Benzamidine hydrochloride hydrate
- CAS No.
- 206752-36-5
- Chemical Name:
- Benzamidine hydrochloride hydrate
- Synonyms
- BENZAMIDINE HCL HYDRATE;Imino(phenyl)methylamine;BENZAMIDINIUM CHLORIDE HYDRATE;BENZAMIDINE HYDROCHLORIDE HYDRATE;[amino(phenyl)methylidene]azanium;BENZAMIDINE HYDROCHLORIDE N-HYDRATE;AMIDINOBENZENE HYDROCHLORIDE HYDRATE;BENZAMIDINE HYDROCHLORIDE HYDRATE FO;BENZAMIDINE HYDROCHLORIDE MONOHYDRATE;Benzamidine hydrochloride hydrate,98%
- CBNumber:
- CB4694173
- Molecular Formula:
- C7H11ClN2O
- Molecular Weight:
- 174.63
- MDL Number:
- MFCD00066285
- MOL File:
- 206752-36-5.mol
- MSDS File:
- SDS
Melting point | 86-88 °C(lit.) |
---|---|
storage temp. | 2-8°C |
solubility | H2O: soluble50mg/mL, clear to slightly hazy, colorless to faintly yellow |
form | Powder |
color | White to off-white |
PH | 5 (50g/l, H2O, 20℃) |
Water Solubility | soluble |
Sensitive | Hygroscopic |
BRN | 3594959 |
CAS DataBase Reference | 206752-36-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36-37/39 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | CV6260000 | |||||||||
F | 3-21 | |||||||||
TSCA | Yes | |||||||||
HS Code | 2925 29 00 | |||||||||
NFPA 704 |
|
Benzamidine hydrochloride hydrate price More Price(39)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 8.20122 | Benzamidine hydrochloride hydrate for synthesis | 206752-36-5 | 2g | $41.8 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.20122 | Benzamidine hydrochloride hydrate for synthesis | 206752-36-5 | 25g | $125 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.20122 | Benzamidine hydrochloride hydrate for synthesis | 206752-36-5 | 1kg | $1250 | 2024-03-01 | Buy |
Alfa Aesar | A16002 | Benzamidine hydrochloride hydrate, 98%, water ca 10-14% | 206752-36-5 | 5g | $27.65 | 2024-03-01 | Buy |
Alfa Aesar | A16002 | Benzamidine hydrochloride hydrate, 98%, water ca 10-14% | 206752-36-5 | 25g | $78 | 2024-03-01 | Buy |
Benzamidine hydrochloride hydrate Chemical Properties,Uses,Production
Chemical Properties
white fine crystalline powder
Uses
Benzamidine hydrochloride hydrate has been used:
- in western blot analysis
- in immunoprecipitation
- in the purification of yeast dynein
- as a protease inhibitor in the preparation of brush-border membrane vesicles
- for the processing of human synovial fluid, blood and eye sleep
- to prevent non-specific degradation of cartilages
Uses
Benzamidine hydrochloride hydrate is a reversible inhibitor of trypsin, trypsin-like enzymes, and serine proteases. It is a proteolytic inhibitor and apoptosis reagent.
Application
Benzamidine hydrochloride hydrate has been used:
in western blot analysis
in immunoprecipitation
in the purification of yeast dynein
as a protease inhibitor in the preparation of brush-border membrane vesicles
for the processing of human synovial fluid, blood and eye sleep
to prevent non-specific degradation of cartilages
Biological Activity
Peptidase inhibitor.
Benzamidine HCl is a reversible inhibitor of trypsin, trypsin-like enzymes, and serine proteases.A concentration of approximately 1 mM is used for general protease inhibition. To inhibit proteases from yeast, a range of 0.5 to 4.0 mM is used and it is for the most part interchangeable with pepstatin A.
In addition to being a strong competitive inhibitor of trypsin, benzamidine HCl has been also shown to be a strong competitive inhibitor of thrombin and plasmin. It was also found to be as effective as aprotinin in the prevention of glucagon degradation in human plasma.
Biochem/physiol Actions
Peptidase inhibitor.
Purification Methods
Recrystallise it from dilute HCl (crystals contain xH2O) or EtOH/few drops HCl; dry it in a vacuum. It is a proteolytic inhibitor [Jeffcoate & White J Clin Endocrinol Metab 38 155 1974, Beilstein 9 IV 898.]
Preparation and handling
Benzamidine HCl is soluble in water and alcohol. Solubility testing in water at a concentration of 50 mg/ml yields a clear solution with heating. Benzamidine HCl is sensitive to oxidation. It is recommended to prepare solutions fresh each time in degassed water prior to use. However, frozen aliquots stored under inert gas, to exclude air, may be stable for a short time. Insufficient information is available to assess the shelf-life of a frozen solution.
Precautions
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents. It is hygroscopic in nature.
Benzamidine hydrochloride hydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21686 | 55 |
career henan chemical co | +86-0371-86658258 15093356674; | sales@coreychem.com | China | 29914 | 58 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5909 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
View Lastest Price from Benzamidine hydrochloride hydrate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2021-10-29 | Benzamidine hydrochloride hydrate
206752-36-5
|
US $0.00 / KG | 1KG | 98% | 5000kgs/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2021-07-02 | Benzamidine hydrochloride hydrate
206752-36-5
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | ||
2019-07-06 | Benzamidine hydrochloride hydrate
206752-36-5
|
US $1.00 / kg | 1g | 99% | 100KG | Career Henan Chemical Co |
- Benzamidine hydrochloride hydrate
206752-36-5
- US $0.00 / KG
- 98%
- WUHAN FORTUNA CHEMICAL CO., LTD
- Benzamidine hydrochloride hydrate
206752-36-5
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
- Benzamidine hydrochloride hydrate
206752-36-5
- US $1.00 / kg
- 99%
- Career Henan Chemical Co