마니톨

마니톨 C화학적 특성, 용도, 생산

용도

껌,캔디,쨈,젤리,간강보조식품.

개요

It can be used to lower intraocular pressure and in the postoperational period in ophthalomological procedures as well as during brain edema.

화학적 성질

D-mannitol (D-mannohexan-1.2.3.4.5.6-hexaol) is a constituent of several plants including the Manna ash, several edible plants, and seaweed. Parts of the latter contain up to 10 % mannitol by weight. The solubility in water is approximately 230 g/L at room temperature and it increases with increasing temperature. Mannitol is stable under the common processing conditions of foods.
Mannitol is approximately 50 % as sweet as sucrose and non-cariogenic. In the European Union, maltitol is approved as E 421 for a large number of food applications. In the United States, mannitol produced by hydrogenation of glucose or fructose solutions or by fermentation by Zygosaccharomyces rouxii or Lactobacillus intermedius is approved for several food applications. It is also approved in many other countries.

용도

Mannitol is a polyol (polyhydric alcohol) produced from hydrogena- tion from fructose that functions as a sweetener, humectant, and bulking agent. it has low hygroscopicity and poor oil solvency. it has 1.6 kcal/g. it is approximately 22% soluble in water and is approximately 72% as sweet as sugar, exhibiting a cool, sweet taste. it functions as a dusting agent with starch in chewing gum. it is used in sugarless candy, chewing gum, cereal, and pressed mints.

정의

mannitol: A polyhydric alcohol,CH₂OH(CHOH)₄CH₂OH, derived frommannose or fructose. It is the mainsoluble sugar in fungi and an importantcarbohydrate reserve in brownalgae. Mannitol is used as a sweetenerin certain foodstuffs and as a diureticto relieve fluid retention.

Mechanism of action

Today, mannitol is the most widely used osmotic diuretic. It raises osmotic pressure in renal tubules, thus reducing reabsorption of water in the nephrons. As a result, a large quantity of free water is released, sodium secretion increases, and as a rule, an insignificant amount of potassium is secreted. Mannitol is used as an adjuvant drug for preventing oliguria and anuriua.

Clinical Use

Mannitol is the agent most commonly used as an osmotic diuretic. Sorbitol also can be used for similar reasons.Mannitol is administered intravenously in solutions of 5 to 50% at a rate of administration that is adjusted to maintain the urinary output at 30 to 50 ml/hour. Mannitol is filtered at the glomerulus and is poorly reabsorbed by the kidney tubule. The osmotic effect of mannitol in the tubule inhibits the reabsorption of water, and the rate of urine flow can be maintained. It also is used to reduce intracranial pressure by reducing cerebral intravascular volume.

Safety Profile

A poison by intravenous route. Human systemic effects. When heated to decomposition it emits acrid smoke and irritating vapors.

마니톨 준비 용품 및 원자재

원자재

준비 용품

마니톨 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hebei Guanlang Biotechnology Co,.LTD	+8619930503252	daisy@crovellbio.com	China	5964	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Hebei Jingbo New Material Technology Co., Ltd	+8619931165850	hbjbtech@163.com	China	1000	58
Nanjing Deda New Material Technology Co., Ltd	+8613223293093	bella@njdeda.com	China	81	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	+8618740459177	sarah@tnjone.com	China	902	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	+8617702722807	admin@hbouhuang.com	China	2880	58
Sinoway Industrial co., ltd.	0592-5800732; +8613806035118	xie@china-sinoway.com	China	992	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55

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