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Mangostin

Mangostin Suppliers list
Company Name: Chengdu Biopurify Phytochemicals Ltd.
Tel: +8618080483897
Email: sales@biopurify.com
Products Intro: Product Name:Alpha-Mangostin
CAS:6147-11-1
Purity:0.98 Package:10mg;20mg;50mg;100mg;500mg Remarks:Can Be Customized in Bulk
Company Name: Hebei Mojin Biotechnology Co., Ltd
Tel: +8613288715578
Email: sales@hbmojin.com
Products Intro: Product Name:Mangostin
CAS:6147-11-1
Purity:99% Package:25KG
Company Name: Shanghai Affida new material science and technology center
Tel: +undefined15081010295
Email: 2691956269@qq.com
Products Intro: Product Name:Mangostin
CAS:6147-11-1
Purity:99 Package:1KG;0.00;USD|5KG;0.00;USD|25KG;0.00;USD Remarks:5KG;1KG;25KG
Company Name: BINBO BIOLOGICAL CO.,LTD
Tel: +8618629063126
Email: info@binbobiological.com
Products Intro: Product Name:Mangostin
CAS:6147-11-1
Purity:>98% Package:1kg
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512
Email: info@tianfuchem.com
Products Intro: Product Name:TIANFU-CHEM Mangostin
CAS:6147-11-1
Purity:99% Package:25KG;5KG;1KG

Mangostin manufacturers

  • Mangostin
  • Mangostin pictures
  • $0.00 / 1KG
  • 2024-04-15
  • CAS:6147-11-1
  • Min. Order: 1KG
  • Purity: 99
  • Supply Ability: 50000KG/month
  • Mangostin
  • Mangostin pictures
  • $0.00 / 1kg
  • 2024-04-11
  • CAS:6147-11-1
  • Min. Order: 1kg
  • Purity: >98%
  • Supply Ability: 1000 kg
Mangostin Basic information
Product Name:Mangostin
Synonyms:α-Mangostin (a-Mangostin、ALPHA-Mangostin);α-Mangostin, froM Garcinia Mangostana;1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methyl-2-butenyl)-9H-xanthen-9-on;Alpha-Mangostin α-Mangostin;1,3,6-Trihydroxy-7-methoxy-2,8-bis(3-methyl-2-butenyl)-9H-xanthen-9-one;1,3,6-TRIHYDROXY-7-METHOXY-2,8-DI(3-METHYL-2-BUTENYL)XANTHONE;Mangosteen;mangostin
CAS:6147-11-1
MF:C24H26O6
MW:410.46
EINECS:683-120-1
Product Categories:reagent;standard substance;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Xanthones;Intermediates & Fine Chemicals;Pharmaceuticals;chemical reagent;pharmaceutical intermediate;phytochemical
Mol File:6147-11-1.mol
Mangostin Structure
Mangostin Chemical Properties
Melting point 180-182°C
Boiling point 640.1±55.0 °C(Predicted)
density 1.265±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility methanol: soluble1mg/mL, clear, very light yellow
form powder
pka7.22±0.20(Predicted)
color faint yellow to yellow
λmax346nm(MeOH)(lit.)
Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIInChI=1S/C24H26O6/c1-12(2)6-8-14-16(25)10-19-21(22(14)27)23(28)20-15(9-7-13(3)4)24(29-5)17(26)11-18(20)30-19/h6-7,10-11,25-27H,8-9H2,1-5H3
InChIKeyGNRIZKKCNOBBMO-UHFFFAOYSA-N
SMILESC1(=O)C2=C(C=C(O)C(OC)=C2C/C=C(/C)\C)OC2=C1C(O)=C(C/C=C(/C)\C)C(O)=C2
CAS DataBase Reference6147-11-1(CAS DataBase Reference)
Safety Information
Hazard Codes T
Risk Statements 25
Safety Statements 45
RIDADR UN 2811 6.1 / PGIII
WGK Germany 1
RTECS ZD6122420
HS Code 29329990
Hazardous Substances Data6147-11-1(Hazardous Substances Data)
MSDS Information
Mangostin Usage And Synthesis
Descriptionα-Mangostin (6147-11-1) is a xanthone natural product that has historically been used in traditional folk medicine.1 It is a potent agonist of human STING (Stimulator of Interferon Genes) and also weakly activates mouse STING.2 Induces IFN-β production and repolarizes human monocyte-derived M2 macrophages to M1. Improves insulin secretion and protects INS-1 cells from streptozotocin-induced damage.3 Suppresses the metastasis of human renal carcinoma cells.4 Synergizes with kinase inhibitors in suppression of proliferation of SK-MEL-2 malignant melanoma cells.5
Chemical PropertiesYellow Crystalline Solid
Usesα-Mangostin has been used:
  • to study its protective effect against oxidative stress mediated-retinal cell death
  • to study its role as an antigenotoxic agent in DNA protection against oxidative damage
  • to understand its anti-bacterial activity against Staphylococcus epidermidis?RP62A
Usesantifungal, antilarval
UsesIt was isolated from Garcinia mangostana Linn (Guttiferae). It is an anti-inflammatory agent
DefinitionChEBI: Alpha-mangostin is a member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1, 3 and 6, a methoxy group at position 7, an oxo group at position 9 and prenyl groups at positions 2 and 8. Isolated from the stems of Cratoxylum cochinchinense, it exhibits antioxidant, antimicrobial and antitumour activities. It has a role as an antineoplastic agent, an antimicrobial agent, an antioxidant and a plant metabolite. It is a member of xanthones, a member of phenols and an aromatic ether.
General DescriptionThis substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Biochem/physiol ActionsXanthone derivative isolated from mangosteen (Garcinia mangostana). Antioxidant and anti-inflammatory. α-mangostin has been shown to induce apoptosis via the mitochondrial pathway, reduce cell proliferation and inhibit tumorigenesis.
storageStore at -20°C
References1) Mohan et al. (2018), An anti-inflammatory molecular mechanism of action of α-mangostin, the major xanthone from the pericarp of Garcinia mangostana: an in silico, in vitro and in vivo approach; Food Funct., 9 3860 2) Zhang et al. (2018), Identification of α-Mangostin as an Agonist of Human STING; Chem. Med. Chem.,?13 2057 3) Lee et al. (2018), Alpha-Mangostin Improves Insulin Secretion and Protects INS-1 Cells from Streptozotocin-induced Damage; J. Mol. Sci., 19 E1484 4) Chen et al. (2017), Alpha-Mangostin Suppresses the Metastasis of Human renal Carcinoma Cells by Targeting MEK/ERK Expression and MMP-9 Transcription Activity; Cell Physiol. Biochem., 44 1460 5) Xia and Sun (2018), Synergistic inhibition of cell proliferation by combined targeting with kinase inhibitors and dietary xanthone is a promising strategy for melanoma treatment; Clin. Exp. Dermatol., 43 149
Mangostin Preparation Products And Raw materials
Preparation ProductsBeta-mangostin
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