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1-(2-THIAZOLYLAZO)-2-NAPHTHOL

1-(2-THIAZOLYLAZO)-2-NAPHTHOL structure

CAS No.: 1147-56-4

Chemical Name:: 1-(2-THIAZOLYLAZO)-2-NAPHTHOL

Synonyms: TAN;ERGi-USU;NSC139021;Nitrilotantalum(III);NSC139021 (ERGi-USU);ERGi-USU (NSC139021);1-(2’-Thiazolylazo)-β-naphtho;1-(2-THIAZOLYLAZO)-2-NAPHTHOL;1-(thiazol-2-ylazo)-2-naphthol;1-(2'-Thiazolylazo)-β-naphthol

CBNumber:: CB0321974

Molecular Formula:: C13H9N3OS

Molecular Weight:: 255.3

MDL Number:: MFCD00021611

MOL File:: 1147-56-4.mol

MSDS File:: SDS

Last updated:2023-06-30 15:45:59

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1-(2-THIAZOLYLAZO)-2-NAPHTHOL Properties

Melting point	138-139 °C
Boiling point	464.8±47.0 °C(Predicted)
Density	1.40
storage temp.	2-8°C
solubility	methanol: 10 mg/mL, clear
pka	8.71±0.50(Predicted)
form	solid
color	Red or orange
BRN	223783
Stability	Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
CAS DataBase Reference	1147-56-4(CAS DataBase Reference)
EPA Substance Registry System	2-Naphthalenol, 1-(2-thiazolylazo)- (1147-56-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Risk Statements

36/37/38

Safety Statements

22-24/25

WGK Germany

TSCA

Yes

HS Code

2927.00.5000

NFPA 704

	1
2		0

1-(2-THIAZOLYLAZO)-2-NAPHTHOL price More Price(18)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	A5003	TAN [=1-(2-Thiazolylazo)-2-naphthol][Spectrophotometric reagent for transition metals] >99.0%(T)	1147-56-4	1g	$72	2024-03-01	Buy
TCI Chemical	A5003	TAN [=1-(2-Thiazolylazo)-2-naphthol][Spectrophotometric reagent for transition metals] >99.0%(T)	1147-56-4	5g	$246	2024-03-01	Buy
Alfa Aesar	B24011	1-(2-Thiazolylazo)-2-naphthol, 98%	1147-56-4	1g	$32.65	2024-03-01	Buy
Alfa Aesar	B24011	1-(2-Thiazolylazo)-2-naphthol, 98%	1147-56-4	5g	$103.65	2024-03-01	Buy
Alfa Aesar	B24011	1-(2-Thiazolylazo)-2-naphthol, 98%	1147-56-4	25g	$409.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
A5003	1g	$72	Buy
A5003	5g	$246	Buy
B24011	1g	$32.65	Buy
B24011	5g	$103.65	Buy
B24011	25g	$409.65	Buy

1-(2-THIAZOLYLAZO)-2-NAPHTHOL Chemical Properties,Uses,Production

Description

ERGi-USU (1147-56-4) selectively inhibits the growth of ERG-positive VCaP prostate cancer cells, COLO320 colon cancer cells, KG-1 and MOLT-4 leukemia cells with minimal effect on ERG-negative cells or normal prostate or endothelial cells (IC50 = 169 nM for cell growth and 315 nM for ERG protein in VCaP cells). It selectively inhibits the kinase RIOK2 (Kd = 200 nM) causing disruption of ribosomal biogenesis and ribosomal stress.

Uses

1-(2-Thiazolylazo)-2-naphthol is a high affinity Rio Kinase 2 (RIOK2) inhibitor (Kd = 200 nM). Exhibits >6-fold selectivity for RIOK2 over a panel of 456 kinases. Inhibits ERG protein and potently inhibits growth of ERG-positive VCaP prostate cancer cells in vitro (IC50 = 169 nM) but not ERG-negative cell lines. Also inhibits growth of VCaP xenografts in mice.

storage

Store at +4°C

References

1) Mohamed et al. (2018), Identification of a Small Molecule That Selectively Inhibits ERG-Positive Cancer Cell Growth; Cancer Res. 78 3659

