Ketorolac
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Ketorolac 속성
- 녹는점
- 160-161°C
- 끓는 점
- 493.2±40.0 °C(Predicted)
- 밀도
- 1.33±0.1 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 3.49 ±0.02(at 25℃)
- 색상
- 회백색
- 수용성
- 183mg/L(32℃)
- CAS 데이터베이스
- 74103-06-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
유엔번호(UN No.) | 3249 | ||
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위험 등급 | 6.1(a) | ||
포장분류 | II | ||
HS 번호 | 2933998090 | ||
독성 | LD50 orally in mice: ~200 mg/kg (Rooks) |
Ketorolac C화학적 특성, 용도, 생산
화학적 성질
Light yellow solid용도
antiarrhythmicIndications
Ketorolac (Toradol), an NSAID chemically related to indomethacin and tolmetin, is mainly used as an analgesic, not for the treatment of inflammatory disease. It is available in oral, parenteral, and topical formulations.World Health Organization (WHO)
Ketorolac is a nonsteroidal anti-inflammatory agent used in the management of moderate to severe acute post-operative pain. It remains on the market in many countries with restrictions on its use.Biological Functions
Ketorolac (Toradol) is an NSAID with very mild antiinflammatory and antipyretic activity. It is a potent analgesic for postoperative pain. Its efficacy is equivalent to that of low doses of morphine in the control of pain. For this reason it is often combined with opioids to reduce opioid dose and related side effects while providing adequate pain relief. It is also used to replace the opioids in some patients with opioid sensitivity. The mechanism of action of ketorolac involves the inhibition of COX and decreased formation of prostaglandins. However, some evidence exists that ketorolac may stimulate the release of endogenous opioids as a part of its analgesic activity.일반 설명
Ketorolac tromethamine (Toradol), marketed as a mixture of(R)- and (S)-ketorolac enantiomers, is a potent NSAID analgesicindicated for the treatment of moderately severe, acutepain. It should be noted that the pharmacokinetic dispositionof ketorolac in humans is subject to marked enantioselectivity.Thus, it is important to monitor the individual blood levelsso an accurate assessment of its therapeutic action can bemade correctly. However, it should be noted that, beingone of the conventional NSAIDs with highest risk of GIcomplications, its administration should not exceed 5 days.Ketorolac 준비 용품 및 원자재
원자재
수소화나트륨
에탄올아민
노르말옥탄
무수초산
N,N-다이메틸폼아마이드
피롤
Bromoacetaldehyde
Acetylacetone
망간(II) 아세테이트 테트라하이드레이트
황화디메틸
N-클로로숙신이미드
플루탈산디메틸에스테르
과망간산칼륨
아세트산(빙초산)
Esterified product
2-Benzoylpyrrole
이염화에탄
Monoester
준비 용품
Ketorolac 공급 업체
글로벌( 250)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 |
qinhe02@xaltbio.com | China | 1000 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7845 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
Accela ChemBio Inc. | (+1)-858-699-3322 |
info@accelachem.com | United States | 19965 | 58 |
Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 |
info@edengenechem.com | China | 2169 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
Shanghai Longyu Biotechnology Co., Ltd. | +8615821988213 |
info@longyupharma.com | China | 2531 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49390 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-18612256290 |
1056@dideu.com | China | 3581 | 58 |
Ketorolac 관련 검색:
피롤
Ketorolac D5 P2
Ketorolac D5 P1
rac Ketorolac 6-Benzoyl IsoMer
Ketorolac EP IMpurity F
Ketorolac EP IMpurity I
1-Keto Ketorolac
Ketorolac Related Compound A (20 mg) (5-benzoyl-N-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)-2,3-dihydro-1H-pyrrolizine-1-carboxamide)
Ketorolac EP IMpurity H
Ketorolac EP IMpurity D
Ketorolac EP IMpurity G
Ketorolac-d5
Ketorolac tromethamine
Ketorolac
ACETOPHENONE-2',3',4',5',6'-D5
KETOROLAC TROMETAMOL FOR PEAK IDENTIFICATION
(R)-(+)-Ketorolac,(R)-Ketorolac
KETOROLAC