ChemicalBook >> CAS DataBase List >>Ldn193189
Ldn193189
- CAS No.
- 1062368-24-4
- Chemical Name:
- Ldn193189
- Synonyms
- LDN193189;CS-205;DM-3189;DM 3189;LDN193189(DM3189);LDN-193189, >=98%;LDN193189 free base;LDN-193189;LDN 193189;LDN193189 LDN193189 HCl;LDN-193189;LDN 193189;DM-3189;DM 3189
- CBNumber:
- CB00123694
- Molecular Formula:
- C25H22N6
- Molecular Weight:
- 406.48
- MDL Number:
- MFCD17169988
- MOL File:
- 1062368-24-4.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:16
| Density | 1.33 |
|---|---|
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | H2O: soluble5mg/mL, clear (warmed) |
| form | powder |
| pka | 8.79±0.10(Predicted) |
| color | yellow to orange |
| InChIKey | XHBVYDAKJHETMP-UHFFFAOYSA-N |
| FDA UNII | W69H5YQU9O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | 3 |
| HS Code | 29339900 |
Ldn193189 price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0559 | LDN193189 hydrochloride ≥98% (HPLC) | 1062368-24-4 | 5mg | $130 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0559 | LDN193189 hydrochloride ≥98% (HPLC) | 1062368-24-4 | 25mg | $522 | 2024-03-01 | Buy |
| Cayman Chemical | 11802 | LDN-193189 ≥95% | 1062368-24-4 | 1mg | $35 | 2024-03-01 | Buy |
| Cayman Chemical | 11802 | LDN-193189 ≥95% | 1062368-24-4 | 5mg | $96 | 2024-03-01 | Buy |
| Cayman Chemical | 11802 | LDN-193189 ≥95% | 1062368-24-4 | 10mg | $140 | 2024-03-01 | Buy |
Ldn193189 Chemical Properties,Uses,Production
Biological Activity
LDN-193189 is a selective BMP signaling inhibitor, inhibits the ALK1, ALK2, ALK3 and ALK6 with IC50s of 0.8 nM, 0.8 nM, 5.3 nM and 16.7 nM in the kinase assay, respectively. LDN-193189 inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50s of 5 nM and 30 nM in C2C12 cells, respectively, exhibits 200-fold selectivity for BMP versus TGF-β. For animal testing, the water-soluble S7507 LDN-193189 2HCl is recommended.
Ldn193189 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 155)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29067 | 58 |
View Lastest Price from Ldn193189 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-08-21 | Sodium tetraborate pentahydrate
12179-04-3
|
1kg | 99% | 100tons | Anhui Ruihan Technology Co., Ltd |
-
- Sodium tetraborate pentahydrate
12179-04-3
- 99%
- Anhui Ruihan Technology Co., Ltd
1062368-24-4(Ldn193189)Related Search:
LDN193189
LDN193189 HCl
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LDN193189(DM3189)
4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
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LDN 193189 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
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LDN-193189, >=98%
6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine USP/EP/BP
Quinoline, 4-[6-[4-(1-piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-
LDN-193189, 98%, a selective BMP signaling inhibitor
LDN193189 free base
CS-205
LDN-193189;LDN 193189
LDN-193189;LDN 193189;DM-3189;DM 3189
LDN193189
1062368-24-4
C25H22N6
Smad
TGF-beta
Inhibitors
TGF-beta/Smad