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Propionaldehyde structure
Chemical Name:
Propin;C2H5CHO;PROPANAL;Propional;FEMA 2923;n-Propylal;NCI-C61029;Propionald;N-PROPANAL;1-PROPANAL
Molecular Formula:
Formula Weight:
MOL File:

Propionaldehyde Properties

Melting point:
-81 °C
Boiling point:
48 °C
0.805 g/mL at 25 °C(lit.)
vapor density 
2 (vs air)
vapor pressure 
18.77 psi ( 55 °C)
refractive index 
n20/D 1.362(lit.)
Flash point:
−16 °F
storage temp. 
organic solvents: soluble
Specific Gravity
0.815 (20/4℃)
explosive limit
Water Solubility 
540 g/L (20 ºC)
Air Sensitive
JECFA Number
Stable. Highly flammable. Incompatible with oxidizing agents, strong acids, strong bases.
CAS DataBase Reference
123-38-6(CAS DataBase Reference)
NIST Chemistry Reference
EPA Substance Registry System
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
  • NFPA
Hazard Codes  F,Xi,Xn
Risk Statements  11-36/37/38-R36/37/38-R11-41-37/38-20/22
Safety Statements  9-16-29-S9-S29-S16
RIDADR  UN 1275 3/PG 2
WGK Germany  1
RTECS  UE0350000
Autoignition Temperature 404 °F
HazardClass  3
PackingGroup  II
HS Code  29121900
Hazardous Substances Data 123-38-6(Hazardous Substances Data)
Toxicity LD50 orally in rats: 1.4 g/kg; LC for rats in air: 8000 ppm (Smyth)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P403 Store in a well-ventilated place.
P403+P235 Store in a well-ventilated place. Keep cool.

NFPA 704

Diamond Hazard Value Description
2 2
Health   2 Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine)
Flammability   3 Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone)
Instability   2 Undergoes violent chemical change at elevated temperatures and pressures, reacts violently with water, or may form explosive mixtures with water (e.g. white phosphorus, potassium, sodium)

(NFPA, 2010)

Propionaldehyde price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 538124 Propionaldehyde reagent grade, 97% 123-38-6 1l $158 2018-11-13 Buy
Sigma-Aldrich 538124 Propionaldehyde reagent grade, 97% 123-38-6 250ml $77.9 2018-11-13 Buy
TCI Chemical P0498 Propionaldehyde >98.0%(GC) 123-38-6 25mL $14 2018-11-22 Buy
TCI Chemical P0498 Propionaldehyde >98.0%(GC) 123-38-6 500mL $20 2018-11-22 Buy
Alfa Aesar A16146 Propionaldehyde, 97% 123-38-6 500ml $24.8 2018-11-13 Buy

Propionaldehyde Chemical Properties,Uses,Production

Chemical Properties

colourless liquid

Chemical Properties

Propionaldehyde is a colorless liquid. Very strong, intensive fruit odor


Propionaldehyde is produced by the oxo reaction of ethylene with carbon monoxide and hydrogen. n-Propyl alcohol is produced by hydrogenation of propionaldehyde, and propionic acid is made by oxidation of propionaldehyde.
n-Propyl alcohol is used as solvent in printing inks and as an intermediate in the preparation of agricultural chemicals. Propionic acid is used as a grain preservative as, for example, in preventing spoilage of wet corn used as animal feed. The use of propionic acid as a grain preservative is an alterna tive to drying by heating, which consumes fuel, and is considered mostly when fuel is expensive.


Propionaldehyde is used in the productionof propionic acid, propionic anhydride, andmany other compounds. It is formed in theoxidative deterioration of corn products, suchas corn chips. It occurs in automobile exhaustgases.


Manufacture of propionic acid, polyvinyl, and other plastics; synthesis of rubber chemicals; disin- fectant; preservative.


ChEBI: An aldehyde that consists of ethane bearing a formyl substituent. The parent of the class of propanals.

General Description

A clear colorless liquid with an overpowering fruity-like odor. Less dense than water. Flash point 15°F. Vapors are heavier than air.

Air & Water Reactions

Highly flammable. Soluble in water.

