ChemicalBook > Product Catalog >Organic Chemistry >Amides >Naphthenic amines derivatives >N-Methylaniline

N-Methylaniline

N-Methylaniline Suppliers list
Company Name: Jiangsu King Road New Materials Co., Ltd
Tel: +8613584535752
Email: info@jskingroad.com
Products Intro: Product Name:N-methylaniline
CAS:100-61-8
Purity:99% Package:200KG;USD|1000KG;USD|16000KG;USD
Company Name: SIMAGCHEM CORP
Tel: +86-13806087780
Email: sale@simagchem.com
Products Intro: Product Name:monomethyl aniline
CAS:100-61-8
Purity:0.99 Package:1kg,5kg,25kgs,200kgs;bulk
Company Name: Tianjin Zhongxin Chemtech Co., Ltd.
Tel: +86-022-66880623 +8618622897568
Email: sales@tjzxchem.com
Products Intro: Product Name:N-Methylaniline
CAS:100-61-8
Purity:99%min Package:200kg drum Remarks:Also could supply the assay 95% and 93% or as customers demand
Company Name: Xiamen AmoyChem Co., Ltd
Tel: +86-86-5926051114 +8618959220845
Email: sales@amoychem.com
Products Intro: Product Name:N-Methylaniline
CAS:100-61-8
Company Name: Yancheng Green Chemicals Co.,Ltd
Tel: +undefined-86-25-86655873
Email: info@royal-chem.com
Products Intro: Product Name:N-Methylaniline
CAS:100-61-8
Purity:99% Package:1000kg;2430USD

N-Methylaniline manufacturers

  • N-Methylaniline
  • N-Methylaniline pictures
  • $2430.00 / 1000kg
  • 2024-12-04
  • CAS:100-61-8
  • Min. Order: 5000kg
  • Purity: 99%
  • Supply Ability: 200 mt
  • N-Methylaniline
  • N-Methylaniline  pictures
  • $2430.00 / 1000kg
  • 2024-12-04
  • CAS:100-61-8
  • Min. Order: 5000kg
  • Purity: 99%
  • Supply Ability: 200 mt
  • N-Methylaniline
  • N-Methylaniline pictures
  • $1.00 / 200ASSAYS
  • 2024-12-04
  • CAS:100-61-8
  • Min. Order: 1ASSAYS
  • Purity: 99
  • Supply Ability: 200MT

