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6-Chloro-1H-indole-2-carbaldehyde

6-Chloro-1H-indole-2-carbaldehyde Structure
6-Chloro-1H-indole-2-carbaldehyde structure
CAS No.
53590-59-3
Chemical Name:
6-Chloro-1H-indole-2-carbaldehyde
Synonyms
6-Chloro-1H-indole-2-carbaldehyde;1H-Indole-2-carboxaldehyde, 6-chloro-
CBNumber:
CB42455352
Molecular Formula:
C9H6ClNO
Molecular Weight:
179.6
MDL Number:
MFCD11040767
MOL File:
53590-59-3.mol
MSDS File:
SDS
Last updated:2026-09-12 18:52:40
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6-Chloro-1H-indole-2-carbaldehyde Properties

Boiling point 373.4±22.0 °C(Predicted)
Density 1.431±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 14.15±0.30(Predicted)
Appearance Light yellow to brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
HS Code  29339900

6-Chloro-1H-indole-2-carbaldehyde price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR927744 6-Chloro-1H-indole-2-carbaldehyde 97% 53590-59-3 100mg $29 2026-06-04 Buy
Apolloscientific OR927744 6-Chloro-1H-indole-2-carbaldehyde 97% 53590-59-3 250mg $45 2026-06-04 Buy
Apolloscientific OR927744 6-Chloro-1H-indole-2-carbaldehyde 97% 53590-59-3 1g $74 2026-06-04 Buy
Apolloscientific OR927744 6-Chloro-1H-indole-2-carbaldehyde 97% 53590-59-3 5g $294 2026-06-04 Buy
aablocks AA00DCKA 6-Chloro-1H-indole-2-carbaldehyde ≥97% 53590-59-3 100mg $18 2026-05-28 Buy
Product number Packaging Price Buy
OR927744 100mg $29 Buy
OR927744 250mg $45 Buy
OR927744 1g $74 Buy
OR927744 5g $294 Buy
AA00DCKA 100mg $18 Buy

6-Chloro-1H-indole-2-carbaldehyde Chemical Properties, Uses, Production

Chemical Properties

Brown solid

Synthesis

(6-CHLORO-1H-INDOL-2-YL)-METHANOL

53590-58-2

6-CHLORO-1H-INDOLE-2-CARBALDEHYDE

53590-59-3

GENERAL STEPS: A suspension of 2-hydroxymethyl-6-chloroindole (1 mmol) with activated MnO2 (10 mmol) in DMF (30 mL) was stirred at room temperature for 12 hours. After completion of the reaction, the mixture was filtered through a diatomaceous earth pad. The filtrate was concentrated under vacuum and the residue was purified by column chromatography to afford 6-chloro-1H-indole-2-carbaldehyde using EtOAc-hexane mixed solvent as eluent.

References

[1] European Journal of Medicinal Chemistry, 2016, vol. 121, p. 561 - 577
[2] Patent: US2003/144282, 2003, A1
[3] Journal of Medicinal Chemistry, 2007, vol. 50, # 6, p. 1380 - 1400
[4] Patent: US2008/9485, 2008, A1. Location in patent: Page/Page column 31
[5] Journal of Medicinal Chemistry, 2014, vol. 57, # 2, p. 364 - 377

6-Chloro-1H-indole-2-carbaldehyde Preparation Products And Raw materials

Raw materials

Ethanol Manganese dioxide Diethyl oxalate Tetrahydrofuran Diethyl ether
Lithium Aluminum Hydride Hydrochloric acid Acetic acid Potassium 4-Chloro-2-nitrotoluene

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Preparation Products

6-Chloro-1H-indole-2-carbaldehyde Suppliers

Global Suppliers ( 42)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
ShangHai AmK Pharmaceutical Technology Co., Ltd. 微信 18019252918 18019252918 sale@amkchem.com China 14961 55
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
Shanghai Chenzhu Pharmaceutical Co., Ltd. 13162380607 1696175688@qq.com China 835 55
Shanghai YuanYe Biotechnology Co., Ltd. 18916372613 yanzihan@shyuanye.com China 87240 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Hangzhou Molcore Biopharmatech Co.,Ltd 400-711-5280 86-571-81025280 sales@molcore.com China 9957 58
Aikon International Limited 025-66113011 19370895928 qzhang@aikonchem.com China 15390 58
Suzhou Nuoouman Biological Technology Co., Ltd. 15026866316 180642609@qq.com China 4965 58
Shanghai SPAR pharmaceutical technology co., LTD 021-000000 admin@jingshipharmatech.com China 9942 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
ShangHai AmK Pharmaceutical Technology Co., Ltd. 55
Cool Pharm, Ltd 58
Shanghai Chenzhu Pharmaceutical Co., Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Amadis Chemical Company Limited 58
Hangzhou Molcore Biopharmatech Co.,Ltd 58
Aikon International Limited 58
Suzhou Nuoouman Biological Technology Co., Ltd. 58
Shanghai SPAR pharmaceutical technology co., LTD 58

6-Chloro-1H-indole-2-carbaldehyde Spectrum

6-CHLORO-1H-INDOLE-2-CARBALDEHYDE(53590-59-3)1HNMR6-CHLORO-1H-INDOLE-2-CARBALDEHYDE(53590-59-3)1HNMR

53590-59-3 (6-Chloro-1H-indole-2-carbaldehyde) Related Search:

4,6-Dichloro-1H-indole-2-carbonyl chloride 6-Chloroindole-2-carboxylic acid ethyl ester 6-Chloroindole-2-carboxylic acid 4,6-Dichloro-1H-indole-2-carboxylic acid Ethyl 4,6-dichloroindole-2-carboxylate
6-Chloro-1H-indole-2-carboxylic acid methyl ester alpha-Phenyl-1-(2-phenylethyl)-4-piperidinemethanol Ethyl 4,6-dichloro-3-formyl-1H-indole-2-carboxylate 6-Chloro-4-fluoro-1H-indole-2-carboxylic acid 6-Chloro-7-methyl-1H-indole-2-carboxylic acid
6,7-Dichloro-1H-indole-2-carboxylic acid ethyl ester (Z)-2-Carboxy-4,6-dichloroindole-3-(2'-phenyl-2'-carboxy)-ene 4,6-Dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propenyl]-1H-indole-2-carboxylic acid sodium salt Ethyl 3-(2-carboxy-vinyl)-4,6-dichloro-1H-indole-2-carboxylate 6,7-Dichloro-1H-indole-2-carboxylic acid
1H-Indole-2-carboxylic acid,6-chloro-4-fluoro-3-formyl-,ethyl ester 1-(beta-Dimethylaminoaethyl)-2-ethoxycarbonyl-3-ethoxy-6-chlor-indol-t oluol-4-sulfonat 4,6-Dichloro-3-hydroxymethyl-1H-indole-2-carboxylic acid ethyl ester

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1H-Indole-2-carboxaldehyde, 6-chloro- 6-Chloro-1H-indole-2-carbaldehyde 53590-59-3