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Description References
1,3-Butanediol structure
Chemical Name:
Molecular Formula:
Formula Weight:
MOL File:

1,3-Butanediol Properties

Melting point:
-54 °C
Boiling point:
203-204 °C(lit.)
1.005 g/mL at 25 °C(lit.)
vapor density 
3.1 (20 °C, vs air)
vapor pressure 
0.06 mm Hg ( 20 °C)
refractive index 
n20/D 1.44(lit.)
Flash point:
250 °F
storage temp. 
Clear colorless to yellow, may discolor to brown on storage
6.1 (500g/l, H2O, 20℃)
explosive limit
Water Solubility 
Stable. Flammable. Hygroscopic - protect from air and moisture. Incompatible with strong oxidizing agents.
CAS DataBase Reference
107-88-0(CAS DataBase Reference)
NIST Chemistry Reference
EPA Substance Registry System
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Safety Statements  24/25
WGK Germany  1
RTECS  EK0440000
Autoignition Temperature 741 °F
HS Code  29053920
Hazardous Substances Data 107-88-0(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: 18610 mg/kg LD50 dermal Rabbit > 20000 mg/kg
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

1,3-Butanediol price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 09068 (±)-1,3-Butanediol analytical standard 107-88-0 5ml $201 2018-11-13 Buy
Sigma-Aldrich 09068 (±)-1,3-Butanediol analytical standard 107-88-0 1ml $51.5 2018-11-13 Buy
TCI Chemical B0679 1,3-Butanediol >99.0%(GC) 107-88-0 25g $12 2018-11-22 Buy
TCI Chemical B0679 1,3-Butanediol >99.0%(GC) 107-88-0 500g $24 2018-11-22 Buy
Alfa Aesar A11684 (±)-1,3-Butanediol, 99% 107-88-0 500ml $34.4 2018-11-15 Buy

1,3-Butanediol Chemical Properties,Uses,Production


1,3-Butanediol is an organic chemical which belongs to the family of secondary alcohols. At present, 1,3-butanediol is used mainly in surfactants, inks, solvents for natural and synthetic flavoring agents and serves as a co-monomer in manufacturing certain polyurethane and polyester resins. It can also serve as a humectant to prevent loss of moisture in cosmetics, particularly in hair sprays and setting lotions. Besides, 1,3-Butanediol is pharmaceutically involved in the production of colchicine derivatives as a anticancer agent and in the synthesis of dual peroxisome proliferator-activated gamma and delta agonists acting as a hypoglycaemic agent, which is effective for the treatment of diabetes.


Chemical Properties

colourless liquid

Chemical Properties

Butylene glycol occurs as a clear, colorless, viscous liquid with a sweet flavor and bitter aftertaste.


1,3-Butanediol is used in the synthesis of colchicine derivatives as anticancer agents. Also used in the synthesis of dual peroxisome proliferator-activated gamma and delta agonists acting as euglycem ic agents in the treatment of diabetes.


Its most extensive use is as an intermediate in the manufacture of polyester plasticisers and other chemical products. It finds some use as a solvent and humectant, a useful chemical intermediate. It has extensive application in the manufacture of structural materials for boats, custom mouldings, and sheets and boards for construction applications. 1,3-Butanediol imparts resistance to weathering plus flexibility and impact resistance. It is also used in the manufacture of saturated polyesters for polyurethane coatings, where the glycol imparts greater flexibility to the polyester molecule. 1,3-Butanediol is currently used in many personal care products.


ChEBI: A butanediol compound having two hydroxy groups in the 1- and 3-positions.

Production Methods

Butylene glycol is prepared by catalytic hydrogenation of aldol using Raney nickel.

Pharmaceutical Applications

Butylene glycol is used as a solvent and cosolvent for injectables. It is used in topical ointments, creams, and lotions, and it is also used as a vehicle in transdermal patches. Butylene glycol is a good solvent for many pharmaceuticals, especially estrogenic substances.
In an oil-in-water emulsion, butylene glycol exerts its best antimicrobial effects at ~8% concentration. Higher concentrations above 16.7% are required to inhibit fungal growth.

Contact allergens

This dihydric alcohol is used for its humectant and preservative potentiator properties in cosmetics, topical medicaments and polyurethane, polyester, cellophane, and cigarettes. It has similar properties, but is less irritant than propylene glycol. Contact allergies seem to be rare.

Safety Profile

Mdly toxic by ingestion and subcutaneous routes. A skin and eye irritant. See also ETHYLENE GLYCOL. Experimental reproductive effects. Combustible when exposed to heat or flame. Incompatible with oxidizing materials. To fight fire, use foam, alcohol foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes.


Butylene glycol is used in a wide variety of cosmetic formulations and is generally regarded as a relatively nontoxic material. It is mildly toxic by oral and subcutaneous routes.
In topical preparations, butylene glycol is regarded as minimally irritant. Butylene glycol can cause allergic contact dermatitis, with local sensitivity reported in patch tests. Some local irritation is produced on eye contact.
LD50 (guinea pig, oral): 11.0 g/kg
LD50 (mouse, oral): 12.98 g/kg
LD50 (rat, oral): 18.61 g/kg
LD50 (rat, SC): 20.0 g/kg


Butylene glycol is hygroscopic and should be stored in a well-closed container in a cool, dry, well-ventilated place. When heated to decomposition, butylene glycol emits acrid smoke and irritating fumes.


Butylene glycol is incompatible with oxidizing reagents.

Regulatory Status

GRAS listed. Included in the FDA Inactive Ingredients Database (transdermal patches). Included in licensed medicines in the UK (topical gel patches/medicated plasters).

1,3-Butanediol Preparation Products And Raw materials

Raw materials

Preparation Products

1,3-Butanediol Suppliers

Global( 247)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 CHINA 3217 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 22043 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32651 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825 CHINA 2464 55
Jiangsu Qingquan Chemical Co., Ltd.
+86-571-86589381/86589382/86589383 CHINA 177 55
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254 CHINA 20229 58
Haihang Industry Co.,Ltd
+86 531 8582 1093 CHINA 4557 58
career henan chemical co
+86-371-86658258 CHINA 19997 58
Kono Chem Co., Ltd
+86-132 8924 6953 CHINA 2164 58

View Lastest Price from 1,3-Butanediol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-23 1,3-Butanediol
US $1.00 / kg 1kg 95%-99% as request career henan chemical co

1,3-Butanediol Spectrum

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