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Ambroxol

Ambroxol
Ambroxol structure
CAS No.
18683-91-5
Chemical Name:
Ambroxol
Synonyms
Pect;NA-872;Motosol;Mucofar;Mucosan;AMBROXOL;Fluibron;Lindoxyl;Solvolan;Sufactal
CBNumber:
CB9186114
Molecular Formula:
C13H18Br2N2O
Formula Weight:
378.1
MOL File:
18683-91-5.mol

Ambroxol Properties

Melting point:
233-234 C
Boiling point:
468.6±45.0 °C(Predicted)
Density 
1.5863 (rough estimate)
refractive index 
1.6220 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
pka
15.12±0.40(Predicted)
CAS DataBase Reference
18683-91-5(CAS DataBase Reference)
FDA UNII
200168S0CL
ATC code
R05CB06
NIST Chemistry Reference
Ambroxol(18683-91-5)
SAFETY
  • Risk and Safety Statements
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  36-26
WGK Germany  3
RTECS  GV8423000

Ambroxol price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 19377 Ambroxol ≥98% 18683-91-5 25mg $29 2021-12-16 Buy
Cayman Chemical 19377 Ambroxol ≥98% 18683-91-5 50mg $49 2021-12-16 Buy
TRC A575990 Ambroxol 18683-91-5 50mg $130 2021-12-16 Buy
Biosynth Carbosynth FA64052 Ambroxol 18683-91-5 2 g $150 2021-12-16 Buy
Biosynth Carbosynth FA64052 Ambroxol 18683-91-5 5 g $250 2021-12-16 Buy

Ambroxol Chemical Properties,Uses,Production

Originator

Mucosolvan,Thomae,W. Germany,1980

Uses

expectorant

Manufacturing Process

6.5 g of N-(trans-p-hydroxycyclohexyl)-(2-aminobenzyl)-amine were dissolved in a mixture of 80 cc of glacial acetic acid and 20 cc of water, and then 9.6 g of bromine were added dropwise at room temperature while stirring the solution. After all of the bromine had been added, the reaction mixture was stirred for two hours more and was then concentrated in a water aspirator vacuum. The residue was taken up in 2 N ammonia, the solution was extracted several times with chloroform, and the organic extract solutions were combined and evaporated. The residue, raw N-(trans-phydroxycyclohexyl)-( 2-amino-3,5-dibromobenzyl)-amine, was purified with chloroform and ethyl acetate over silica gel in a chromatographic column, the purified product was dissolved in a mixture of ethanol and ether, and the solution was acidified with concentrated hydrochloric acid. The precipitate formed thereby was collected and recrystallized from ethanol and ether, yielding N-(trans-p-hydroxycyclohexyl)-(2-amino-3,5-dibromobenzyl)-amine hydrochloride, MP 233-234.5°C (decomposition).

Therapeutic Function

Expectorant

Ambroxol Preparation Products And Raw materials

Raw materials

Preparation Products


Ambroxol Suppliers

Global( 170)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com China 22607 55
career henan chemical co
+86-0371-55982848
sales@coreychem.com China 29954 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com China 47498 58
Shaanxi Dideu Medichem Co. Ltd
18192627656
+86-29-88380327 1012@dideu.com CHINA 3949 58
Zhuozhou Wenxi import and Export Co., Ltd
+8613111626072 (WhatsApp)
Wechat: +8613111626072 Wickr me: waynehu zzwenxi@126.com CHINA 13187 58
SIMAGCHEM CORP
13806087780 +86 13806087780
shaobowang@simagchem.com CHINA 17384 58
Target Molecule Corp
18019718960 781-999-5354
marketing@targetmol.com United States 19231 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671
0551-65418697 sales@tnjchem.com CHINA 37441 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
13588875226 86-571-88216897、88216896
86-571-88216895 sales@hzclap.com CHINA 6469 58

View Lastest Price from Ambroxol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-11-10 Ambroxol
18683-91-5
US $10.00 / Kg/Bag 1Kg/Bag 99% 20 Tons Hebei Zhanyao Biotechnology Co. Ltd
2021-11-09 Ambroxol
18683-91-5
US $10.00 / Kg/Bag 1Kg/Bag 99% 20 Tons Hebei Zhanyao Biotechnology Co. Ltd
2021-10-20 Ambroxol
18683-91-5
US $70.00 / KG 1KG 99% 9000kg/per week Hebei Lingding Biological Technology Co., Ltd

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