Standard

In the analysis work, it often demanded to apply high-quality compound with the exact content being accurate in order to be compared as the detection control or used to calibrate the instrument, the compound is known as standard sample.
Standard refers to the standard substance used for measuring the potency of biological products. When the production department submits to a higher authority for approval of the quality standard of the biological product, they should also provide the standard sample (indicated in unit (μ)) used for measuring the potency of the tested product.

According to different application, the verification products can be divided into biological standard for the testing of biological products, endocrine drugs, antibiotics and other bioassay and chemical standards including:
1 chemical standards used for calibration of the instrument;
2 chemical reference standards used for calibration of the ultraviolet or infrared spectrum of the drugs;
3 control standards used for the purity test of drugs as well as the impurity control or as the control standards for content determination of the medicine.

In the page 67 of the appendix in the People's Republic of China Pharmacopoeia 1990 1st edition, we can find hundreds kinds of standards including bornyl ester acetate, eugenol and panaxadiol as well as 39 kinds of control medicine for the purify inspection of traditional Chinese medicine, impurity control or the content determination.

International standards
This refers to standard sample, with the potency units of the existing international standard sample potency units as baseline, undergoing further calibration of its potency units on the basis of a wide range of international cooperation. Its potency is expressed in 1U. For a certain product, for the establishment of the first international standard sample, the determination of its potency units should be consulted and decided by the Committee of Experts before the announcement. The international standard is a standard reference substance for worldwide preparation of national standards, so that the international standards can achieve unity.

Reagents and standards
All reagents in the food analysis laboratories should be clearly labeled to indicate the following: 1 name; 2 the date of preparation; 3 Signature from the people in charge; 4 if necessary, we need to add content such as safety and validity and so on.
Most food analysis should use standard sample as reference for qualitative and quantitative determination. The standard sample should be classified according to the following classification methods: 1 international standard; 2 national standards; 3 internal standard; 4 other standards.
Receptacle for reference standards should be clearly affixed to the label, to indicate the following: 1 name; 2 standard document number; 3 Opening times; 4 Validity; 5 Signature.
In addition, the laboratory should keep all the necessary specific files for all the necessary reference standards.
Capacity analysis standard solution should also be strictly managed. It should be clearly posted on all the standard solution containers with labels to indicate: 1 name; 2 concentration; 3 formulation date; 4 No of formulated procedures; 5 storage conditions; 6 validity; 7 Signature from people in charge.

