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Dibutylamine

Dibutylamine
Dibutylamine structure
CAS No.
111-92-2
Chemical Name:
Dibutylamine
Synonyms
DNBA;ai3-15329;ai3-52649;Dibutylamin;(n-C4H9)2NH;DIBUTYLAMINE;Dibutilamina;Dibuthylamine;Di-n-butylamin;N-DIBUTYLAMINE
CBNumber:
CB8416375
Molecular Formula:
C8H19N
Formula Weight:
129.24
MOL File:
111-92-2.mol

Dibutylamine Properties

Melting point:
−62 °C(lit.)
Boiling point:
159 °C(lit.)
Density 
0.767 g/mL at 25 °C(lit.)
vapor density 
4.46 (vs air)
vapor pressure 
1.9 mm Hg ( 20 °C)
refractive index 
n20/D 1.417(lit.)
Flash point:
106 °F
storage temp. 
Flammables area
solubility 
water: soluble3.8g/L at 20°C
pka
11.25(at 21℃)
form 
Liquid
color 
White
PH
11.1 (1g/l, H2O, 20℃)
Odor
Weak ammonia.
explosive limit
0.6-6.8%(V)
Water Solubility 
4.05 g/L (25 ºC)
Merck 
14,3032
BRN 
506001
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents, most common metals, strong acids. Vapours may flow over surfaces to a distant source of ignition. Can form explosive mixtures with air.
CAS DataBase Reference
111-92-2(CAS DataBase Reference)
NIST Chemistry Reference
1-Butanamine, N-butyl-(111-92-2)
EPA Substance Registry System
1-Butanamine, N-butyl-(111-92-2)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
  • NFPA
Hazard Codes  Xn,T
Risk Statements  10-20/21/22-35-23-21/22
Safety Statements  45-36/37/39-28A-26-23
RIDADR  UN 2248 8/PG 2
WGK Germany  1
RTECS  HR7780000
10
Autoignition Temperature 594 °F
TSCA  Yes
HS Code  2921 19 99
HazardClass  8
PackingGroup  II
Hazardous Substances Data 111-92-2(Hazardous Substances Data)
Toxicity LD50 orally in rats: 550 mg/kg (Smyth)
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H226 Flammable liquid and vapour Flammable liquids Category 3 Warning
H290 May be corrosive to metals Corrosive to Metals Category 1 Warning P234, P390, P404
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H311 Toxic in contact with skin Acute toxicity,dermal Category 3 Danger P280, P302+P352, P312, P322, P361,P363, P405, P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H330 Fatal if inhaled Acute toxicity,inhalation Category 1, 2 Danger P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
H401 Toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 2 P273, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P234 Keep only in original container.
P240 Ground/bond container and receiving equipment.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P310 Immediately call a POISON CENTER or doctor/physician.
P320 Specific treatment is urgent (see … on this label).
P390 Absorb spillage to prevent material damage.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P307+P311 IF exposed: call a POISON CENTER or doctor/physician.
P370+P378 In case of fire: Use … for extinction.
P405 Store locked up.

NFPA 704

Diamond Hazard Value Description
2
0
Health  
Flammability   2 Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur)
Instability   0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
Special  

(NFPA, 2010)

Dibutylamine price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 34490 Dibutylamine puriss., ≥99.0% (GC) 111-92-2 500ml-f $33.5 2018-11-13 Buy
Sigma-Aldrich 471232 Dibutylamine ≥99.5% 111-92-2 1l $69.5 2018-11-13 Buy
TCI Chemical D0218 Dibutylamine >99.0%(GC)(T) 111-92-2 25mL $18 2018-11-22 Buy
TCI Chemical D0218 Dibutylamine >99.0%(GC)(T) 111-92-2 500mL $30 2018-11-22 Buy
Alfa Aesar A11671 Di-n-butylamine, 98+% 111-92-2 500ml $31.4 2018-11-13 Buy

Dibutylamine Chemical Properties,Uses,Production

Chemical Properties

colourless liquid with an amine odour

Chemical Properties

Dibutylamine is a colorless liquid with an odor of ammonia.

