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Biperiden hydrochloride

Biperiden hydrochloride 구조식 이미지
카스 번호:
1235-82-1
상품명:
Biperiden hydrochloride
동의어(영문):
Bicamol;Akiriden;Tasmolin;NSC 84989;NSC 170950;BIPERIDINE HCL;Biperidene HCL;akinetonhydrochloride;BIPERIDEN HYDROCHLORIDE;biperidinehydrochloride
CBNumber:
CB2726050
분자식:
C21H30ClNO
포뮬러 무게:
347.92
MOL 파일:
1235-82-1.mol

Biperiden hydrochloride 속성

녹는점
238°
저장 조건
Desiccate at +4°C
용해도
DMSO: >20mg/mL
물리적 상태
powder
색상
off-white
NIST
Akineton, hydrochloride(1235-82-1)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn
위험 카페고리 넘버 22-R22
WGK 독일 3
RTECS 번호 TN3706000
독성 LD50 in rats, dogs (mg/kg): 750, 340 orally (Hanna)
그림문자(GHS):
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 P264, P270, P301+P312, P330, P501
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 P264, P280, P305+P351+P338,P337+P313P
예방조치문구:
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.

Biperiden hydrochloride C화학적 특성, 용도, 생산

화학적 성질

White Solid

용도

A muscarinic receptor antagonist

용도

Biperiden hydrochloride is antiparkinsonian; non-selective muscarinic receptor antagonist. Biperiden is used for the adjunctive treatment of all forms of Parkinson′s Disease (postencephalitic, idiopathic, and arteriosclerotic); also commonly used to improve parkinsonian signs and symptoms related to antipsychotic drug therapy.

용도

Antiparkinsonian;Anticholinergic

정의

ChEBI: The hydrochloride salt of biperiden. A muscarinic antagonist affecting both the central and peripheral nervous systems, it is used in the treatment of all forms of Parkinson's disease.

상표명

Akineton (Abbott).

일반 설명

Biperiden hydrochloride,α-5-norbornen-2-yl- -phenyl-1-piperidinepropanolhydrochloride (Akineton hydrochloride), is a white, opticallyinactive, crystalline, odorless powder that is slightlysoluble in water, ether, alcohol, and chloroform and sparinglysoluble in methanol.

생물학적 활성

Muscarinic receptor antagonist that displays some selectivity for the M 1 subtype (K i values are 0.48, 2.4, 3.9, 6.3 and 6.3 nM for M 1 , M 4 , M 3 , M 2 and M 5 receptors respectively). Alleviates extrapyramidal symptoms associated with antipsychotic drugs. Displays antiparkinsonian activity.

Clinical Use

Biperiden hydrochloride has all of the actions describedfor biperiden. The hydrochloride is used for tablets becauseit is better suited to this dosage form than is the lactate salt.As with the free base and the lactate salt, xerostomia (drynessof the mouth) and blurred vision may occur.

Biperiden hydrochloride 준비 용품 및 원자재

원자재

준비 용품


Biperiden hydrochloride 공급 업체

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+86 (0)571-858 647 95 sales@capotchem.com China 19919 60
Biochempartner
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J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
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3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15884 69
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32365 50
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123
86-21-63290778 86-21-63218885 sj_scrc@sinopharm.com China 9851 79
Jinan Haohua Industry Co., Ltd 0531-58773082 ;58773060
0531-58773099 sales@jnhaohua.com China 5587 58
Haoyuan Chemexpress Co., Ltd. 86-21-58998985
(86) 21-58955996 apisales@chemexpress.com.cn China 7560 61
AdooQ BioScience, LLC +1 (866) 930-6790
+1 (866) 333-9607 info@adooq.com United States 2774 58

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