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Clostebol

CAS No.
1093-58-9
Chemical Name:
Clostebol
Synonyms
CLOSTEBOL;Cholostebol;17β-Clostebol;Chlortestosterone;Clostebol VETRANAL;Clostebol Standard;Clostebol USP/EP/BP;C11691600 Clostebol;ClostebolAcetateBase;4-CHLOROTESTOSTERONE
CBNumber:
CB8730750
Molecular Formula:
C19H27ClO2
Molecular Weight:
322.87
MDL Number:
MFCD00198396
MOL File:
1093-58-9.mol
MSDS File:
SDS
Last updated:2023-05-04 17:41:45

Clostebol Properties

Melting point 188-190°
alpha D20 +148° (CHCl3)
Boiling point 448.4±45.0 °C(Predicted)
Density 1.0514 (estimate)
solubility DMF: 20 mg/mL; DMSO: 30 mg/mL; DMSO:PBS (pH 7.2) (1:10): 0.09 mg/mL; Ethanol: 20 mg/mL
form A crystalline solid
pka 14.99±0.70(Predicted)
CAS DataBase Reference 1093-58-9(CAS DataBase Reference)
FDA UNII Z7D4G976SH
NIST Chemistry Reference 4-Chloro-17beta-hydroxyandrost-4-en-3-one(1093-58-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Warning
Hazard statements  H351
Precautionary statements  P201-P202-P281-P308+P313-P405-P501
Hazard Codes  Xn
Risk Statements  40
Safety Statements  36/37
DEA Controlled Substances CSCN: 4000
CSA SCH: Schedule III
NARC: No

Clostebol price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 21168 Clostebol ≥98% 1093-58-9 1mg $44 2024-03-01 Buy
Cayman Chemical 21168 Clostebol ≥98% 1093-58-9 5mg $109 2024-03-01 Buy
AK Scientific 4111CA Clostebol 1093-58-9 1mg $147 2021-12-16 Buy
American Custom Chemicals Corporation SHG0004763 CLOSTEBOL 95.00% 1093-58-9 10MG $750.75 2021-12-16 Buy
American Custom Chemicals Corporation SHG0004763 CLOSTEBOL 95.00% 1093-58-9 100MG $1963.5 2021-12-16 Buy
Product number Packaging Price Buy
21168 1mg $44 Buy
21168 5mg $109 Buy
4111CA 1mg $147 Buy
SHG0004763 10MG $750.75 Buy
SHG0004763 100MG $1963.5 Buy

Clostebol Chemical Properties,Uses,Production

Description

Clostebol (Item No. 21168) is an analytical reference standard that is categorized as an androgenic anabolic steroid. Clostebol is a chlorinated form of testosterone (Item Nos. 15645 | ISO60154) that has been used as an athletic performance enhancer and to fatten cattle. It is also detectible in urine. Formulations containing clostebol have been used to treat osteoporosis, anorexia, and certain types of liver disease. Clostebol is regulated as a Schedule III compound in the United States. This product is intended for research and forensic applications.

Uses

Clostebol is an anabolic steroid. This is a controlled substance.

Definition

ChEBI: Clostebol is a 3-hydroxy steroid. It has a role as an androgen.

Synthesis

Clostebol can be synthesized from 4,5-Epoxy-androstan-17β-ol-3-one by acidification with 25% hydrochloric acid.
Procedure:8.50 g epoxide (4,5-Epoxy-androstan-17β-ol-3-one) was dissolved in 150 ml Acetone and treated with 14 ml of 25% hydrochloric acid. An immediate color shift of the reaction mixture from light yellow to deep blue can be observed. After stirring for 30 h at room temperature, a complete conversion of the epoxide (4,5-Epoxy-androstan-17β-ol-3-one) can be monitored by TLC. The reaction mixture was diluted with 400 ml water, leading to the formation of a blue-black solid precipitating from the solution. After evaporation of acetone, the remaining aqueous solution was extracted several times with 200 ml dichloromethane. The combined organic extracts were washed with saturated sodium bicarbonate solution and sodium chloride solution before drying over magnesium sulfate. The crude product was chromatographed on silica gel by using hexane-ethyl acetat (1:1) and followed by a recrystallization from acetone. The isolated product Clostebol was obtained as yellowish crystals (4.50 g; 51%).

Clostebol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Chloro-17beta-hydroxyandrost-4-en-3-one Androst-4-en-3-one, 4-chloro-17-hydroxy-, (17beta)- 4-ANDROSTEN-4-CHLORO-17-BETA-OL-3-ONE 4-CHLOROTESTOSTERONE 4-CHLOROTESTOSTERONE ALCOHOL CLOSTEBOL Clostebol VETRANAL ClostebolAcetateBase 4-Chloro-17b-hydroxy-4-androsten-3-one 4-Chloro-17β-hydroxy-4-androsten-3-one, 4-Chlorotestosterone Androst-4-en-3-one, 4-chloro-17-hydroxy-, (17b)- 17β-Clostebol 17β-Hydroxy-4-chloroandrosta-4-ene-3-one 4-Chloro-17β-hydroxyandrost-4-en-3-one Chlortestosterone Cholostebol Chlorotestosteronum acetate (8R,9S,10R,13S,14S,17S)-4-chloro-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one (17β)-4-Chloro-17-hydroxyandrost-4-en-3-one 4-Chloro-3-oxo-17β-hydroxyandrost-4-ene Clostebol Solution, 100ppm Clostebol Acetate Impurity 1 Clostebol Standard Androst-4-en-3-one, 4-chloro-17-hydroxy-, (17β)- Clostebol USP/EP/BP Clostebol Raw Powder 4-ANDROSTEN-4-CHLORO-17β-OL-3-ONE C11691600 Clostebol Clostebol 100 μg/ml Acetonitrile 1093-58-9 C19H27ClO2 Steroid and Hormone