CHOLINE THIEOPHYLLINATE
- CAS No.
- 4499-40-5
- Chemical Name:
- CHOLINE THIEOPHYLLINATE
- Synonyms
- Teovent;Sabidal;filoral;Zy-15061;teokolin;choledyl;cholegyl;Sabidal SR;Bronchodil;theoxylline
- CBNumber:
- CB1441097
- Molecular Formula:
- C12H21N5O3
- Molecular Weight:
- 283.33
- MDL Number:
- MFCD00236001
- MOL File:
- 4499-40-5.mol
| Melting point | 176-178 °C |
|---|---|
| storage temp. | Store at -20°C |
| solubility | PBS (pH 7.2): 10 mg/ml |
| form | A crystalline solid |
| FDA UNII | 3K045XR58X |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P301+P312+P330 | |||||||||
| HS Code | 2939590000 | |||||||||
| NFPA 704 |
|
CHOLINE THIEOPHYLLINATE price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1484009 | Oxtriphylline | 4499-40-5 | 500mg | $250 | 2024-03-01 | Buy |
| Cayman Chemical | 24006 | Oxtriphylline ≥98% | 4499-40-5 | 50mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 24006 | Oxtriphylline ≥98% | 4499-40-5 | 100mg | $108 | 2024-03-01 | Buy |
| Cayman Chemical | 24006 | Oxtriphylline ≥98% | 4499-40-5 | 500mg | $505 | 2024-03-01 | Buy |
| TRC | O867275 | Oxytrimethylline | 4499-40-5 | 500mg | $160 | 2021-12-16 | Buy |
CHOLINE THIEOPHYLLINATE Chemical Properties,Uses,Production
Originator
Sabidal ,S.R. Zyma, UK ,1983
Uses
Oxytrimethylline is used in the treatment for chronic asthma.
Uses
Bronchodilator.
Manufacturing Process
18 parts by weight of theophylline are added to 37.8 parts by weight of aqueous choline bicarbonate (47% assay) and the mixture stirred and heated at 80°C to 90°C until the evolution of carbon dioxide has ceased and complete solution effected. Water is separated from the reaction mixture by distillation under a vacuum sufficient to keep the still temperature between 50°C and 55 C. After about 95 parts by weight of water have been separated, about 80 parts by weight of isopropyl alcohol are added and the mixture subjected to further distillation under a vacuum sufficient to keep the mixture boiling at about 40°C. The distillation removes some of the water as an azeotrope with the isopropyl alcohol. During the removal of the water-isopropyl alcohol azeotrope a crystalline precipitate forms. The mixture is further cooled slowly to 5°C and the crystalline precipitate filtered off. The choline theophyllinate crystals are then washed with isopropyl alcohol and dried under vacuum at about 70°C. A second crop of the product may be obtained from the mother liquor by further reduction in volume and cooling. A yield of 90.5% of theory of choline theophyllinate is obtained completely free of inorganic salts.
brand name
Choledyl(Parke-Davis).
Therapeutic Function
Smooth muscle relaxant
CHOLINE THIEOPHYLLINATE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 18192627656 | 1012@dideu.com | China | 3422 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Qiuxian Baitai New Material Co., LTD | +8618330912755 | sale2@hbyalin.com | China | 1677 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29220 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
View Lastest Price from CHOLINE THIEOPHYLLINATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-11-27 | CHOLINE THIEOPHYLLINATE
4499-40-5
|
US $8.00 / g | 1KG | 99% | 5ton/Month | Qiuxian Baitai New Material Co., LTD | |
 |
2021-05-29 | CHOLINE THIEOPHYLLINATE USP/EP/BP
4499-40-5
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2020-04-25 | Choline theophyllinate
4499-40-5
|
US $0.01-1.00 / KG | 1KG | 99% | 50 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- CHOLINE THIEOPHYLLINATE
4499-40-5
- US $8.00 / g
- 99%
- Qiuxian Baitai New Material Co., LTD
-
- CHOLINE THIEOPHYLLINATE USP/EP/BP
4499-40-5
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- Choline theophyllinate
4499-40-5
- US $0.01-1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd