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CHLORCYCLIZINE

CHLORCYCLIZINE
CHLORCYCLIZINE structure
CAS No.
82-93-9
Chemical Name:
CHLORCYCLIZINE
Synonyms
Perazyl;Histantin;Trihistan;Alergicide;Di-paralen;Histantine;piparalene;Chlorcycline;Chlorocycline;CHLORCYCLIZINE
CBNumber:
CB6347282
Molecular Formula:
C18H21ClN2
Formula Weight:
300.83
MOL File:
82-93-9.mol

CHLORCYCLIZINE Properties

Melting point:
25°C
Boiling point:
bp0.1-0.15 137-145°
Density 
1.0732 (rough estimate)
refractive index 
1.5749 (estimate)
pka
pKa 2.43(H2O t = 25 c = 0.002 to 0.01)(Approximate);7.81(H2O t = 25 c = 0.002 to 0.01) (Uncertain)
Water Solubility 
300.8mg/L(37.5 ºC)
EWG's Food Scores
1
FDA UNII
M26C4IP44P
ATC code
R06AE04

CHLORCYCLIZINE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0008666 CHLORCYCLIZINE 95.00% 82-93-9 1G $1358.28 2021-12-16 Buy

CHLORCYCLIZINE Chemical Properties,Uses,Production

Originator

Perazil,Burroughs-Wellcome,US,1949

Manufacturing Process

0.08 mol (19 9) of 4-chlorobenzhydryl chloride and 0.16 mol (16 g) of methylpiperazine were mixed in about 20 cc of dry benzene. The flask containing the reaction mixture was covered by a watch glass and set in a steam bath, and heating was continued for 6 hours. The contents of the flask were partitioned between ether and water and the ethereal layer was washed with water until the washings were neutral. The ethereal layer was extracted successively with 30 and 10 cc portions of 3 N hydrochloric acid. On evaporation of the ether layer there remained a residue of 2.5 9. The aqueous extracts were united and basified with concentrated alkali. The oily base was taken into ether and dried over potassium carbonate. On evaporation of the ether, N-methyl-N'-(4-chlorobenzhydryl) piperazine was recovered in the form of a viscous oil in 75% yield. The N-methyl-N'-(4-chlorobenzhydryl) piperazine was dissolved in absolute alcohol and ethanolic hydrogen chloride added in excess. The dihydrochloride crystallized on addition of absolute ether and was recrystallized from the same solvent mixture in the form of longish prisms melting at about 216°C.

brand name

Di-Paralene (Abbott).

Therapeutic Function

Antihistaminic

CHLORCYCLIZINE Preparation Products And Raw materials

Raw materials

Preparation Products


CHLORCYCLIZINE Suppliers

Global( 19)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
Dayang Chem (Hangzhou) Co.,Ltd.
17705817739 +86-571-88938639
+86-571-88938652,+86-571- 88492614 info@dycnchem.com CHINA 52932 58
Syntechem Co.,Ltd Please Email
E-Mail Inquiry info@syntechem.com China 13009 57
BOC Sciences 16314854226
info@bocsci.com United States 21113 65
Chongqing Chemieliva Pharmaceutical Co., Ltd. 023-67770219
+86 (23) 6777-0220 jessica.hu@chemieliva.com China 1228 60
Chengdu Saint - Kay Biotechnology Co., Ltd. 15882256948
676046971@qq.com China 4510 58
Energy Chemical 400-005-6266 021-58432009
021-58436166 marketing@energy-chemical.com China 44948 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369
3477467573@qq.com China 8623 58
Hubei xingongli Chemical Co., Ltd 15172325309 027-59503710-
027-59503710 1018282255@qq.com;1018285511@qq.com China 9296 58

82-93-9(CHLORCYCLIZINE)Related Search:


  • 1-((4-chlorophenyl)phenylmethyl)-4-methylpiperazine
  • 1-(4-Chlorobenzhydryl)-4-methylpiperazine
  • 1-(p-chloro-alpha-phenylbenzyl)-4-methyl-piperazin
  • 1-(p-Chloro-alpha-phenylbenzyl)-4-methylpiperazine
  • 1-(PARA-CHLORO-ALPHA-PHENYLBENZYL)-4-METHYLPIPERAZINE
  • CHLORCYCLIZINE
  • 1-[(4-Chlorophenyl)phenylmethyl]-4-methylpiperazine
  • Alergicide
  • Chlorcycline
  • Chlorocycline
  • Chlorocyclizine
  • Compound 47-282
  • compound47-282
  • Di-paralen
  • histachlorazene
  • Histantin
  • Histantine
  • N-Methyl-N'-(4-chlorobenzhydryl)piperazine
  • n-methyl-n’-(4-chlorobenzhydryl)piperazine
  • Perazyl
  • piparalene
  • Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-4-methyl-
  • Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-methyl-
  • Trihistan
  • 1-[α-(p-Chlorophenyl)benzyl]-4-methylpiperazine
  • Chlorcyclizine >=98% (HPLC)
  • Chlorcyclizine free base
  • 82-93-9
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