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4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene

4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene structure

CAS No.: 461432-23-5

Chemical Name:: 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene

Synonyms: 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene;Dapagliflozin Bromo impurity;Benzene, 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]-;Dapagliflozin-13;Dapaglifozin DAP Bromo;5-broMo-2-chloro-4’Dapagliflozin Impurity 15;4-(Dibenzofuranyl)boronic;Dapagliflozin Impurity 82;Dapagliflozin Intermediate 1

CBNumber:: CB71456759

Molecular Formula:: C15H14BrClO

Molecular Weight:: 325.63

MDL Number:: MFCD11042292

MOL File:: 461432-23-5.mol

Last updated:2024-08-21 22:41:43

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4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Properties

Boiling point	393.0±32.0 °C(Predicted)
Density	1.371±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
form	Low-Melting Solid
color	White to Off-White
Stability	Stable under recommended storage conditions., Stable Under Recommended Storage C
InChI	InChI=1S/C15H14BrClO/c1-2-18-14-6-3-11(4-7-14)9-12-10-13(16)5-8-15(12)17/h3-8,10H,2,9H2,1H3
InChIKey	ZUNCHZBITMUSRD-UHFFFAOYSA-N
SMILES	C1(Cl)=CC=C(Br)C=C1CC1=CC=C(OCC)C=C1

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P280-P305+P351+P338
HS Code	2909309090

4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene price More Price(25)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	B682175	4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene	461432-23-5	1g	$460	2021-12-16	Buy
Biosynth Carbosynth	FB76075	4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene	461432-23-5	50g	$500	2021-12-16	Buy
ChemScene	CS-B0023	4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene 98.57%	461432-23-5	100g	$158	2021-12-16	Buy
Biosynth Carbosynth	FB76075	4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene	461432-23-5	10g	$180	2021-12-16	Buy
Matrix Scientific	083813	4-(5-Bromo-2-chlorobenzyl)phenyl ethyl ether 97%	461432-23-5	5g	$242	2021-12-16	Buy

Product number	Packaging	Price	Buy
B682175	1g	$460	Buy
FB76075	50g	$500	Buy
CS-B0023	100g	$158	Buy
FB76075	10g	$180	Buy
083813	5g	$242	Buy

4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Chemical Properties,Uses,Production

Uses

5-Bromo-2-chloro-4'-ethoxydiphenylmethane is a hydrocarbon derivative and can be used as an intermediate for dapagliflozin.

Synthesis

Oxalyl chloride (0.8 mL) was added to a solution of 5-bromo-2-chlorobenzoic acid (2 g) in dichloromethane (20 mL) and dimethylformamide (0.2 mL) under a nitrogen atmosphere. The reaction mixture was stirred for one hour at 25° C to 30° C. After completion of the reaction, the reaction mixture was concentrated under a vacuum at 40° C to 45° C. to obtain an oily residue. The oily residue was dissolved in dichloromethane (20 mL) and cooled to 0° C. To this solution, phenol (1.1 mL) and aluminium chloride (2.3 g) were added at 0° C. to 5° C. The reaction mixture was stirred at 0° C to 5° C for 2 hours. The reaction mixture was allowed to warm to about 20° C, and triethylsilane (3.4 mL) was slowly added to it at the same temperature. The reaction mixture was stirred for about 36 hours from 20° C to 25° C. After completion of the reaction, 4-bromo-1-chloro-2-(4-ethoxybenzyl)benzene was obtained by further purification.

4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene synthesis

Synthesis of 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene from (5-bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone

4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Preparation Products And Raw materials

Raw materials

Preparation Products

(2S,3R,4S,5S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6,6-bis(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol Bexagliflozin 4-(5-broMo-2-chlorobenzyl)phenol

4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene Suppliers

Global( 545)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Rochi Pharmaceutical Co.,Ltd.	21-38751876 +8615000076078	info@rochipharma.com	China	431	58
Suzhou Nordica Biopharma CO.,LTD	+8618136148818	anna.ran@nordicabio.com	China	298	58
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12446	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5866	58
Shanghai Joiny Pharmaceutical Co.,LTD	+8613681955282	gyd@joiny-pharma.com	China	250	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
Hangzhou ICH Biofarm Co., Ltd	+86-0571-28186870; +undefined8613073685410	sales@ichemie.com	China	990	58
Anhui Lianchuang Biological Medicine Co.,Ltd	+8613706129682	tiffany@langyupharm.com	China	86	58
Hebei Xinsheng New Material Technology Co., LTD.	+86-16632316109	xinshengkeji@xsmaterial.com	China	1090	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	994	58

