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Ambroxol

Ambroxol
Ambroxol structure
CAS No.
18683-91-5
Chemical Name:
Ambroxol
Synonyms
Pect;NA-872;Motosol;Mucofar;Mucosan;AMBROXOL;Fluibron;Lindoxyl;Solvolan;Sufactal
CBNumber:
CB9186114
Molecular Formula:
C13H18Br2N2O
Formula Weight:
378.1
MOL File:
18683-91-5.mol

Ambroxol Properties

Melting point:
233-234 C
Boiling point:
468.6±45.0 °C(Predicted)
Density 
1.5863 (rough estimate)
refractive index 
1.6220 (estimate)
storage temp. 
2-8°C
pka
15.12±0.40(Predicted)
CAS DataBase Reference
18683-91-5(CAS DataBase Reference)
FDA UNII
200168S0CL
NIST Chemistry Reference
Ambroxol(18683-91-5)
SAFETY
  • Risk and Safety Statements
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  36-26
WGK Germany  3
RTECS  GV8423000

Ambroxol price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 19377 Ambroxol ≥98% 18683-91-5 25mg $29 2018-11-19 Buy
Cayman Chemical 19377 Ambroxol ≥98% 18683-91-5 50mg $49 2018-11-19 Buy
Cayman Chemical 19377 Ambroxol ≥98% 18683-91-5 100mg $93 2019-12-02 Buy

Ambroxol Chemical Properties,Uses,Production

Originator

Mucosolvan,Thomae,W. Germany,1980

Uses

expectorant

Manufacturing Process

6.5 g of N-(trans-p-hydroxycyclohexyl)-(2-aminobenzyl)-amine were dissolved in a mixture of 80 cc of glacial acetic acid and 20 cc of water, and then 9.6 g of bromine were added dropwise at room temperature while stirring the solution. After all of the bromine had been added, the reaction mixture was stirred for two hours more and was then concentrated in a water aspirator vacuum. The residue was taken up in 2 N ammonia, the solution was extracted several times with chloroform, and the organic extract solutions were combined and evaporated. The residue, raw N-(trans-phydroxycyclohexyl)-( 2-amino-3,5-dibromobenzyl)-amine, was purified with chloroform and ethyl acetate over silica gel in a chromatographic column, the purified product was dissolved in a mixture of ethanol and ether, and the solution was acidified with concentrated hydrochloric acid. The precipitate formed thereby was collected and recrystallized from ethanol and ether, yielding N-(trans-p-hydroxycyclohexyl)-(2-amino-3,5-dibromobenzyl)-amine hydrochloride, MP 233-234.5°C (decomposition).

Therapeutic Function

Expectorant

Ambroxol Preparation Products And Raw materials

Raw materials

Preparation Products


Ambroxol Suppliers

Global( 159)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21842 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22625 55
Hebei Chishuo Biotechnology Co., Ltd.
13292891350 +86 311 66567340
luna@speedgainpharma.com CHINA 1007 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30039 58
Zhonglan Industry Co., Ltd.
(86) 531-82956570
(86) 531-82956571 sales@zhonglanindustry.com CHINA 4895 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35434 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com CHINA 47486 58
Shaanxi Dideu Medichem Co. Ltd
18192627656
+86-29-88380327 1012@dideu.com CHINA 3899 58
Zhuozhou Wenxi import and Export Co., Ltd
+8613111626072
+8613111626072 zzwenxi@126.com CHINA 7527 58
SIMAGCHEM CORP
13806087780 +86 13806087780
shaobowang@simagchem.com CHINA 17852 58

View Lastest Price from Ambroxol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-04-24 Ambroxol
18683-91-5
US $0.01-1.00 / KG 1KG 99% 50 tons Shaanxi Dideu Medichem Co. Ltd
2019-07-11 Ambroxol
18683-91-5
US $1.00 / KG 1KG 99% 1ton career henan chemical co
2018-08-20 Ambroxol
18683-91-5
US $1.00 / KG 1G 98% 100KG career henan chemical co

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