2-ナフトール

2-ナフトール 化学構造式
135-19-3
CAS番号.
135-19-3
化学名:
2-ナフトール
别名:
2-ナフトール;ベーターナフトール;C.I.アゾイックカップリングコンポーネント1;2-ナフタレノール;ベタナフトール;C.I.デベロッパー5;β-ナフトール;ベータナフトール;2-ヒドロキシナフタレン;β-ヒドロキシナフタレン;2-ナフチルアルコール;アゾイックCC1;デベロッパーA;ナフタレン-2-オール;2-ナフタレンオール;2-ナフトル;β‐ナフト-ル;βナフトル;2‐ナフトール;2-ナフトール(Β-)
英語名:
2-Naphthol
英語别名:
naphthalen-2-ol;2-naphthalenol;2-HYDROXYNAPHTHALENE;BETA NAPTHOL;BETA-NAPHTHOL;2-Naphtol;β-Naphthol;B-NAPHTHOL;2-Naftol;BETA NAPHTHO
CBNumber:
CB9336283
化学式:
C10H8O
分子量:
144.17
MOL File:
135-19-3.mol
MSDS File:
SDS

2-ナフトール 物理性質

融点 :
120-122 °C(lit.)
沸点 :
285-286 °C(lit.)
比重(密度) :
1,28 g/cm3
蒸気密度:
4.97 (vs air)
蒸気圧:
10 mm Hg ( 145.5 °C)
屈折率 :
1.5762 (estimate)
闪点 :
153 °C
貯蔵温度 :
Store below +30°C.
溶解性:
メタノール:可溶1g/10mL、透明、無色~淡黄色
酸解離定数(Pka):
9.51(at 25℃)
外見 :
粉末、結晶または顆粒
色:
白い
酸塩基指示薬変色域(pH):
Non& uorescence (8.5) to blue & uorescence (9.5)
臭い (Odor):
かすかなフェノールのような匂い
水溶解度 :
1g/L(20℃)
極大吸収波長 (λmax):
226nm, 265nm, 275nm, 286nm, 320nm, 331nm
Merck :
14,6384
BRN :
742134
安定性::
安定。可燃性。粉塵は空気と爆発性混合物を形成する可能性があります。強力な酸化剤であるフェノールとは相容れない。
主な用途:
Display device, semiconductors, photoimaging materials, inks, toner, chalk, security paper, molding materials, tin plating method, rubber, adhesive, leather, detergent, hair dyes, antimitotic drug, anticancer agent, antiinflammatory agent, treatment of acne vulgaris (pimples) and other dermal ailments (rashes, scratches, blemishes, hair loss), disorders
InChIKey:
JWAZRIHNYRIHIV-UHFFFAOYSA-N
LogP:
1.89 at 20℃
CAS データベース:
135-19-3(CAS DataBase Reference)
NISTの化学物質情報:
2-Naphthalenol(135-19-3)
EPAの化学物質情報:
2-Naphthalenol (135-19-3)
安全性情報
  • リスクと安全性に関する声明
  • 危険有害性情報のコード(GHS)
主な危険性  Xn,N
Rフレーズ  20/22-50
Sフレーズ  24/25-61
RIDADR  UN 3077 9/PG 3
WGK Germany  2
RTECS 番号 QL2975000
8
自然発火温度 430 °C
TSCA  Yes
国連危険物分類  9
容器等級  III
HSコード  29071590
有毒物質データの 135-19-3(Hazardous Substances Data)
毒性 LD50 orally in Rabbit: 1960 mg/kg LD50 dermal Rabbit > 10000 mg/kg
化審法 (4)-355
PRTR法 第一種指定化学物質
毒劇物取締法 劇物
環境リスク評価 2-ナフトール(135-19-3)
絵表示(GHS) GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
注意喚起語 危険
危険有害性情報
コード 危険有害性情報 危険有害性クラス 区分 注意喚起語 シンボル P コード
H317 アレルギー性皮膚反応を起こすおそれ 感作性、皮膚 1 警告 GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H318 重篤な眼の損傷 眼に対する重篤な損傷性/眼刺激 性 1 危険 GHS hazard pictograms P280, P305+P351+P338, P310
H400 水生生物に強い毒性 水生環境有害性、急性毒性 1 警告 GHS hazard pictograms P273, P391, P501
注意書き
P273 環境への放出を避けること。
P280 保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。
P301+P312 飲み込んだ場合:気分が悪い時は医師に連絡する こと。
P302+P352 皮膚に付着した場合:多量の水と石鹸で洗うこと。
P305+P351+P338 眼に入った場合:水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

