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PARAFFIN

PARAFFIN
PARAFFIN structure
CAS No.
8012-95-1
Chemical Name:
PARAFFIN
Synonyms
OIL;molol;saxol;NUJOL;glymol;kaydol;balneol;bayol55;drakeol;penreco
CBNumber:
CB5266104
Molecular Formula:
unspecified
Formula Weight:
0
MOL File:
Mol file

PARAFFIN Properties

Melting point:
-24 °C (lit.)
Boiling point:
300 °C (lit.)
Density 
0.827-0.890 g/mL at 20 °C
refractive index 
n20/D 1.467(lit.)
Flash point:
>300°C
storage temp. 
Store at room temperature.
solubility 
Practically insoluble in ethanol (95%), glycerin, and water; soluble in acetone, benzene, chloroform, carbon disulfide, ether, and petroleum ether. Miscible with volatile oils and fixed oils, with the exception of castor oil.
form 
light oil
Specific Gravity
0.870 (20/4℃)
color 
white
Odor
Odorless
Water Solubility 
Soluble in ether. Sparingly soluble in ethanol. Not miscible or difficult to mix in water.
Merck 
14,7023
Substances Added to Food (formerly EAFUS)
MINERAL OIL, WHITE
EPA Substance Registry System
Paraffin oils (8012-95-1)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07,GHS08
Signal word  Danger
Hazard statements  H304-H319
Precautionary statements  P264-P280i-P305+P351+P338-P337+P313-P301+P310-P331
Hazard Codes  Xi,N
Risk Statements  36-51/53
Safety Statements  26-61
WGK Germany  1
RTECS  PY8030000
Autoignition Temperature 245°C
TSCA  Yes
HS Code  27122090
Toxicity LD50 oral in rat: > 24gm/kg
NFPA 704
1
0 0

PARAFFIN price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 18512 Paraffin oil puriss., meets analytical specification of Ph. Eur., BP, viscous liquid 8012-95-1 1l $67.9 2021-12-16 Buy
Sigma-Aldrich 1443952 Mineral oil United States Pharmacopeia (USP) Reference Standard 8012-95-1 1.5ml $399 2021-12-16 Buy
Alfa Aesar L14480 Nujol, for IR spectroscopy 8012-95-1 50ml $23.1 2021-12-16 Buy
Alfa Aesar L14480 Nujol, for IR spectroscopy 8012-95-1 500ml $29.7 2021-12-16 Buy
TRC P193283 ParaffinOils 8012-95-1 250ml $65 2021-12-16 Buy

PARAFFIN Chemical Properties,Uses,Production

Chemical Properties

Clear colorless oil

Chemical Properties

Mineral oil is a transparent, colorless, viscous oily liquid, without fluorescence in daylight. It is practically tasteless and odorless when cold, and has a faint odor of petroleum when heated.

Uses

Mineral oil is a lubricant and is used as a solvent for inks in the printing industry.

Uses

Paraffin Oils is a useful organic solvent for isolating the nucleus of the gian amphibian oocyte.

Uses

Laxative; pharmaceutic aid (solvent).

Production Methods

Mineral oil is obtained by distillation of petroleum. The lighter hydrocarbons are first removed by distillation and the residue is then redistilled between 330–390°C. The distillate is chilled and the solid fractions are removed by filtration. The filtrate is then further purified and decolorized by high-pressure hydrogenation or sulfuric acid treatment; the purified filtrate is then filtered through adsorbents. The liquid portion obtained is distilled and the portion boiling below 360°C is discarded. A suitable stabilizer may be added to the mineral oil;

brand name

Balneol (Solvay Pharmaceuticals); Neo-Cultol (Fisons); Nujol (Schering-Plough HealthCare).

General Description

Transparent colorless oily liquid. Practically tasteless and odorless, even when warmed.

Air & Water Reactions

Flammable. Insoluble in water.

Reactivity Profile

OIL. [MINERAL] may be incompatible with strong oxidizing agents like nitric acid. Charring may occur followed by ignition of unreacted oil and other nearby combustibles. In other settings, mostly unreactive. Not affected by aqueous solutions of acids, alkalis, most oxidizing agents, and most reducing agents. Burns exothermically when heated sufficiently or when ignited in the presence of air, oxygen or strong oxidizing agents.

Hazard

Inhalation of vapor or particulates can causeaspiration pneumonia. Combustible liquid. Upperrespiratory tract irritant. Questionable carcinogen.

Health Hazard

Highly refined mineral oil mist is of low toxicity.

Fire Hazard

PARAFFIN is combustible.

Pharmaceutical Applications

Mineral oil is used primarily as an excipient in topical pharmaceutical formulations, where its emollient properties are exploited as an ingredient in ointment bases. It is additionally used in oil-in-water emulsions,as a solvent, and as a lubricant in capsule and tablet formulations, and to a limited extent as a mold-release agent for cocoa butter suppositories. It has also been used in the preparation of microspheres and as a vaccine adjunct.
Therapeutically, mineral oil has been used as a laxative.It is indigestible and thus has limited absorption. Mineral oil is used in ophthalmic formulations for its lubricant properties. It is also used in cosmetics and some food products.