Supplier	Advantage
Shanghai Rochi Pharmaceutical Co.,Ltd.	58
Suzhou Nordica Biopharma CO.,LTD	58
Hebei Mojin Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Shanghai Joiny Pharmaceutical Co.,LTD	58
Henan Bao Enluo International TradeCo.，LTD	58
Hangzhou ICH Biofarm Co., Ltd	58
Anhui Lianchuang Biological Medicine Co.,Ltd	58
Hebei Xinsheng New Material Technology Co., LTD.	58
Anhui Ruihan Technology Co., Ltd	58

View Lastest Price from 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-09-19	5-bromo-2-chloro-4’-ethoxydiphenylmethane 461432-23-5	US $999.00-666.00 / kg	1kg	99%	5000	HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
2024-09-19	5-bromo-2-chloro-4’-ethoxydiphenylmethane 461432-23-5	US $5.00-2.00 / KG	1KG	99%	10000kg	Hebei Chuanghai Biotechnology Co,.LTD
2024-09-19	5-bromo-2-chloro-4’-ethoxydiphenylmethane 461432-23-5	US $80.00 / kg	1kg	99.9%	500	hebei hongtan Biotechnology Co., Ltd

5-bromo-2-chloro-4’-ethoxydiphenylmethane
461432-23-5
US $999.00-666.00 / kg
99%
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

5-bromo-2-chloro-4’-ethoxydiphenylmethane
461432-23-5
US $5.00-2.00 / KG
99%
Hebei Chuanghai Biotechnology Co,.LTD

5-bromo-2-chloro-4’-ethoxydiphenylmethane
461432-23-5
US $80.00 / kg
99.9%
hebei hongtan Biotechnology Co., Ltd

461432-23-5(4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene)Related Search:

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(5-bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone 4-BROMO-1-CHLORO-2-ETHYLBENZENE 5-bromo-2-chloro-4’-ethoxydiphenylmethane

1of4

5-bromo-2-chloro-4’-ethoxydiphenylmethane 4-(5-Bromo-2-chlorobenzyl)phenyl ethyl ether Dapagliflozin Intermediate 1 4-broMo-1-chloro-2-[(4-ethoxyphenyl)Methyl]- 2-(4-Methoxybenzyl)-4-broMo-1-chlorobenzene 1-(5-broMo-2-chlorobenzyl)-4-ethoxybenzene 5-broMo-2-chloro-4&rsquo Dapagliflozin Intermediate II Dapagliflozin Intermediate 2 5-bromo-2-chloro-4'-ethoxydiphenylmethane###461432-23-5 (5-bromo-2-chlorobenzyl)-4-ethoxybenzene 4-(5-Brom-2-chlorbenzyl)phenyl-ethylether Dapagliflozin Impurity 15 Dapagliflozin-13 4-(Dibenzofuranyl)boronic 4-(5-Bromo-2-chlorobenzy)phenylethyl ester Dapagliflozin Impurity 82 4-Bromo-1-chloro-2-(4-ethoxybenzyl) Dapagliflozin Despyranose Bromo Impurity 4-Brom-1-chlor-2-(4-ethoxybenzyl)benzol 5-bromo-2-chloro-4’-ethoxydiphenylmethane ISO 9001：2015 REACH 4-(3-((1-ethoxyethoxy)methyl)-4-bromophenoxy)benzonitrile Supply 5-bromo-2-chloro-4'-ethoxydiphenylmethane Dapaglifozin DAP Bromo 5-bromo-2-chloro-4-ethoxydiphenylmethaneQ: What is 5-bromo-2-chloro-4-ethoxydiphenylmethane Q: What is the CAS Number of 5-bromo-2-chloro-4-ethoxydiphenylmethane Q: What is the storage condition of 5-bromo-2-chloro-4-ethoxydiphenylmethane Q: What are the applications of 5-bromo-2-chloro-4-ethoxydiphenylmethane Benzene, 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]- Dapagliflozin Bromo impurity 4-bromo-1-chloro-2-[(4-ethoxyphenyl)methyl]benzene Dapagliflozin Intermediate/ 5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane 4-(5- bromo -2- chlorobenzyl) phenethyl ether 5-Bromo-2-chIoro-4’-ethoxydiphenyImethane 4-Bromo-1-ChIoro 2-4-EthoxybenzyI-Benzene 4-bromo-l-chloro-2-(4-ethoxybenzyl)benzene 2-(4-ethoxybenzyl)-4-bromo-1-chloro benzene 5-bromo-2-chloro-4’-ethoxydiphenylmethane, Or 4-(5-Bromo-2-chlorobenzyl)phenyl ethyl ether (5-Bromo-2-chlorobenzyl)phenyl ethyl ether 5-bromo-2-chloro-4'-ethoxydiphenylmethane 6-bromo-2-chloro-4’-ethoxydiphenylmethane 4-Bromo-1-chloro-2-(4-ethoxybenzyl)benzene 461432-23-5 61432-23-5 100134-06-9 9461432-23-5 C15H14BrClO Halides Phenyls & Phenyl-Het 461432-23-5 ADVANCED INT.