1,1'-Thiocarbonyldiimidazole
- CAS No.
- 6160-65-2
- Chemical Name:
- 1,1'-Thiocarbonyldiimidazole
- Synonyms
- TCDI;Di(1H-imidazol-1-yl)methanethione;1,1-THIOCARBONYLDIIMIDAZOLE;Thiocarbonyl diimidazole;bis(1H-imidazol-2-yl)methanethione;DiiMidaz;diimidazoL;1,1'-THIOCARBONYL;1,1'-Thiocarbonyldii;Thiocarbonylbisimidazole
- CBNumber:
- CB0280138
- Molecular Formula:
- C7H6N4S
- Molecular Weight:
- 178.21
- MDL Number:
- MFCD00005289
- MOL File:
- 6160-65-2.mol
- MSDS File:
- SDS
Melting point | 98-102 °C(lit.) |
---|---|
Boiling point | 342°C (rough estimate) |
Density | 1.3046 (rough estimate) |
refractive index | 1.5500 (estimate) |
storage temp. | 2-8°C |
solubility | Soluble in terahydrofuran, toluene and dichloromethane. |
pka | 1.96±0.10(Predicted) |
form | Powder |
color | Bright yellow |
Water Solubility | decomposes |
Sensitive | Moisture Sensitive |
BRN | 609349 |
Stability | Stable, but air and moisture sensitive. Incompatible with strong oxidizing agents, strong acids. |
InChIKey | RAFNCPHFRHZCPS-UHFFFAOYSA-N |
CAS DataBase Reference | 6160-65-2(CAS DataBase Reference) |
FDA UNII | H8A75XB5AY |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 22-34 | |||||||||
Safety Statements | 22-24/25-45-36/37/39-26 | |||||||||
WGK Germany | 3 | |||||||||
F | 9-21 | |||||||||
Hazard Note | Irritant/Keep Cold/Moisture Sensitive | |||||||||
HS Code | 29332900 | |||||||||
NFPA 704 |
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1,1'-Thiocarbonyldiimidazole price More Price(36)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 156051 | 1,1′-Thiocarbonyldiimidazole technical grade, 90% | 6160-65-2 | 5g | $58.3 | 2024-03-01 | Buy |
Sigma-Aldrich | 156051 | 1,1′-Thiocarbonyldiimidazole technical grade, 90% | 6160-65-2 | 10g | $110 | 2024-03-01 | Buy |
TCI Chemical | C1376 | 1,1'-Thiocarbonyldiimidazole >95.0%(GC)(T) | 6160-65-2 | 5g | $146 | 2024-03-01 | Buy |
TCI Chemical | C1376 | 1,1'-Thiocarbonyldiimidazole >95.0%(GC)(T) | 6160-65-2 | 25g | $508 | 2024-03-01 | Buy |
Alfa Aesar | B22008 | 1,1'-Thiocarbonyldiimidazole, tech 90% | 6160-65-2 | 10g | $105 | 2024-03-01 | Buy |
1,1'-Thiocarbonyldiimidazole Chemical Properties,Uses,Production
Chemical Properties
yellow powder
Application
1,1′-Thiocarbonyldiimidazole (TCDI) is generally used as a reagent to carry out the deoxygenation of vicinal diols by forming cyclic thionocarbonate in Corey-Winter alkene synthesis.
It is used as a reagent in the enantioselective total synthesis of (+)-hapalindole Q, 12-epi-fischerindole U and welwitindolinone A.
It is also used in the preparation of trithiocarbonates, xanthates, and dithiocarbamates as chain transfer agents for the reversible addition fragmentation chain transfer and macromolecular design (RAFT/ MADIX) polymerization.
Uses
1,1’Thiocarbonyldiimidazole can be used to deoxygenate carboxylic monosaccharide analogues.
Uses
1,1'-Thiocarbonyldiimidazole is used as a reagent for the deoxygenation of alcohols with tributyltin hydride and diols with lithium aluminum hydride. It is also used to deoxygenate carboxylic monosaccharide analogues. Further, it is a useful reagent involved in biochemical synthesis. In addition to this, it is used to prepare 1-[bis-(4-methoxy-phenyl)-methyl]-1H-imidazole by reacting with 4,4'-dimethoxy-benzhydrol.
Synthesis Reference(s)
The Journal of Organic Chemistry, 43, p. 337, 1978 DOI: 10.1021/jo00396a035
Purification Methods
It forms yellow crystals on recrystallisation from tetrahydrofuran or by sublimation at 10-3torr (bath temperature 70-80o). It is hydrolysed by H2O and should be stored dry. [Staab & Walther Justus Liebigs Ann Chem 657 98 1962; Pullukat et al. Tetrahedron Lett 1953 1967, Hanessian et al. Can J Chem 65 1859 1987, Rajanbabu et al. J Am Chem Soc 111 1759 1989.] Thiochrome {2,7-dimethyl-5H -thiachromine-8-ethanol; 3,8-dimethyl-2-hydroxyethyl-5H -
1,1'-Thiocarbonyldiimidazole Preparation Products And Raw materials
Raw materials
Preparation Products
1of4
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 20356 | 58 |
CHANGZHOU HARVECHEM LTD | +86-0519-88784888 +8613906120163 | inquiry@harvechem.com | China | 245 | 58 |
Shanghai Famo Biotech Co Ltd | +8618550473860 | mayan@famobiotech.com | China | 509 | 58 |
Hebei Duling International Trade Co. LTD | +8617333973358 | sales01@hbduling.cn | China | 15547 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16224 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21687 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9338 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32715 | 60 |
Zjartschem | +86-571-8723 8903 jocelynpan@zjarts.com | jocelynpan@zjarts.com | CHINA | 993 | 58 |
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View Lastest Price from 1,1'-Thiocarbonyldiimidazole manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-05-29 | 1,1'-Thiocarbonyldiimidazole
6160-65-2
|
US $10.00 / kg | 1kg | 99% | 100 Ton | Hebei Duling International Trade Co. LTD | ||
2023-09-06 | 1,1'-Thiocarbonyldiimidazole
6160-65-2
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. | ||
2023-03-06 | Thiocarbonyldiimidazole
6160-65-2
|
US $2.00 / Kg/Bag | 10g | 99% | 10000kg | Hebei Guanlang Biotechnology Co,.LTD |
- 1,1'-Thiocarbonyldiimidazole
6160-65-2
- US $10.00 / kg
- 99%
- Hebei Duling International Trade Co. LTD
- 1,1'-Thiocarbonyldiimidazole
6160-65-2
- US $0.00-0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
- Thiocarbonyldiimidazole
6160-65-2
- US $2.00 / Kg/Bag
- 99%
- Hebei Guanlang Biotechnology Co,.LTD