PERHEXILINE MALEATE SALT
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PERHEXILINE MALEATE SALT 속성
- 녹는점
- 181-183°C
- 저장 조건
- 2-8°C
- 용해도
- DMSO: ≥5mg/mL
- 물리적 상태
- 가루
- 색상
- 흰색에서 황갈색까지
안전
| WGK 독일 | 2 | ||
|---|---|---|---|
| RTECS 번호 | TM7068000 | ||
| 독성 | LD50 in rats, mice (g/kg): >7, 4.37 orally (Causa, Perri) |
PERHEXILINE MALEATE SALT C화학적 특성, 용도, 생산
개요
Perhexiline is a carnitine palmitoyltransferase 1 (CPT1) and CPT2 inhibitor that was originally developed as an anti-anginal drug in the 1970s. It inhibits rat heart and liver CPT1 (IC50 = 77 and 148 μM, respectively) and rat heart CPT2 (IC50 = 79 μM). Inhibition of CPT reduces uptake of long-chain fatty acids into the mitochondria, thereby shifting cellular metabolism from β-oxidation to glycolysis. Perhexilin inhibits mTORC1 signaling at 10 μM and induces autophagy ~7-fold at a concentration of 10 μM in MCF-7 cells.화학적 성질
White Solid용도
PERHEXILINE MALEATE SALT is a Vasodilator, used in treatments for angina.일반 설명
Perhexiline maleate regulates?coronary vasodilatation and blocks exercise-induced tachycardia. It is used to treat angina pectoris and variant angina. Perhexiline maleate functions as a cardiac metabolic agent. It is associated with peripheral neuropathy, high intracranial pressure with?papilledema?and proximal myopathy.Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion.Human systemic effects by ingestion: muscle weakness, paresthesia, and hepatitis. Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx.PERHEXILINE MALEATE SALT 준비 용품 및 원자재
원자재
준비 용품
PERHEXILINE MALEATE SALT 공급 업체
글로벌( 81)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; |
laboratory@coreychem.com | China | 30255 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23556 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 |
1026@dideu.com | China | 9320 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 29220 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 |
sales@molcore.com | China | 49739 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 |
757984502@qq.com | China | 892 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 |
product@acmec-e.com | China | 33349 | 58 |
PERHEXILINE MALEATE SALT 관련 검색:
다우리신 부텐(2-)-1,4-디올
Piperacillin
Cefazolin sodium salt
Chlorphenamine maleate
CHLOROQUINE
Zolpidem tartrate
Quinidine
Trimebutine maleate
Enalapril maleate
PILSICAINIDE
1-(2,6-Dimethylphenoxy)-2-propanamine
PERHEXILINE MALEATE SALT
Ammonium hydrogen maleate
perhexiline
dicyclohexylmethane
3-CYCLOHEXYL-PROPYLAMINE
2-N-PROPYLPIPERIDINE