Safety Profile

A human teratogen by inhalation that causes testicular tumors in the fetus. Inhalation of vapor or particulates can cause aspiration pneumonia. A skin and eye irritant. Highly purified food grades are of low toxicity. Questionable human carcinogen producing gastrointestinal tumors. Slightly combustible liquid when exposed to heat or flame. To fight fire, use dry chemical, CO2, foam. When heated to decomposition it emits acrid smoke and fumes.

Safety

Mineral oil is used as an excipient in a wide variety of pharmaceutical formulations. It is also used in cosmetics and in some food products.
Therapeutically, mineral oil has been used in the treatment of constipation, as it acts as a lubricant and stool softener when taken orally. Daily doses of up to 45mL have been administered orally, while doses of up to 120mL have been used as an enema. However, excessive dosage of mineral oil, either orally or rectally, can result in anal seepage and irritation, and its oral use as a laxative is not considered desirable.
Chronic oral consumption of mineral oil may impair the appetite and interfere with the absorption of fat-soluble vitamins. Prolonged use should be avoided. Mineral oil is absorbed to some extent when emulsified and can lead to granulomatous reactions. Similar reactions also occur upon injection of the oil;injection may also cause vasospasm.
The most serious adverse reaction to mineral oil is lipoid pneumonia caused by aspiration of the oil.Mineral oil can enter the bronchial tree without eliciting the cough reflex.With the reduction in the use of mineral oil in nasal formulations, the incidence of lipoid pneumonia has been greatly reduced. However, lipoid pneumonia has also been associated with the use of mineral oil-containing cosmetics and ophthalmic preparations.It is recommended that products containing mineral oil not be used in very young children, the elderly, or persons with debilitating illnesses.
Given its widespread use in many topical products, mineral oil has been associated with few instances of allergic reactions. The WHO has not specified an acceptable daily intake of mineral oil given the low concentration consumed in foods.
LD50 (mouse, oral): 22 g/kg

storage

Mineral oil undergoes oxidation when exposed to heat and light. Oxidation begins with the formation of peroxides, exhibiting an ‘induction period’. Under ordinary conditions, the induction period may take months or years. However, once a trace of peroxide is formed, further oxidation is autocatalytic and proceeds very rapidly. Oxidation results in the formation of aldehydes and organic acids, which impart taste and odor. Stabilizers may be added to retard oxidation; butylated hydroxyanisole, butylated hydroxytoluene, and alpha tocopherol are the most commonly used antioxidants.
Mineral oil may be sterilized by dry heat.
Mineral oil should be stored in an airtight container, protected from light, in a cool, dry place.

Purification Methods

Treat the oil with fuming H2SO4 (care), then wash it with water and dilute aqueous NaOH, then percolate it through activated silica gel. Paraffin Wax. Melt the wax in the presence of NaOH, wash it with water until all of the base had been removed. The paraffin is allowed to solidify after each wash. Finally, 5g of paraffin is melted by heating it on a water-bath, then shaken for 20-30minutes with 100mL of boiling water and and dry the melt under vacuum.

Incompatibilities

Incompatible with strong oxidizing agents.

Regulatory Status

GRAS listed. Accepted in the UK for use in certain food applications. Included in the FDA Inactive Ingredients Database (dental preparations; IV injections; ophthalmic preparations; oral capsules and tablets; otic, topical, transdermal, and vaginal preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

PARAFFIN Preparation Products And Raw materials

Raw materials

Preparation Products


PARAFFIN Suppliers

Global( 132)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 linda@hubeijusheng.com CHINA 23035 58
Shandong chuangyingchemical Co., Ltd.
18853181302
sale@chuangyingchem.com CHINA 5917 58
Shanghai Longyu Biotechnology Co., Ltd.
+8615821988213
+86 15821988213 info@longyupharma.com China 2500 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
HENAN BON INDUSTRIAL CO.,LTD
0371-55170695
info@hnbon.com CHINA 26742 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com China 47498 58
Shaanxi Dideu Medichem Co. Ltd
13772537765
029-88380327 1010@dideu.com CHINA 3993 58
Zhuozhou Wenxi import and Export Co., Ltd
+8613111626072 (WhatsApp)
Wechat: +8613111626072 Wickr me: waynehu zzwenxi@126.com CHINA 13187 58
Hebei Runbin Biotechnology Co. LTD
13180553332 13180553332
2179877681@qq.com CHINA 1000 58

View Lastest Price from PARAFFIN manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2022-01-17 Paraffins
8012-95-1
US $7.00 / KG 100KG 99% 1000kg Hebei Yime New Material Technology Co., Ltd.
2022-01-07 PARAFFIN
8012-95-1
US $1.00 / g 1g 99 20tons Shanghai Longyu Biotechnology Co., Ltd.
2021-12-01 PARAFFIN
8012-95-1
US $1.70 / KG/CTN 10g 99% 10000kg Hebei Crovell Biotech Co Ltd

PARAFFIN Spectrum


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