OXAMFLATIN
- CAS No.
- 151720-43-3
- Chemical Name:
- OXAMFLATIN
- Synonyms
- CS-2473;Metacept 3;METACEPT 3;OXAMFLATIN;Oxamflatin (Metacept-3);(E)-N-hydroxy-5-(3-(phenylsulfonaMido)phenyl)pent-2-en-4-ynaMide;(2E)-N-Hydroxy-5-[3-[(Phenylsulfonyl)Amino]Phenyl]-2-Penten-4-Ynamide;2-Penten-4-ynamide, N-hydroxy-5-[3-[(phenylsulfonyl)amino]phenyl]-, (2E)-
- CBNumber:
- CB3504059
- Molecular Formula:
- C17H14N2O4S
- Molecular Weight:
- 342.37
- MDL Number:
- MFCD00949087
- MOL File:
- 151720-43-3.mol
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 |
|---|---|
| WGK Germany | 3 |
OXAMFLATIN price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | O3139 | Oxamflatin ≥98% (HPLC), solid | 151720-43-3 | 1mg | $187 | 2024-03-01 | Buy |
| Sigma-Aldrich | O3139 | Oxamflatin ≥98% (HPLC), solid | 151720-43-3 | 5mg | $656 | 2024-03-01 | Buy |
| Cayman Chemical | 13176 | Oxamflatin ≥95% | 151720-43-3 | 1mg | $77 | 2024-03-01 | Buy |
| Cayman Chemical | 13176 | Oxamflatin ≥95% | 151720-43-3 | 5mg | $340 | 2024-03-01 | Buy |
| Cayman Chemical | 13176 | Oxamflatin ≥95% | 151720-43-3 | 10mg | $602 | 2024-03-01 | Buy |
OXAMFLATIN Chemical Properties,Uses,Production
Chemical Properties
Red-Brown Solid
Uses
Histone deacetylase inhibitor. A cell-permeable, aromatic sulfonamide derivative with a hydroxamic acid group that potently inhibits mammalian HDAC by binding to the active site zinc.
Definition
ChEBI: 5-[3-(benzenesulfonamido)phenyl]-N-hydroxypent-2-en-4-ynamide is a sulfonamide.
Enzyme inhibitor
This anti-tumor agent (FW = 342.38 g/mol; CAS 151720-43-3; Solubility: 13 mg/mL DMSO, methanol, acetonitrile, 10 mg/mL), also known as (2E)- 5-[3-[(phenylsulfonyl)amino]phenyl]-pent-2-en-4-ynohydroxamate, inhibits histone deacetylase. Oxamflatin shows antiproliferative activity in vitro against various mouse and human tumor cell lines, attended by drastic changes in the cell morphology and in vivo antitumor activity against B16 melanoma. Oxamflatin causes an elongated cell shape with filamentous protrusions as well as arrest of the cell cycle at the G1 phase in HeLa cells. These phenotypic changes in HeLa cells were similar to those induced by trichostatin A (TSA), a specific inhibitor of histone deacetylase (HDAC).
OXAMFLATIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9340 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32715 | 60 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| Hong Kong Tiansheng New Material Trading Co., Ltd | +8617320695765 | zxx@hktiansheng.com | China | 981 | 58 |
| Hebei Duling International Trade Co. LTD | +8617333973358 | sales01@hbduling.cn | China | 15620 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 6010 | 61 |
View Lastest Price from OXAMFLATIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-02-25 | Oxamflatin
151720-43-3
|
US $100.00 / KG | 1KG | 98% | 100KG | Hong Kong Tiansheng New Material Trading Co., Ltd | |
 |
2022-02-25 | Oxamflatin
151720-43-3
|
US $100.00 / Kg/Bag | 1KG | 99% | 10kg | Hong Kong Tiansheng New Material Trading Co., Ltd | |
 |
2019-12-27 | OXAMFLATIN
151720-43-3
|
US $1.00 / KG | 1KG | 97%-99.9% | 100kg | Career Henan Chemical Co |
-
- Oxamflatin
151720-43-3
- US $100.00 / KG
- 98%
- Hong Kong Tiansheng New Material Trading Co., Ltd
-
- Oxamflatin
151720-43-3
- US $100.00 / Kg/Bag
- 99%
- Hong Kong Tiansheng New Material Trading Co., Ltd
-
- OXAMFLATIN
151720-43-3
- US $1.00 / KG
- 97%-99.9%
- Career Henan Chemical Co