| Company Name: |
Nanjing Tengyi Biotechnology Co., Ltd
|
| Tel: |
025-58851786 17714337195 |
| Email: |
sales@tybiochem.com |
| Products Intro: |
Cas:318-98-9
ProductName:Propranolol HCl
Purity: 98% | Package: 1g;5g;10g | CustNote: 500gg
|
| Company Name: |
Hunan HuaTeng Pharmaceutical Co., Ltd.,
|
| Tel: |
400-8592883 15367835770 |
| Email: |
viola@huatengsci.com |
| Products Intro: |
Cas:318-98-9
ProductName:Propranolol HCl
Purity: 咨询热线400-859-2883 | Package: 0.98
|
- Propranolol
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- $0.00 / 1kg
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2024-05-27
- CAS:525-66-6
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20tons
- Propranolol hydrochloride
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- $15.00 / 1KG
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2021-07-13
- CAS:318-98-9
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- R(+)-PROPRANOLOL HCL
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- $7.00 / 1KG
-
2020-01-10
- CAS:5051-22-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100KG
|
| | Propranolol Hcl Basic information |
| | Propranolol Hcl Chemical Properties |
| | Propranolol Hcl Usage And Synthesis |
| Description | Propranolol hydrochloride is a off-white to light-yellow cyrstalline solid, easily soluble in ethanol and water.
| | Uses |
Propranolol Hcl is a beta blocker used to treat high blood pressure, irregular heartbeats, shaking (tremors), and other conditions. It is used after a heart attack to improve the chance of survival. It is also used to prevent migraine headaches and chest pain (angina).
| | Brand name | Inderal,Avlocardyl, Deralin, Dociton, Inderalici, InnoPran XL, Indoblok,Sumial, Anaprilin, and Bedranol SR (Sandoz),Ciplar,Ciplar LA
| | Mechanism of action |
Propranolol is classified as a competitive non-cardioselective sympatholytic beta blocker that crosses the blood–brain barrier. It is lipid soluble and also has sodium channel blocking effects. Propranolol is a non-selective β-adrenergic receptor antagonist, or beta blocker.Propranolol is able to cross the blood–brain barrier and exert effects in the central nervous system in addition to its peripheral activity.
| | Pharmacokinetics |
Propranolol Hcl is rapidly and completely absorbed, with peak plasma levels achieved about 1–3 hours after ingestion. More than 90% of the drug is found bound to plasma protein in the blood.Coadministration with food appears to enhance bioavailability.Despite complete absorption, propranolol has a variable bioavailability due to extensive first-pass metabolism. Hepatic impairment therefore increases its bioavailability. The main metabolite 4-hydroxypropranolol, with a longer half-life (5.2–7.5 hours) than the parent compound (3–4 hours), is also pharmacologically active. Most of the metabolites are excreted in the urine.
| | Side effects | Common side effects include nausea, abdominal pain, and constipation.It may worsen the symptoms of asthma.Propranolol may cause harmful effects for the baby if taken during pregnancy.
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| | Propranolol Hcl Preparation Products And Raw materials |
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