Reactivity Profile

Propionaldehyde may form explosive peroxides. Reacts vigorously with oxidizing agents. Explosive in the form of vapor when exposed to heat or flame [Lewis]. Incompatible with strong bases and strong reducing agents. Vigorous polymerization reaction with methyl methacrylate. Polymerization may also occur in the presence of acids or caustics .


Flammable, dangerous fire risk, explosive limits in air 3.0–16%. Upper respiratory tract irri- tant.

Health Hazard

Vapors will irritate nose and throat, and may cause nausea and vomiting. Liquid causes eye irritation.

Health Hazard

Propionaldehyde is a mild irritant to humanskin and eyes. The irritation effect from40 mg was severe in rabbits’ eyes. The toxicityof this compound observed in test animalswas low. Subcutaneous administration in ratsexhibited the symptoms of general anestheticeffect, convulsion, and seizure. Inhalationtoxicity was determined to be low. A concentrationof 8000 ppm (19,000 mg/m3) inair was lethal to rats.
LD50 value, oral (rats): 1400 mg/kg
LD50 subcutaneous (rats): 820 mg/kg.

Fire Hazard

Behavior in Fire: Vapor is heavier than air and may travel considerable distance to a source of ignition and flash back.

Safety Profile

Moderately toxic by skin contact, ingestion, and subcutaneous routes. Mddly toxic by inhalation. A skin and severe eye irritant. Flammable liquid. Dangerous fire hazard when exposed to heat or flame; reacts vigorously with oxidizers. Explosive in the form of vapor when exposed to heat or flame. Vigorous polymerization reaction with methyl methacrylate. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes. See also ALDEHYDES.

Potential Exposure

Used as a synthetic flavoring; as a disinfectant and preservative; to make propionic acid; in plastic and rubber manufacturing; to make alkyl resins and plasticizers.

First aid

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek med- ical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin res- cue breathing (using universal precautions, including resusci- tation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. Medical observation is recommended for 24?48 hours after breathing overexposure, as pulmonary edema may be delayed. As first aid for pulmo- nary edema, a doctor or authorized paramedic may consider administering a drug or other inhalation therapy.


UN1275 Propionaldehyde, Hazard Class: 3; Labels: 3-Flammable liquid.

Purification Methods

the aldehyde with CaSO4 or CaCl2, and fractionally distil it under nitrogen or in the presence of a trace of hydroquinone (to retard oxidation). Blacet and Pitts [J Am Chem Soc 74 3382 1952] repeatedly distilled the middle fraction in a vacuum until it no longer gave a solid polymer when cooled to -80o. It is stored with CaSO4. [Beilstein 1 IV 3165.]


Incompatible with strong acids; amines. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoa- cids, epoxides. Strong caustics; reducing agents can cause explosive polymerization. Can self-ignite if finely dispersed on porous or combustible material, such as fabric. Heat or UV light can cause decomposition. Aldehydes are fre- quently involved in self-condensation or polymerization reactions. These reactions are exothermic; they are often catalyzed by acid. Aldehydes are readily oxidized to give carboxylic acids. Flammable and/or toxic gases are gener- ated by the combination of aldehydes with azo, diazo com- pounds, dithiocarbamates, nitrides, and strong reducing agents. Aldehydes can react with air to give first peroxo acids, and ultimately carboxylic acids. These autoxidation reactions are activated by light, catalyzed by salts of transition metals, and are autocatalytic (catalyzed by the products of the reaction). The addition of stabilizers (anti- oxidants) to shipments of aldehydes retards autoxidation

Waste Disposal

Propionaldehyde is destroyed by burning in achemical incinerator equipped with an afterburnerand scrubber. Permanganate oxidationis a suitable laboratory method of destruction.

Propionaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

Propionaldehyde Suppliers

Global( 223)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 21967 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32457 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114 CHINA 6374 58
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 24001 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254 CHINA 20095 58
(323) 306-3136
(626) 453-0409 United States 8409 58
career henan chemical co
+86-371-86658258 CHINA 20104 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 021-20337333/400-620-6333
021-50323701 China 24991 65

View Lastest Price from Propionaldehyde manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-20 Propionaldehyde
US $1.00 / kg 1kg 99% 1000kg career henan chemical co

Propionaldehyde Spectrum

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