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Orciprenaline

Orciprenaline Suppliers list
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Products Intro: Product Name:Orciprenaline
CAS:586-06-1
Purity:97%-99% Package:1KG;8.8USD
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Products Intro: Product Name:Orciprenaline
CAS:586-06-1
Purity:0.98 Package:1kg,2kg,5kg,10kg,25kg
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Products Intro: Product Name:Metaproterenol;Orciprenaline
CAS:586-06-1
Purity:98.00% Package:100 mg;500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
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Products Intro: Product Name:orciprenaline
CAS:586-06-1
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Products Intro: Product Name:Orciprenaline
CAS:586-06-1
Purity:99.9% Package:1g;1.1USD Remarks:FDA GMP CEP Approved Manufacturer

Orciprenaline manufacturers

  • Orciprenaline
  • Orciprenaline pictures
  • $8.80 / 1KG
  • 2019-07-06
  • CAS:586-06-1
  • Min. Order: 1KG
  • Purity: 97%-99%
  • Supply Ability: 100kg
Orciprenaline Basic information
Product Name:Orciprenaline
Synonyms:5-[1-hydroxy-2-(1-methylethylamino)ethyl]benzene-1,3-diol;5-(1-hydroxy-2-propan-2-ylamino-ethyl)benzene-1,3-diol;orciprenaline;1-(3,5-dihydroxyphenyl)-2-isopropylaminoethanol;1,3-Benzenediol, 5-1-hydroxy-2-(1-methylethyl)aminoethyl-;1,3-Benzenediol, 5-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]- (9CI);3,5-Dihydroxy-a-[(isopropylamino)methyl]benzyl alcohol;Benzyl alcohol, 3,5-dihydroxy-a-[(isopropylamino)methyl]- (6CI, 8CI)
CAS:586-06-1
MF:C11H17NO3
MW:211.26
EINECS:2095691
Product Categories:Orciprenaline
Mol File:586-06-1.mol
Orciprenaline Structure
Orciprenaline Chemical Properties
Melting point 100°
Boiling point 350.94°C (rough estimate)
density 1.1240 (rough estimate)
refractive index 1.5718 (estimate)
pka9.11±0.10(Predicted)
CAS DataBase Reference586-06-1(CAS DataBase Reference)
Safety Information
MSDS Information
Orciprenaline Usage And Synthesis
OriginatorAlupent, Boehringer Ingelheim ,W. Germany ,1961
UsesBronchodilator.
DefinitionChEBI: Metaproterenol is a member of phenylethanolamines.
Manufacturing ProcessIn an initial operation, 3,5-diacetoxyacetophenone was reacted first with bromine and then with isopropylamine to give 1-(3,5-dihydroxyphenyl)-2- isopropylaminoethanone.
59 g of 1-(3,5-dihydroxy-phenyl)-2-isopropylaminoethanone (free base) were dissolved in 590 cc of methanol, and the solution was hydrogenated in the presence of about 80 g Raney nickel at room temperature and under a pressure of 5 atm. Hydrogen absorption was terminated after a few minutes. The catalyst was separated by vacuum filtration, and the filtrate, an ethanolic solution of 1-(3,5-dihydroxyphenyl)-1-hydroxy-2-isopropylaminoethane, was admixed with the calculated amount of an alcoholic 20% sulfuric acid solution. A crystalline precipitate formed which was filtered off and washed with alcohol. For purification, the product was dissolved in water and the solution was filtered through iron-free charcoal.
Thereafter, the filtrate was evaporated to dryness in vacuo and the residue was taken up in alcohol. The crystalline precipitate which separated out after some standing was separated by vacuum filtration and washed with alcohol. After recrystallization from 90% alcohol, 61 g (83.2% of theory) of 1-(3,5- dihydroxyphenyl)-1-hydroxy-2-isopropylamino-ethane sulfate, MP 202° to 203°C, was obtained.
Therapeutic FunctionBronchodilator
Clinical UseMetaproterenol was the first β- sympathomimetic drug with metabolic stability to achieve wide clinical use.
Orciprenaline Preparation Products And Raw materials
Raw materialsAcetone-->Isopropylamine-->Hydrogen
Tag:Orciprenaline(586-06-1) Related Product Information
Acetaminophen Ethyl maltol 5-(1-Hydroxy-2-tert-butylamino-ethyl)benzene-1,3-diol 3-Diethylaminophenol Ethylparaben Ethyl cyanoacetate Ethyl acetate Benzene CHLOROPHOSPHONAZO III ISOXADIFEN-ETHYL N,N-Diisopropylethylamine Ethyl acrylate 1-Hydroxyethylidene-1,1-diphosphonic acid Ethanol ibuterol Bambuterol hydrochloride TERBUTALINE SULFATE dl-Orciprenaline sulfate,ORCIPRENALINE SULPHATE(METAPROTERENOL),ORCIPRENALINE SULFATE