2-ナフトール 価格 もっと(36)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01AFAA14564 2-ナフトール, 98+%
2-Naphthol, 98+%
135-19-3 250g ¥11230 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01AFAA14564 2-ナフトール, 98+%
2-Naphthol, 98+%
135-19-3 1000g ¥29290 2024-03-01 購入
東京化成工業 N0027 2-ナフトール >99.0%(GC)
2-Naphthol >99.0%(GC)
135-19-3 25g ¥2600 2024-03-01 購入
東京化成工業 N0027 2-ナフトール >99.0%(GC)
2-Naphthol >99.0%(GC)
135-19-3 250g ¥8600 2024-03-01 購入
関東化学株式会社(KANTO) 18082-2A 2‐ナフトール
2‐Naphthol (2=β)
135-19-3 2.5kg ¥44800 2024-03-01 購入

2-ナフトール MSDS


Naphthyl alcohol

2-ナフトール 化学特性,用途語,生産方法

外観

白色〜うすい紅色, 結晶〜粉末

溶解性

エタノール及びジエチルエーテルに溶けやすく、水に極めて溶けにくい。

用途

医薬品原料、有機合成原料。

使用上の注意

空気中で次第に着色する。

化学的特性

2-Naphthol is a white, crystalline solid. Slight phenolic odor. Darkens in air and on exposure to light. 2-Naphthol [135-19-3] b-naphthol, 2- naphthalenol, 2-hydroxynaphthalene, C10H8O, Mr 144.16, forms colorless plates upon sublimation, which darken on exposure to air or light. Unlike 1-naphthol it is nonvolatile in steam. 2-Naphthol is reduced with sodium or with hydrogen in the presence of a catalyst to give mainly 1,2,3,4-tetrahydro-2-naphthol (unlike 1- naphthol which gives the arylphenol under the same conditions). Oxidation with ferric chloride forms 2,20 -dihydroxy-1,10 -binaphthyl, with any blue coloration indicating the presence of 1- naphthol. Air oxidation at 300℃ with a vanadium pentoxide catalyst also yields 1,10 -bi-2-naphthol, which dehydrates at higher temperature to the oxide and finally decomposes to give benzoic acid. Treatment with sulfuryl chloride in carbon disulfide or with NaOCl – NaOH leads to 1- chloro-2-naphthol, whereas chlorine in sodium carbonate gives 8-chloro-2-naphthol ( plus 1, 10 - bi-2-naphthol). Reaction with phosphorus pentachloride at 150℃ gives 2-chloronaphthalene or at lower temperature, tri-2-naphthyl phosphate (mp 111℃), which can be isolated after treatment of the reaction mixture with alkali. Reaction with one equivalent of bromine in acetic acid gives 1-bromo-2-naphthol, whereas excess bromine yields 1,6-dibromo-2-naphthol. The latter is readily debrominated in dilute mineral acid to yield 6-bromo-2-naphthol. Excess bromine reacts with 2-naphthol at 100℃ to form 1,5,6- tribromo- and 1,3,5,6-tetrabromo-2-naphthol.

使用

2-Naphthol is used in the manufacture of dyes, perfumes, and medicinal organics, and in the production of antioxidants for synthetic rubber.