Chemical Properties

n-Dibutylamine is a strong base and undergoes reactions with acids. It reacts with carbon disulfide and carbon dioxide to form alkyl ammonium salts of dithiocarbamic acid and carbamic acid, respectively.
n-Dibutylamine is nitrosated by nitrite at low pHs to form the mutagenic and carcinogenic product, N-nitrosodibutylamine (Sithole and Guy 1986).

Production Methods

n-Dibutylamine is prepared by two major methods. The first involves passing ammonia and butanol over an alumina or silica catalyst at a temperature of 300-500°C and under pressure. The second method employs passing ammonia, butanol, and hydrogen over a dehydrogenation catalyst. In each instance the resulting mixtures are separated by continuous distillation and extraction (Schweizer et al 1978). n-Dibutylamine can also be prepared from butyl bromide and ammonia or by reaction of butyl chloride and ammonia (HSDB 1989). The amine also is naturally present in food (Neurath et al 1977) and its emissions are produced in soil and sewage. The amine is also found in the expired air of normal, healthy, nonsmoking adults (Krotoszynski et al 1979).
N-Nitrosamines and their precursors including n-dibutylamine are present in rubber products in which the accelerators and stabilizers used in the vulcanization process were derived from dialkylamines. Analysis of a single extraction of rubber nipples and baby pacifiers with artificial saliva (containing sodium nitrite) showed n-dibutylamine levels up to 3890 p.p.b. and N-nitrosodibutylamine concentrations as high as 427 p.p.b. (Thompson et al 1984).

General Description

A yellow-colored liquid with a amine-like odor. Denser than water. Very corrosive, may burn skin, eyes, and mucous membranes. Flash point 125°F. Combustible. Produce toxic oxides of nitrogen when burned. Used to make other chemicals.

Air & Water Reactions

Flammable. Soluble in water.

Reactivity Profile

Dibutylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

Inhalation causes irritation of nose, throat, and lungs; coughing; nausea; headache. Ingestion causes irritation of mouth and stomach. Contact with eyes causes irritation. Contact with skin causes irritation and dermatitis.

Health Hazard

n-Dibutylamine is a severe irritant to skin and mucous membranes of the nose, eyes, and respiratory tract. Exposure to this amine may result in some activation of the sympathetic branch of the autonomic nervous system as manifested by elevated blood pressure, eye pupil dilation and flushing of the skin.

Fire Hazard

Flash Point (°F): 125 ℃; Flammable Limits in Air (%): 1.1 (LFL); Fire Extinguishing Agents: "Alcohol" foam, dry chemical, carbon dioxide; Fire Extinguishing Agents Not To Be Used: Water may be ineffective; Special Hazards of Combustion Products: Toxic oxides of nitrogen may form in fires; Behavior in Fire: Data not available; Ignition Temperature: Data not available; Electrical Hazard: Data not available; Burning Rate: 5.84 mm/min.

Fire Hazard

Special Hazards of Combustion Products: Toxic oxides of nitrogen may form in fires.

Chemical Reactivity

Reactivity with Water No reaction; Reactivity with Common Materials: May corrode some metals and attack some forms of plastics; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Industrial uses

Primary industrial uses of n-dibutylamine include flotation reagents, dyestuffs, rubber vulcanization accelerators, and corrosion inhibitors (HSDB 1989). In 1985 US production totalled approximately 2000 tons.

Safety Profile

Poison by ingestion and subcutaneous routes. Moderately toxic by skin contact and inhalation. Corrosive. A severe skin and eye irritant. Mutation data reported. Flammable liquid when exposed to heat or flame; can react with oxidizing materials. To fight fire, use alcohol foam, foam, CO2, dry chemical. Exothermic reaction with cellulose nitrate does not proceed to ignition. When heated to decomposition it emits toxic fumes of NOx.

