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| | 1'-Hydroxybufuralol Basic information |
| Product Name: | 1'-Hydroxybufuralol | | Synonyms: | Ro 03-7410;2-(tert-Butylamino)-1-[7-(1-hydroxyethyl)-1-benzofuran-2-yl]ethanol;1’-Hydroxy Bufuralol (Mixture of Diastereomers);1'-Hydroxybufuralol;α2-[[(1,1-DiMethylethyl)aMino]Methyl]-α7-Methyl-;2-(tert-
Butylamino)-1-(7-(1-
hydroxyethyl)benzofuran-2-
yl)ethanol maleate;Bufuralol Impurity 3(Mixture of Diastereomers);Bufuralol Impurity 3-d9(Mixture of Diastereomers) | | CAS: | 57704-16-2 | | MF: | C16H23NO3 | | MW: | 277.36 | | EINECS: | | | Product Categories: | Aromatics;Heterocycles;Metabolites & Impurities | | Mol File: | 57704-16-2.mol |  |
| | 1'-Hydroxybufuralol Chemical Properties |
| Melting point | 41-49°C | | Boiling point | 433.0±40.0 °C(Predicted) | | density | 1.139±0.06 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated) | | form | Solid | | pka | 13.58±0.20(Predicted) | | color | Off-White to Beige | | Stability: | Hygroscopic |
| | 1'-Hydroxybufuralol Usage And Synthesis |
| Description | 1’-hydroxy Bufuralol is a metabolite of bufuralol . Bufuralol is metabolized by the cytochrome P450 isoforms 2D1 and 2D2 (CYP2D1/2); therefore, quantification of the bufuralol metabolite, 1’-hydroxy bufuralol, can be used to determine CYP2D1/2 enzyme activity in humans and rats. | | Chemical Properties | White to Off-White Solid | | Uses | A metabolite of Bufuralol, a β-Adrenergic blocker with peripheral vasodilating activity. |
| | 1'-Hydroxybufuralol Preparation Products And Raw materials |
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