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Structure Chemical Name CAS MF
O-(2,3,4,5,6-PENTAFLUOROBENZYL)FORMALDOXIME O-(2,3,4,5,6-PENTAFLUOROBENZYL)FORMALDOXIME 86356-73-2 C8H4F5NO
M-TOLUALDEHYDE 2,4-DINITROPHENYLHYDRAZONE M-TOLUALDEHYDE 2,4-DINITROPHENYLHYDRAZONE 2880-05-9 C14H12N4O4
3-HYDROXY-P-BUTYROPHENETIDINE 3-HYDROXY-P-BUTYROPHENETIDINE 1083-57-4 C12H17NO3
LINOELAIDIC ACID LINOELAIDIC ACID 506-21-8 C18H32O2
2,3-DINITROTOLUENE 2,3-DINITROTOLUENE 602-01-7 C7H6N2O4
Milbemycin oxime Milbemycin oxime 129496-10-2 2C32H45NO7.2C31H43NO7
DIGOXIGENIN DIGOXIGENIN 1672-46-4 C23H34O5
16-DOXYL-STEARIC ACID 16-DOXYL-STEARIC ACID 53034-38-1 C22H42NO4*
2,6-DIMETHYL-4-NITROSOPHENOL 2,6-DIMETHYL-4-NITROSOPHENOL 14818-35-0 C12H16O2
Zeranol Zeranol 26538-44-3 C18H26O5
SCHRADAN SCHRADAN 152-16-9 C8H24N4O3P2
DIBENZO(A,E)PYRENE DIBENZO(A,E)PYRENE 192-65-4 C24H14
4-Hydroxytolbutamide 4-Hydroxytolbutamide 5719-85-7 C12H18N2O4S
ALPRENOLOL HYDROCHLORIDE ALPRENOLOL HYDROCHLORIDE 13707-88-5 C15H24ClNO2
Flufenacet Flufenacet 142459-58-3 C14H13F4N3O2S
Cythioate Cythioate 115-93-5 C8H12NO5PS2
3,3,5,5-TETRAMETHYL-1-PYRROLINE N-OXIDE 3,3,5,5-TETRAMETHYL-1-PYRROLINE N-OXIDE 10135-38-3 C8H15NO
OXYCODONE HYDROCHLORIDE OXYCODONE HYDROCHLORIDE 124-90-3 C18H22ClNO4
THIOTHIAMINE THIOTHIAMINE 299-35-4 C12H16N4OS2
Methohexital Methohexital 151-83-7 C14H18N2O3
ETHIPROLE ETHIPROLE 181587-01-9 C13H9Cl2F3N4OS
2-Benzhydrylsulphinylacetic acid 2-Benzhydrylsulphinylacetic acid 63547-24-0 C15H14O3S
2-Methylamino-1-(3,4-methylenedioxyphenyl)propan-1-one-hydrochloridepropan-1-one-hydrochloride 2-Methylamino-1-(3,4-methylenedioxyphenyl)propan-1-one-hydrochloridepropan-1-one-hydrochloride 186028-80-8 C11H14ClNO3
ALBENDAZOLE SULFONE ALBENDAZOLE SULFONE 75184-71-3 C12H15N3O4S
METHYL HENEICOSANOATE METHYL HENEICOSANOATE 6064-90-0 C22H44O2
4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] 4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] 27470-51-5 C24H26N2O6
ENTEROKINASE ENTEROKINASE 9014-74-8 NULL
O,P'-DDE O,P'-DDE 3424-82-6 C14H8Cl4
(+)-ISOMENTHOL (+)-ISOMENTHOL 23283-97-8 C10H20O
4-tert-Butyl-2-chlorophenol 4-tert-Butyl-2-chlorophenol 98-28-2 C10H13ClO
PAXILLINE PAXILLINE 57186-25-1 C27H33NO4
DITHIOPYR DITHIOPYR 97886-45-8 C15H16F5NO2S2
GAMMA-LINOLENIC ACID METHYL ESTER GAMMA-LINOLENIC ACID METHYL ESTER 16326-32-2 C19H32O2
CORTISOL 17-VALERATE CORTISOL 17-VALERATE 57524-89-7 C26H38O6
HYDROXYZINE PAMOATE HYDROXYZINE PAMOATE 10246-75-0 C44H43ClN2O8
SUNFLOWER SEED OIL SUNFLOWER SEED OIL 8001-21-6 NULL
1-(2-[4-Chlorophenoxy]acetyl)-4-(3,4-methylenedioxybenzyl)piperazine 1-(2-[4-Chlorophenoxy]acetyl)-4-(3,4-methylenedioxybenzyl)piperazine 34161-24-5 C20H21ClN2O4
(-)-TERPINEN-4-OL (-)-TERPINEN-4-OL 20126-76-5 C10H18O
O-TOLUALDEHYDE 2,4-DINITROPHENYLHYDRAZONE O-TOLUALDEHYDE 2,4-DINITROPHENYLHYDRAZONE 1773-44-0 C14H12N4O4
BENZALDEHYDE 2,4-DINITROPHENYLHYDRAZONE BENZALDEHYDE 2,4-DINITROPHENYLHYDRAZONE 1157-84-2 C13H10N4O4
5-Ethyl-2-(4-isopropyl-4-methyl-5-oxo-1H-imidazolin-2-yl)nicotinic acid 5-Ethyl-2-(4-isopropyl-4-methyl-5-oxo-1H-imidazolin-2-yl)nicotinic acid 81385-77-5 C32H24O3S
CHONDROITIN SULFATE B SODIUM SALT CHONDROITIN SULFATE B SODIUM SALT 54328-33-5 NULL
ETHYL METHYL KETONE 2,4-DINITROPHENYLHYDRAZONE ETHYL METHYL KETONE 2,4-DINITROPHENYLHYDRAZONE 958-60-1 C10H12N4O4
DIHYDROMETHYSTICIN DIHYDROMETHYSTICIN 19902-91-1 C15H16O5
2,4,5,6-TETRACHLORO-M-XYLENE 2,4,5,6-TETRACHLORO-M-XYLENE 877-09-8 C8H6Cl4
DIBENZO[B,DEF]CHRYSENE DIBENZO[B,DEF]CHRYSENE 189-64-0 C24H14