Potential Exposure

Used as a corrosion inhibitor; and intermediate for emulsifiers, rubber products, dyes; and insecticides.

First aid

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, includ- ing resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. If victim is conscious, administer water or milk. Do not induce vomiting. Medical observation is recommended for 24 to 48 hours after breathing overexpo- sure, as pulmonary edema may be delayed. As first aid for pulmonary edema, a doctor or authorized paramedic may consider administering a drug or other inhalation therapy.

Metabolism

There is little information available on the absorption, distribution and metabolism of ra-dibutylamine. Aliphatic amines such as dibutylamine are well absorbed from the gut. Both monoamine oxidase and diamine oxidase, which are present in most tissues, are capable of metabolizing many exogenous amines. Although the metabolism of primary amines is more rapid than secondary, the rate of oxidation by the enzyme increases with chain length of the amine, reaching a maximum of five carbon atoms (Beard and Noe 1981). Therefore, n-dibutylamine may be metabolized by these enzyme systems although definitive evidence is lacking.
The highly carcinogenic and mutagenic N-nitrosodibutylamine is formed by reaction of nitrite with n-dibutylamine, the highest rates of nitrosation occurring at low pH (Sithole and Guy 1986). The n-dibutylamine present in ingested foods is nitrosated in the stomach by endogenous nitrite from saliva, etc. together with the sodium nitrite present in some preserved foods to form the highly toxic Nnitrosamine (Airoldi et al 1987). Food additives such as butylated hydroxyanisole inhibited in vitro the nitrosation of n-dibutylamine but this inhibition was not seen in vivo in rats that were given both n-dibutylamine and sodium nitrite.
The endogenous formation of N-nitrosodibutylamine was studied in rats after administration of sodium nitrite or sodium nitrate and n-dibutylamine (Airoldi et al 1984). Urinary excretion of N-nitrosodibutylamine and its metabolites N-butyl- N-(4-hydroxybutyl)-nitrosamine (BBN) and N-butyl-N-(3-carboxypropyl)nitrosamine (BCPN) than was determined. Rats were supplied with 0.2% sodium nitrite or 0.5% sodium nitrate in drinking water and given n-dibutylamine by gavage at 3 doses of 50 mg/kg, 8 h apart. Analysis of the 24 h urine by GC equipped with a thermal energy analyzer failed to detect N-nitrosodibutylamine or its metabolite BBN. However, BCPN was found in the urine of both the sodium nitrite and sodium nitrate groups, indicating that in vivo nitrosation of n-dibutylamine had occurred.

Shipping

UN2248 Di-n-butylamine, Hazard class: 8; Labels: 8-Corrosive material, 3-Flammable liquid.

Purification Methods

Dry this strong base with LiAlH4, CaH2 or KOH pellets, filter and distil it from BaO or CaH2. [Beilstein 4 IV 550.]

Incompatibilities

May form explosive mixture with air. Aqueous solution is a strong base. Incompatible with acids, acid chlorides; acid anhydrides; halogens, isocyanates, vinyl acetate; acrylates, substituted allyls; alkylene oxides, epichlorohydrin, ketones, aldehydes, alcohols, gly- cols, phenols, cresols, caprolactum solution; strong oxidi- zers; reactive organic compounds. Attacks copper alloys, zinc, tin, tin alloys; galvanized steel. Also, carbon dioxide is listed as incompatible by the state of New Jersey.

Waste Disposal

Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.

Dibutylamine Preparation Products And Raw materials

Raw materials

Preparation Products


Dibutylamine Suppliers

Global( 212)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21990 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114
sales@amoychem.com CHINA 6374 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24001 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20095 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 4669 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 19923 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 021-20337333/400-620-6333
021-50323701 sale@aladdin-e.com China 24991 65
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76

View Lastest Price from Dibutylamine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-21 Dibutylamine
111-92-2
US $7.00 / kg 1kg 99% 100kg career henan chemical co

Dibutylamine Spectrum


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