製造方法

2-Naphthol is produced by caustic fusion of naphthalene-2-sulfonic acid. Typically, the sodium salt of the sulfonic acid is added gradually to 50 % sodium hydroxide liquor at 300℃; the melt is then heated further at 320℃ in a gas-fired iron vessel with vigorous agitation. After completion of the reaction, the melt is run into excess water, possibly including filtrate from the previous batch at a proven tolerable level, and the naphtholate solution is neutralized to pH 8 with dilute sulfuric acid. If the temperature is maintained at >100℃ during neutralization, the crude product comes out of solution as an oil, which is separated, washed with hot water, and distilled under vacuum to give pure 2-naphthol. The molten material is processed through a flaker to give the final product for packaging. The fusion yield is about 80 % of the theoretical value, resulting in an overall yield of 70 % based on naphthalene. Typical specifications for 2-naphthol are clear solution in dilute caustic soda,  mp 120.5℃, and 1-naphthol content<0.3 %.
The newer method of manufacture is economically and environmentally favored in the United States, because despite requiring three stages, it is more amenable to continuous operation with recycle streams. The alkylation and isomerization are carried out up to 240℃ with a phosphoric acid catalyst. Final catalytic oxidation at 90 – 110℃ gives the hydroperoxide, which is cleaved with dilute sulfuric acid to give 2-naphthol in high overall yield in spite of modest oxidation conversion.

定義

ChEBI: 2-naphthol is a naphthol carrying a hydroxy group at position 2. It has a role as an antinematodal drug, a genotoxin, a human xenobiotic metabolite, a mouse metabolite, a human urinary metabolite and a radical scavenger.

主な応用

It is used to produce Tobias acid, J acid, 2-hydroxy-3-naphthoic acid and azo dyes, and it is the raw material for rubber antioxidants, mineral dressing agents, fungicides, antiseptics, preservatives, etc.
As feed preservative. In China, it can be used for citrus preservation, the maximum dosage amount is 0.1 g/kg and the residue amount should be no more than 70 mg/kg.
2-Naphthol, also called ?-naphthol, 2-naphthalenol, is the intermediate for plant growth regulator, 2-naphthoxyacetic acid.
As analytic agent, absorbent of ethylene and carbon monoxide, and fluorescence indicator.
Important organic raw material and dye intermediate, used to produce Tobias acid, butyric acid, β-hydroxynaphthoic acid and used to produce N-phenyl-2-naphthylamine, Diafen NN and other antioxidant, organic pigments, and fungicides.
For the detection of bromine, chlorine, chlorate, niobium, copper, nitrite, and potassium. Substrate for fluorometric assay of phenol sulfotransferase. Acid and alkali indicator, dyes, organic synthesis, qualitative determination of allyl alcohol, methanol, chloroform, etc. Absorbent of carbon monoxide, ethanol, and fluorescence indicator. Determination of carbon monoxide, copper, nitrite, and potassium. Ethylene absorbent.

反応性

2-Naphthol is naphthalene homologues of phenol, with the hydroxyl group being more reactive than in the phenols.2-Naphthol converts to 2-naphthalenethiol by reaction with dimethylthiocarbamoyl chloride via the Newman–Kwart rearrangement.

一般的な説明

2-Naphthol (2OH) is a hydroxyarene molecule, which when electronically excited forms strong acid. Excited 2OH dissociates only in water. It has a slight phenolic odor. It is incompatible with strong oxidizing agents, strong bases, acid chlorides and acid anhydrides. It is one of the most commonly used fluorescence dye.

危険性

See α-naphthol

健康ハザード

Although the toxicity of 2-naphthol is of low order in test animals, ingestion of large amounts may result in nausea, vomiting, diarrhea, abdominal pain, convulsions, and hemolytic anemia. Death may result from respiratory failure. The oral LD50 value in rats is in the range 2000 mg/kg. 2-Naphthol is slightly more toxic than 1-naphthol [9015-3], the oral LD50 value of which is in the range 2500 mg/kg.
Skin contact can produce peeling of the skin and pigmentation.

火災危険

Noncombustible solid.

安全性プロファイル

Poison by ingestion, inhalation, and subcutaneous routes. Mutation data reported. A skin and eye irritant. Combustible when exposed to heat or flame. To fight fire, use CO2, dry chemical. Incompatible with antipyrine, camphor, phenol, ferric salts, menthol, potassium permanganate and other oxidzing materials, urethane.

職業ばく露

A potential danger to those involved in rubber antioxidant production, synthesis of dyes; leather processing; fungicides, pharmaceuticals, and perfumes. Used as an antioxidant for fats, oils; as an antiseptic; in insecticides.

概要

無色(または黄色)の結晶固体である。ナフタレンの水素を1個、ヒドロキシ基に置換した化合物で、フェノール類に分類される芳香族化合物である。ヒドロキシ基の置換位置が異なる異性体、1-ナフトールが存在する。化学工業ではβ-ナフトールと呼ばれている。

輸送方法

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard Class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.

