Tandutinib
- CAS No.
- 387867-13-2
- Chemical Name:
- Tandutinib
- Synonyms
- CS-309;MLN 518;CT 53518;NSC726292;Tandutinib;Unii-E1io3icj9a;CT53518; MLN518;Tandutinib(TINIBS);MLN518, Tandutinib;Tandutinib (MLN518)
- CBNumber:
- CB31011758
- Molecular Formula:
- C31H42N6O4
- Molecular Weight:
- 562.7
- MDL Number:
- MFCD09954147
- MOL File:
- 387867-13-2.mol
Melting point | 177-178°C |
---|---|
Boiling point | 769.5±60.0 °C(Predicted) |
Density | 1.213±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,Store in freezer, under -20°C |
solubility | Chloroform (Slightly), Methanol (Slightly) |
form | Solid |
pka | 13.39±0.70(Predicted) |
color | White to Off-White |
CAS DataBase Reference | 387867-13-2(CAS DataBase Reference) |
NCI Dictionary of Cancer Terms | CT53518; MLN518; tandutinib |
FDA UNII | E1IO3ICJ9A |
NCI Drug Dictionary | tandutinib |
Tandutinib price More Price(31)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SML2672 | Tandutinib hydrochloride ≥98% (HPLC) | 387867-13-2 | 25MG | $60.7 | 2024-03-01 | Buy |
Sigma-Aldrich | SML2672 | Tandutinib hydrochloride ≥98% (HPLC) | 387867-13-2 | 100MG | $98.4 | 2024-03-01 | Buy |
Cayman Chemical | 12098 | Tandutinib ≥95% | 387867-13-2 | 25mg | $56 | 2024-03-01 | Buy |
Cayman Chemical | 12098 | Tandutinib ≥95% | 387867-13-2 | 50mg | $93 | 2024-03-01 | Buy |
Cayman Chemical | 12098 | Tandutinib ≥95% | 387867-13-2 | 100mg | $140 | 2024-03-01 | Buy |
Tandutinib Chemical Properties,Uses,Production
Description
Tandutinib is a potent antagonist of platelet-
Chemical Properties
White Solid
Uses
An oral, small-molecule inhibitor of FLT3 for the treatment of AML (acute myelogenous leukemia) clinical trials in patients with AML and myelodysplastic syndrome, but displayed promising antileukemic activity (90% complete remissions) in a phase I/II trial in patients with newly diagnosed AML w hen administered in combination with cytarabine and daunorubicin.
Uses
An oral, small-molecule inhibitor of FLT3 for the treatment of AML (acute myelogenous leukemia) and other cancer indications. The drug exhibited limited activity as a single agent in phase I and II clinical trials in patients with AML and myelody
Uses
antipsoratic
Definition
ChEBI: An N-arylpiperazine that is piperazine in which the hydrogen attached to the nitrogen at position 1 is replaced by a 6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-yl group, while the hydrogen attached to the nitrogen at position 4 s replaced by a (p-isopropoxyphenyl)aminocarbonyl group. Tandutinib is an inhibitor of tyrosine kinases FLT3, PDGFR and KIT.
target
c-Kit
References
[1] kelly lm1, yu jc, boulton cl, apatira m, li j, sullivan cm, williams i, amaral sm, curley dp, duclos n, neuberg d, scarborough rm, pandey a, hollenbach s, abe k, lokker na, gilliland dg, giese na. ct53518, a novel selective flt3 antagonist for the treatment of acute myelogenous leukemia (aml). cancer cell. 2002 jun;1(5):421-32.
Tandutinib Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 | xie@china-sinoway.com | China | 988 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29822 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23555 | 58 |
View Lastest Price from Tandutinib manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-23 | Tandutinib
387867-13-2
|
US $0.00-0.00 / kg | 1kg | 99% | 20tons | Sinoway Industrial co., ltd. | ||
2022-02-25 | Tandutinib
387867-13-2
|
US $2.00 / KG | 1KG | 98% | 100KG | Hong Kong Tiansheng New Material Trading Co., Ltd | ||
2022-02-25 | Tandutinib
387867-13-2
|
US $2.00 / KG | 1KG | 99% | 10kg | Hong Kong Tiansheng New Material Trading Co., Ltd |
- Tandutinib
387867-13-2
- US $0.00-0.00 / kg
- 99%
- Sinoway Industrial co., ltd.
- Tandutinib
387867-13-2
- US $2.00 / KG
- 98%
- Hong Kong Tiansheng New Material Trading Co., Ltd
- Tandutinib
387867-13-2
- US $2.00 / KG
- 99%
- Hong Kong Tiansheng New Material Trading Co., Ltd