1-(2-THIAZOLYLAZO)-2-NAPHTHOL Preparation Products And Raw materials

Raw materials

Preparation Products

1-(2-THIAZOLYLAZO)-2-NAPHTHOL Suppliers

Global( 84)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503259 +86-19930503259	cherry@crovellbio.com	China	18456	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58

Supplier	Advantage
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
InvivoChem	58
Hebei Guanlang Biotechnology Co., Ltd.	58
TargetMol Chemicals Inc.	58
LEAPCHEM CO., LTD.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58

View Lastest Price from 1-(2-THIAZOLYLAZO)-2-NAPHTHOL manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2021-08-12	1-(2-THIAZOLYLAZO)-2-NAPHTHOL 1147-56-4	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2021-07-02	TAN [=1-(2-Thiazolylazo)-2-naphthol][Spectrophotometric reagent for transition metals] 1147-56-4	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2020-01-09	1-(2-THIAZOLYLAZO)-2-NAPHTHOL 1147-56-4	US $1.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

1-(2-THIAZOLYLAZO)-2-NAPHTHOL
1147-56-4
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

TAN [=1-(2-Thiazolylazo)-2-naphthol][Spectrophotometric reagent for transition metals]
1147-56-4
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

1-(2-THIAZOLYLAZO)-2-NAPHTHOL
1147-56-4
US $1.00 / KG
99%
Career Henan Chemical Co

1-(2-THIAZOLYLAZO)-2-NAPHTHOL Spectrum

1-(2-THIAZOLYLAZO)-2-NAPHTHOL(1147-56-4)MS 1-(2-THIAZOLYLAZO)-2-NAPHTHOL(1147-56-4)¹HNMR 1-(2-THIAZOLYLAZO)-2-NAPHTHOL(1147-56-4)¹³CNMR 1-(2-THIAZOLYLAZO)-2-NAPHTHOL(1147-56-4)IR1 1-(2-THIAZOLYLAZO)-2-NAPHTHOL(1147-56-4)IR2

1147-56-4(1-(2-THIAZOLYLAZO)-2-NAPHTHOL)Related Search:

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TPPS 1-[4-(1-Adamantyl)-2-thiazolylazo]-2-naphthol 1-(2-THIAZOLYLAZO)-2-NAPHTHOL

1of2

TAN 2-(2-Hydroxy-1-naphthylazo)thiazole, TAN Nitrilotantalum(III) 1-(Thiazole-2-ylazo)-2-naphthol 1-(Thiazole-2-ylazo)naphthalene-2-ol 1-[(Thiazole-2-yl)azo]-2-naphthol TAN [=1-(2-Thiazolylazo)-2-naphthol] TAN [=1-(2-Thiazolylazo)-2-naphthol] [Spectrophotometric reagent for transition metals] (E)-1-(thiazol-2-yldiazenyl)naphthalen-2-ol 1-(2-Thiazolylazo)-2-naphthol,2-(2-Hydroxy-1-naphthylazo)thiazole, TAN 1-(1,3-Thiazolyl-2-azo)-2-naphthol 1-(2’-Thiazolylazo)-β-naphtho 1-(2-thiazolylazo)-2-naphthaleno 1-(2-thiazolylazo)-2-Naphthalenol 2-(2-HYDROXY-1-NAPHTHYLAZO)THIAZOLE 1-(2-THIAZOLYLAZO)-2-NAPHTHOL 1-(thiazol-2-ylazo)-2-naphthol 1-(2'-Thiazolylazo)-β-naphthol NSC139021 (ERGi-USU) 2-Naphthalenol, 1-[2-(2-thiazolyl)diazenyl]- TAN [=1-(2-Thiazolylazo)-2-naphthol][Spectrophotometric reagent for transition metals]> NSC139021 ERGi-USU (NSC139021) (1Z)-1-(2-thiazolylhydrazinylidene)-2-naphthalenone 1-[2-(2-Thiazolyl)diazenyl]-2-naphthalenol ERGi-USU inhibit,NSC 139021,NSC-139021,NSC139021,Inhibitor 1147-56-4 147-56-4 IR/UV/ VIS Analytical Chromatography Product Catalog Analytical Reagents Azo Compounds Naphthylazo Compounds Chelating Reagents Spectroscopy Reagents Analytical Chemistry Azo Compounds Chelating Reagents Naphthylazo Compounds