Related articles

  • What is N-methylaniline?
  • N-methylaniline appears as a colorless to brown viscous liquid. Insoluble in water and denser than water. Contact may irritate....
  • Aug 27,2021
  • The uses of N-methylaniline
  • N-methylaniline appears as a colorless to brown viscous liquid. Insoluble in water and denser than water. Contact may irritate....
  • Sep 23,2019
N-Methylaniline Basic information
Product Name:N-Methylaniline
Synonyms:N-METHYLANILINE;N-METHYLAMINOBENZENE;Benzenamine, N-methyl-;Benzenenamine, N-methyl-;methylaniline(non-specificname);methylaniline-n;Methylphenylamine;n’-BIcthylanilin
CAS:100-61-8
MF:C7H9N
MW:107.15
EINECS:202-870-9
Product Categories:Amines;Building Blocks;C7;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Fine Intermediate;Anilines, Aromatic Amines and Nitro Compounds;Organics;Intermediates of Dyes and Pigments;100-61-8
Mol File:100-61-8.mol
N-Methylaniline Structure
N-Methylaniline Chemical Properties
Melting point -57 °C (lit.)
Boiling point 196 °C (lit.)
density 0.989 g/mL at 25 °C (lit.)
vapor pressure 0.5 hPa (20 °C)
refractive index n20/D 1.571(lit.)
Fp 174 °F
storage temp. Store below +30°C.
solubility water: slightly soluble30g/L
pka4.84(at 25℃)
form Liquid
color Clear yellow to brown
PH7.6 (1g/l, H2O, 20℃)
OdorModerate aniline-type.
Water Solubility 30 g/L
Sensitive Air Sensitive
Merck 14,6019
BRN 741982
Henry's Law Constant(x 10-5 atm?m3/mol): 1.19 at 25 °C (approximate - calculated from water solubility and vapor pressure)
Exposure limitsNIOSH REL: TWA 0.5 ppm (2 mg/m3), IDLH 100 ppm; OSHA PEL: TWA 2 ppm (9 mg/m3); ACGIH TLV: TWA 0.5 ppm (adopted).
Dielectric constant6.0(22℃)
Stability:Incompatible with strong oxidizing agents. Discolours upon exposure to air.
InChIKeyAFBPFSWMIHJQDM-UHFFFAOYSA-N
LogP1.66 at 20℃
CAS DataBase Reference100-61-8(CAS DataBase Reference)
NIST Chemistry ReferenceAniline, N-methyl-(100-61-8)
EPA Substance Registry SystemN-Methylaniline (100-61-8)
Safety Information
Hazard Codes T,N
Risk Statements 23/24/25-33-50/53
Safety Statements 28-36/37-45-60-61-28A
RIDADR UN 2294 6.1/PG 3
OEBB
OELTWA: 0.5 ppm (2 mg/m3) [skin]
WGK Germany 3
RTECS BY4550000
8
Autoignition Temperature500 °C
TSCA Yes
HazardClass 6.1
PackingGroup III
HS Code 29214200
Hazardous Substances Data100-61-8(Hazardous Substances Data)
ToxicityLD in rabbits (g/kg): 0.28 orally; in rabbits, cats (mg/kg): 24, 24 i.v. (Treon)
IDLA100 ppm
MSDS Information
ProviderLanguage
Monomethylaniline English
SigmaAldrich English
ACROS English
ALFA English
N-Methylaniline Usage And Synthesis
DescriptionN-Methylaniline is a yellow to light brown oily liquid with a weak, ammonia-like odor. Turns reddishbrown if left standing. The odor threshold is 1.7 ppm. Molecular weight= 107.17; Specific gravity (H2O:1)= 0.99;Boiling point=195.6℃; Freezing/Melting point=57.2℃; Vapor pressure= 0.3 mmHg at 20℃; Flash point=79.4℃. Hazard Identification (based on NFPA-704 M Rating System): Health 2, Flammability 2, Reactivity 0. Practically insoluble in water.
Chemical PropertiesN-Methylaniline is a yellow to light brown oily liquid with a weak, ammonia-like odor. soluble in ethanol, ether, chloroform, slightly soluble in water. Turns reddishbrown if left standing.
Physical propertiesColorless to yellow to pale brown liquid with a faint, ammonia-like odor. Odor threshold concentration is 1.7 ppm (quoted, Amoore and Hautala, 1983).
UsesN-Methylaniline is used as a solvent and in organic synthesis. It is used in the production of cationic brilliant red FG, cationic pink B, reactive yellow brown KGR, etc. in the dye industry. N-methylaniline is an intermediate in the synthesis of the insecticide buprofezin and the herbicide mefenacet.
UsesN-methylaniline was used as raw material, and metal-organic skeleton material CAU-10pydc was used as catalyst to catalyze the reaction of CO2 with n-methylaniline to produce N-methyl-N-phenylformamide in mild conditions and green solvent acetonitrile[1]. Poly (N-methylaniline) (PNMA) was prepared by the electrooxidation of N-methylaniline in acidic aqueous solution. PNMA prepared in acidic aqueous solution with different organic solvents and anions had different conductivity. Such as the experimental group added acetonitrile, N, N-dimethylformamide and dimethylsulfoxide, and the experimental group which adding dimethylsulfoxide had the strongest conductivity[2].
References:
[1] Zhiqiang Wang, Chenghua Deng, Xiao Liu, Wenmin Wang, Highly efficient conversion of CO2 into N-formamides catalyzed by a noble-metal-free aluminum-based MOF under mild conditions, 2023, 52, 11163-11167.
[2] Jun YANO , Hiroko YOSHIKAWA , Tomomi MUKAI , Sumio YAMASAKI , Akira KITANI, Effect of Anions and Added Organic Solvents of Polymerizing Solutions on the Conductivity of Poly (N-methylaniline), 2006, 74, 42-48.
PreparationN-methylaniline was synthesized by the reaction of aniline with dimethyl sulfate. Dimethyl sulfate was added dropwise to the mixed solution of aniline and water below 10°C, stirred for 1 h, and then added dropwise with 30% sodium hydroxide solution. The upper layer is the organic phase, and the lower layer is extracted with benzene. After the benzene is recovered from the extract, the obtained oil Chemicalbook-like substance is combined with the organic phase to obtain a mixture of aniline, N-methylaniline and N,N-dimethylaniline. The mixture was treated with sulfuric acid, and the aniline formed sulfate crystals which were filtered off. N,N-dimethylaniline can be converted to N-methylaniline by the following reaction.
