ChemicalBook >> CAS DataBase List >>Tubacin
Tubacin
- CAS No.
- 537049-40-4
- Chemical Name:
- Tubacin
- Synonyms
- Tubacin;BML-GR362;4R,6S)N8-[(2R,dioxan-Tubacin, >=98%;diphenyl-oxazolyl)
- CBNumber:
- CB32519138
- Molecular Formula:
- C41H43N3O7S
- Molecular Weight:
- 721.86
- MDL Number:
- MFCD18452824
- MOL File:
- 537049-40-4.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:21
| Melting point | 155 - 157°C |
|---|---|
| storage temp. | -20°C |
| solubility | DMSO: ≥10mg/mL |
| form | powder |
| color | white to tan |
| FDA UNII | 02C2G1D30D |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| WGK Germany | 3 |
Tubacin price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0065 | Tubacin ≥98% (HPLC) | 537049-40-4 | 1mg | $239 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0065 | Tubacin ≥98% (HPLC) | 537049-40-4 | 5mg | $631 | 2024-03-01 | Buy |
| Cayman Chemical | 13691 | Tubacin ≥90% | 537049-40-4 | 1mg | $106 | 2024-03-01 | Buy |
| Cayman Chemical | 13691 | Tubacin ≥90% | 537049-40-4 | 5mg | $336 | 2024-03-01 | Buy |
| Tocris | 3402 | Tubacin ≥96%(HPLC) | 537049-40-4 | 1 | $287 | 2021-12-16 | Buy |
Tubacin Chemical Properties,Uses,Production
Uses
Tubacin is tubulin acetylation inducer that selectively inhibits histone deacetylase (HDAC6).
Definition
ChEBI: N-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N'-hydroxyoctanediamide is a member of 1,3-oxazoles.
Biochem/physiol Actions
Tubacin triggers the release of reactive oxygen species and mediates caspase-3-independent apoptosis of Epstein-Barr virus (EBV)-positive Burkitt lymphoma cells. It suppresses the proliferation of acute lymphoblastic leukemia (ALL) cells and enhances the effect of chemotherapy to treat ALL cells. Tubacin prevents the epileptic activity and neuronal migration defects caused due to lowered expression of Srpx2 in rats.
target
HDAC6
Tubacin Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 84)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 20000 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
537049-40-4(Tubacin)Related Search:
Tubacin
N1-(4-((2R,4R,6S)-4-((4,5-diphenyloxazol-2-ylthio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-dioxan-2-yl)phenyl)-N8-hydroxyoctanediamide
N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide Tubacin
N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-octanediamide
Tubacin, >=98%
N1-(4-((2R,4R,6S)-4-(((4,5-Diphenyloxazol-2-yl)thio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-di
BML-GR362
Tubacin (BML-GR362)
Octanediamide, N1-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N8-hydroxy-, rel-
Octanediamide,N-[4-[(2R,4R,6S)-4-[[(4,5-diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N'-hydroxy-, rel-
Tubacin (tubulin acetylation inducer)
rel-N1-(4-((2R,4R,6S)-4-(((4,5-Diphenyloxazol-2-yl)thio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-dioxan-2-yl)phenyl)-N8-hydroxyoctanediamide
Tubacin,Inhibitor,HDAC,Virus Protease,inhibit,Histone deacetylases
(hydroxymethyl)
[(2R,
4R,
6S)
dioxan-
diphenyl-
N8-
Octanediamide, N1-
oxazolyl)
537049-40-4
C41H43N3O7S
Inhibitors