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Weight loss drugs Drug Interactions safety Uses
LORCASERIN structure
Chemical Name:
Apd356;Ar-10a;Apd-356;Apd 356;LORCASERIN;Unii-637E494o0z;Lotcaserin Freebase;(R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine;(1R)-8-Chloro-2,3,4,5-tetrahydro-1-Methyl-1H-3-benzazepine
Molecular Formula:
Formula Weight:
MOL File:


Boiling point:
288 ºC
Flash point:
128 ºC
storage temp. 
-20?C Freezer



Manufacturer Product number Product description CAS number Packaging Price Updated Buy

LORCASERIN Chemical Properties,Uses,Production

Weight loss drugs

Lorcaserin is a new drug for the treatment of obesity , belonging to oral potent selective serotonin 2C receptor agonists, lorcaserin hydrochloride is successfully developed by the US company Arena, on June 27, 2012 by the US FDA it is approved for marketing, as adjuvant therapy for obesity or merge with at least one weight-related complications in overweight adults in low-calorie diet and exercise basis . Clinical studies show that the drug can reduce weight of obesity and overweight patients ,it can improve obesity-related metabolic parameters, and it is well tolerated. Lorcaserin affinity for the 5-HT2c 100 times higher than the 5-HT2B (valvular heart disease risk) ,it has good safety,it is the first FDA-approved weight-loss drug after 1999 . In a year of Lorcaserin treatment, the average weight loss ranges from 3 to 3.7 percent.

Drug Interactions

Due to the theoretical possibility of the mechanism of lorcaserin and serotonin syndrome, when lorcaserin is used in combination with the serotonergic neurotransmitter system drugs, extreme caution should be paid, including triptans monoamine oxidase inhibitor agent selective serotonin reuptake inhibitor selective serotonin and norepinephrine reuptake inhibitors, tricyclic antidepressants bupropion dextromethorphan, lithium tramadol and St. John's wort , etc. In addition, when the present product with CYP2D6 substrates when combined with the need to be cautious, because the product can increase the exposure of these drugs.
The above information is edited by the Chemicalbook of Tian Ye.


Lorcaserin has good tolerability and safety, lorcaserin is used in non-diabetic patients, the most common adverse reactions are headache, dizziness, fatigue, nausea, dry mouth and constipation. This product is used in patients with diabetes, common adverse reactions are headache, back pain, cough, low blood sugar and fatigue.studies have found that lorcaserin and placebo are Similar in the proportion of serious adverse reactions, lorcaserin does not increase the incidence of valvular heart disease. After lorcaserin treatment , the incidence of depression is lower , the research shows that the proportion of depression led by lorcaserin 10mgbid, 10mgqd and placebo are 1.9%, 1.1% and 1.8%, emotional low incidence rates are 0.6%, 0.9% and 0.9%, the proportion of suicidal thoughts are 0.9%, 0.6% and 0.7% .the product is pregnancy X-class , pregnant women are disabled; whether this product is secreted by milk is unknown, breast-feeding women need to weigh on the use of the drug; this product is not recommended for children.


diet pills

Chemical Properties

Yellow Oil


A novel selective 5-HT2C-receptor agonist for the treatment of obesity.


ChEBI: A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine substituted at position 1 by a methyl group and a t position 6 by a chloro group.

LORCASERIN Preparation Products And Raw materials

Raw materials

Preparation Products


Global( 124)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 22043 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20786 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825 CHINA 2461 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 CHINA 552 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 CHINA 894 55
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 24118 58
HaBo Hong Kong Co., Limited.
+86-25-18512596065 CHINA 681 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254 CHINA 20229 58
Haihang Industry Co.,Ltd
+86 531 8582 1093 CHINA 4558 58
Cangzhou Wanyou New Material Technology Co.,Ltd
18631714998 CHINA 241 58

View Lastest Price from LORCASERIN manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-04-12 LORCASERIN
US $1.00 / g 10g 99% 10000000 Kilogram/Kilograms per Day Cangzhou Wanyou New Material Technology Co.,Ltd
2018-08-08 LORCASERIN
US $1.00 / KG 1KG 99% 100kg career henan chemical co
2018-03-08 Lorcaserin
US $1000.00 / KG 10G 99.5% 10kg Hubei XinRunde Chemical Co., Ltd.

616202-92-7(LORCASERIN)Related Search:

  • (R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
  • Apd 356
  • Apd356
  • Apd-356
  • Ar-10a
  • Unii-637E494o0z
  • 616202-92-7
  • Amines
  • Aromatics
  • (1R)-8-Chloro-2,3,4,5-tetrahydro-1-Methyl-1H-3-benzazepine
  • Lotcaserin Freebase
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
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