ApplicationN-Methylaniline (NMA) was used in the preparation of self-assembled poly(N-methylaniline)-lignosulfonate (PNMA-LS) composite spheres with reactive silver-ion adsorbability. NMA was also used in electrodeposition of poly(N-methylaniline) (PNMA) coatings on a steel disc electrode using potentiodynamic, potentiostatic and galvanostatic techniques.
DefinitionChEBI: N-methylaniline is a methylaniline that is aniline carrying a methyl substituent at the nitrogen atom. It is a phenylalkylamine, a secondary amine and a methylaniline. It derives from an aniline.
Synthesis Reference(s)Chemical and Pharmaceutical Bulletin, 14, p. 1007, 1966 DOI: 10.1248/cpb.14.1007
Journal of the American Chemical Society, 107, p. 493, 1985 DOI: 10.1021/ja00288a037
Synthetic Communications, 13, p. 601, 1983 DOI: 10.1080/00397918308059535
General DescriptionChemical oxidation of N-methylaniline with dichromate (oxidant) has been studied by Raman spectroscopy.
HazardToxic by ingestion, inhalation, and skin absorption. Methemoglobinemia and central nervous system impairment.
Health HazardRecommended Personal Protective Equipment: Approved respirator; rubber gloves; splash proof goggles; Symptoms Following Exposure: Inhalation causes dizziness and headache. Ingestion causes bluish discoloration (cyanosis) of lips, ear lobes, and fingernail beds. Liquid irritates eyes. Absorption through skin produces same symptoms as for ingestion; General Treatment for Exposure: INHALATION: remove victim to fresh air and call a physician at once; administer oxygen until physician arrives. INGESTION: give large amount of water; get medical attention at once. EYES or SKIN: flush with plenty of water for at least 15 min.; if cyanosis is present, shower with soap and warm water, with special attention to scalp and finger nails; remove any contaminated clothing; Toxicity by Inhalation (Threshold Limit Value): Data not available; Short-Term Inhalation Limits: Data not available; Toxicity by Ingestion: Data not available; Late Toxicity: Data not available; Vapor (Gas) Irritant Characteristics: Data not available; Liquid or Solid Irritant Characteristics: Data not available; Odor Threshold: Data not available.
Chemical ReactivityReactivity with Water No reaction; Reactivity with Common Materials: May attack some forms of plastic; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
Safety ProfilePoison by ingestion and intravenous routes. Moderately toxic by subcutaneous route. When heated to decomposition it emits toxic fumes of NOx.
Potential ExposureThe material is used as an intermediate in organic synthesis, as a solvent and as an acid acceptor
First aidIf this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. Medical observation is recommended for 2448 h after breathing overexposure, as pulmonary edema may be delayed. As first aid for pulmonary edema, a doctor or authorized paramedic may consider administering a corticosteroid spray. Note to physician: Treat for methemoglobinemia. Spectrophotometry may be required for precise determination of levels of methemoglobin in urine.
CarcinogenicityN-methyl aniline (1.95 g/kg of food) given together with sodium nitrite (1.0 g/l of drinking water) to Swiss mice resulted in a 17% incidence of lung adenomas and a 14% incidence of malignant lymphomas; there were no carcinogenic effects in animals treated with Nmethyl aniline alone, suggesting that in vivo nitrosation is necessary for forming carcinogenic nitrosamines.
In bacterial mutagenicity assays N-methyl aniline was negative with or without metabolic activation.
Environmental fateSoil. Reacts slowly with humic acids or humates forming quinoidal structures (Parris, 1980).
storageColor Code—Blue: Health Hazard/Poison: Store in a secure poison location. Prior to working with this chemical you should be trained on its proper handling and storage. Methylaniline must be stored to avoid contact with strong acids (such as hydrochloric, sulfuric, and nitric), since violent reactions occur. Store in tightly closed containers in a cool, well-ventilated area away from heat. Sources of ignition, such as smoking and open flames, are prohibited where methylaniline is used, handled, or stored in a manner that could create a potential fire or explosion hazard.
ShippingUN2294 N-Methylaniline, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
Purification MethodsDry it with KOH pellets and fractionally distil it under vacuum. Acetylate, and the acetyl derivative is recrystallised to constant melting point (m 101-102o), then hydrolysed with aqueous HCl and distilled from zinc dust under reduced pressure. [Hammond & Parks J Am Chem Soc 77 340 1955, Beilstein 12 IV 241.]
IncompatibilitiesReacts violently with strong acids, acid chlorides, acid anhydrides, strong oxidizers. Attacks some plasti℃.
Waste DisposalControlled incineration whereby oxides of nitrogen are removed from the effluent gas by scrubber, catalytic or thermal device.
Tag:N-Methylaniline(100-61-8) Related Product Information
N,N-Dimethyl-1,4-phenylenediamine N-Methyl-4-nitroaniline 3,3',5,5'-Tetramethylbenzidine dihydrochloride o-Toluidine p-Toluidine N,N-Dimethylaniline N-Methyl-2-pyrrolidone N-(2-Hydroxyethyl)-N-methylaniline N-(2-HYDROXYETHYL)-N-METHYL-4-TOLUIDINE 4-Nitro-N-methylphthalimide N-Methylbenzamide N-Methylformanilide 3-CHLORODIPHENYLAMINE 4'-CHLOROACETANILIDE 4'-Bromoacetanilide 4-Bromo-N,N-dimethylaniline 2-Chloro-N-(2,6-dimethylphenyl)acetamide Diphenylcarbamyl chloride