component of Cort-quin cortisporin component of Drotic component of Lubricort component of Neo-Cort-Dome component of Nystaform-hc component of Otalgine component of Otic-neo-cort-dome component of Otobiotic component of Otocort component of Pediotic suspens Compound F Compound F (kendall) compoundf(kendall) Cortanal Cort-Dome Cortenema Corticreme Cortifan Cortiment Cortisol alcohol cortisolalcohol Cortispray Cortolotion Cortonema Cortoxide Cortril Cremesone Delacort demacort Dermacort
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