ALPHA,ALPHA'-BIS(4-HYDROXYPHENYL)-1,4-DIISOPROPYLBENZENE ALPHA,ALPHA'-BIS(4-HYDROXYPHENYL)-1,4-DIISOPROPYLBENZENE 2167-51-3 C24H26O2
N-NITROSOPIPERIDINE N-NITROSOPIPERIDINE 100-75-4 C5H10N2O
CIS-11-OCTADECENOIC ACID METHYL ESTER CIS-11-OCTADECENOIC ACID METHYL ESTER 1937-63-9 C19H36O2
Rilmenidine phosphate Rilmenidine phosphate 85409-38-7 C10H19N2O5P
2,4,6-TRICHLOROANISOLE 2,4,6-TRICHLOROANISOLE 87-40-1 C7H5Cl3O
ETHYLHYDROCUPREINE HYDROCHLORIDE ETHYLHYDROCUPREINE HYDROCHLORIDE 3413-58-9 C21H29ClN2O2
DIBENZO(A,I)PYRENE DIBENZO(A,I)PYRENE 191-30-0 C24H14
1(ALPHA) 25-DIHYDROXYVITAMIN D2* 1(ALPHA) 25-DIHYDROXYVITAMIN D2* 60133-18-8 C28H44O3
Demethyl tetrandrine Demethyl tetrandrine 33889-68-8 C37H40N2O6
(-)-alpha-bisabolol (-)-alpha-bisabolol 23089-26-1 C15H26O
4,4'-DDA 4,4'-DDA 83-05-6 C14H10Cl2O2
Calcium levulinate dihydrate Calcium levulinate dihydrate 5743-49-7 C10H18CaO8
HEXOBARBITAL HEXOBARBITAL 56-29-1 C12H16N2O3
DIBUTYL CHLORENDATE DIBUTYL CHLORENDATE 1770-80-5 C17H20Cl6O4
alpha-Ethyl-2-oxo-1-pyrrolidineacetic acid alpha-Ethyl-2-oxo-1-pyrrolidineacetic acid 67118-31-4 C8H13NO3
Potassium trichloroammineplatinate (II) Potassium trichloroammineplatinate (II) 13820-91-2 Cl3H3KNPt
Piretanide Piretanide 55837-27-9 C17H18N2O5S
P-TOLUALDEHYDE 2,4-DINITROPHENYLHYDRAZONE P-TOLUALDEHYDE 2,4-DINITROPHENYLHYDRAZONE 2571-00-8 C14H12N4O4
Flurprimidol Flurprimidol 56425-91-3 C15H15F3N2O2
4-METHOXY-1,3-PHENYLENEDIAMINE SULFATE HYDRATE 4-METHOXY-1,3-PHENYLENEDIAMINE SULFATE HYDRATE 123333-56-2 C7H10N2O.H2O4S
ISOBENZAN ISOBENZAN 297-78-9 C9H4Cl8O
Dihydrokawain Dihydrokawain 587-63-3 C14H16O3
PHENANTHRENE-D10 PHENANTHRENE-D10 1517-22-2 C14D10
Disodium clodronate tetrahydrate Disodium clodronate tetrahydrate 88416-50-6 CH7Cl2NaO7P2
AMCINONIDE AMCINONIDE 51022-69-6 C28H35FO7
2,5-DIMETHYLCYCLOHEXANOL 2,5-DIMETHYLCYCLOHEXANOL 3809-32-3 C8H16O
OXANTEL PAMOATE OXANTEL PAMOATE 68813-55-8 C49H48N4O8
MINAPRINE DIHYDROCHLORIDE MINAPRINE DIHYDROCHLORIDE 25905-77-5 C17H22N4O
2-NITRONAPHTHALENE 2-NITRONAPHTHALENE 581-89-5 C10H7NO2
TRANS-11-OCTADECENOIC ACID TRANS-11-OCTADECENOIC ACID 693-72-1 C18H34O2
Framycetin sulphate Framycetin sulphate 4146-30-9 C23H48N6O17S
Sennoside D Sennoside D 37271-17-3 C42H40O19
PROADIFEN HYDROCHLORIDE PROADIFEN HYDROCHLORIDE 62-68-0 C23H32ClNO2
BUPRENORPHINE HYDROCHLORIDE BUPRENORPHINE HYDROCHLORIDE 53152-21-9 C29H41NO4.ClH
(+/-)-THIOPENTAL (+/-)-THIOPENTAL 76-75-5 C11H18N2O2S
MOLGRASTIM MOLGRASTIM 99283-10-0
TRICHLORONATE TRICHLORONATE 327-98-0 C10H12Cl3O2PS
CHLORDENE CHLORDENE 3734-48-3 C10H6Cl6
Menthyl anthranilate Menthyl anthranilate 134-09-8 C17H25NO2
DIISOPROPYL METHYLPHOSPHONATE DIISOPROPYL METHYLPHOSPHONATE 1445-75-6 C7H17O3P
THIONAZIN THIONAZIN 297-97-2 C8H13N2O3PS
FLUBENDAZOLE FLUBENDAZOLE 37893-02-0 C17H10F6N4S
5-ALPHA-ANDROSTANE 5-ALPHA-ANDROSTANE 438-22-2 C19H32
BETULIN DIACETATE BETULIN DIACETATE 1721-69-3 C34H54O4
N-HEPTATRIACONTANE N-HEPTATRIACONTANE 7194-84-5 C37H76
2-(4-Methoxybenzylamino)pyridine 2-(4-Methoxybenzylamino)pyridine 52818-63-0 C13H14N2O
Dimethenamid Dimethenamid 87674-68-8 C12H18ClNO2S
DibroMoethane-d4 DibroMoethane-d4 22581-63-1 C2Br2D4
Testosterone benzoate Testosterone benzoate 2088-71-3 C26H32O3
OXYPHENCYCLIMINE OXYPHENCYCLIMINE 125-52-0 C20H28N2O3.ClH
FRANGULIN B FRANGULIN B 14101-04-3 C20H18O9
2,3,4-TRICHLOROANISOLE 2,3,4-TRICHLOROANISOLE 54135-80-7 C7H5Cl3O
2-Aminoperimidine Hydrobromide 2-Aminoperimidine Hydrobromide 40835-96-9 C11H10BrN3
FRANGULIN A FRANGULIN A 521-62-0 C21H20O9
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