純化方法

Crystallise 2-naphthol from aqueous 25% EtOH (charcoal), H2O, *benzene, toluene or CCl4. Alternatively, extract it repeatedly with small amounts of EtOH, followed by dissolution in a minimum volume of EtOH and precipitation with distilled water, then drying over P2O5 under vacuum. It has also been dissolved in aqueous NaOH and precipitated by adding acid (repeat several times), then precipitated from *benzene by addition of heptane. Final purification can be by zone melting or sublimation in vacuo. The 4-nitrobenzoate has m 104o (from EtOH). [Bardez et al. J Phys Chem 89 5031 1985, Kikuchi et al. J Phys Chem 91 574 1987, Beilstein 6 IV 4253.]

不和合性

Dust or powder may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, iron salts; 2,3-dimethyl-1- phenyl-3-pyrazolin-5-one (antipyrine); camphor, phenol, menthol, urethane.

廃棄物の処理

Mix with flammable solvent and atomize into an incinerator.

2-ナフトール 上流と下流の製品情報

原材料

準備製品


2-ナフトール 生産企業

Global( 801)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
SIMAGCHEM CORP
+86-13806087780
sale@simagchem.com China 17367 58
Hebei Mojin Biotechnology Co., Ltd
+8613288715578
sales@hbmojin.com China 12468 58
Hebei Dangtong Import and export Co LTD
+8615632927689
admin@hbdangtong.com China 984 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652
info@fdachem.com China 18222 58
hebei hongtan Biotechnology Co., Ltd
+86-86-1913198-3935 +8617331935328
sales03@chemcn.cn China 952 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618740459177
sarah@tnjone.com China 1142 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
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Capot Chemical Co.,Ltd.
571-85586718 +8613336195806
sales@capotchem.com China 29797 60
Dalian Richfortune Chemicals Co., Ltd
0411-84820922 8613904096939
sales@richfortunechem.com China 304 57
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21689 55


135-19-3(2-ナフトール)キーワード:


  • 135-19-3
  • c.i.37500
  • c.i.azoiccouplingcomponent1
  • c.i.developer5
  • Developer A
  • Developer AMS
  • Developer BN
  • developera
  • developerams
  • developerbn
  • naphthyl hydroxide
  • Naphthyl alcohol
  • NAPHTHOL, B-
  • iso-Napthol
  • 2-naphthol (beta)
  • Beta Naphthol (2-Naphthol)
  • B-NAPHTOL
  • BETA NAPHTHOL 99% MIN
  • 2-NAPHTHOL (BETA), FOR ANALYTICAL PURPOS ES
  • 2-NAPHTHOL R. G., REAG. PH. EUR.
  • 2-NAPHTHOL POWDER
  • 2-NAPHTHOL (BETA), FLUORESCENCE INDICATO R
  • betaNaphthol, Low Naphthalene
  • 2-NaphtholA.R.
  • 2-NaphtholGr
  • 2-NaphtholForSynthesis
  • BetaNaphthol99%
  • 2-Naphthol, 97+%
  • β-Monoxynaphthalene
  • 2-Naphthol, 99+%
  • 2-Naphthol, tech., 97%
  • 2-ナフトール
  • ベーターナフトール
  • C.I.アゾイックカップリングコンポーネント1
  • 2-ナフタレノール
  • ベタナフトール
  • C.I.デベロッパー5
  • β-ナフトール
  • ベータナフトール
  • 2-ヒドロキシナフタレン
  • β-ヒドロキシナフタレン
  • 2-ナフチルアルコール
  • アゾイックCC1
  • デベロッパーA
  • ナフタレン-2-オール
  • 2-ナフタレンオール
  • 2-ナフトル
  • β‐ナフト-ル
  • βナフトル
  • 2‐ナフトール
  • 2-ナフトール(Β-)
  • 2-ナフトール, 98+%
  • ナフトール, B-
  • 2 - ナフトール
  • 2-ナフト-ル
  • ベータ-ナフトール
  • キヒコートE
  • キヒテープ
  • 発色剤および関連製品
  • 機能性材料
  • 顕色剤
  • 忌避剤
  • 殺虫剤
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