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2-Chlorotoluene Suppliers list
Company Name: Xiamen AmoyChem Co., Ltd
Tel: +86-592-6051114 +8618959220845
Products Intro: Product Name:O-Clorotoluene
Purity:99.00% Package:200kg per barrel Remarks:Pharma Intermediate;Fine Intermediate
Company Name: Ningxia Jinhua Chemical Co.,Ltd
Tel: 025-52279164
Products Intro: Product Name:2-Chlorotoluene
Purity:99 Package:25Kg/Drum;USD
Company Name: Shaanxi Didu New Materials Co. Ltd
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Purity:0.99 Package:25KG,200L
Company Name: Wuhan Boyuan Import & Export Co., LTD
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Products Intro: Product Name:2-Chlorotoluene
Purity:99.96% Package:1kg;6USD
Company Name: Hebei Yanxi Chemical Co., Ltd.
Tel: +8617531190177
Products Intro: Product Name:2-Chlorotoluene
Purity:0.99 Package:1kg;20USD|100kg;10USD|1000kg;1USD Remarks:Factory direct sales

2-Chlorotoluene manufacturers

  • 2-Chlorotoluene
  • 2-Chlorotoluene pictures
  • $0.00 / 200Kg/Drum
  • 2023-12-11
  • CAS:95-49-8
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 5000MT/year
  • 2-Chlorotoluene
  • 2-Chlorotoluene pictures
  • $20.00 / 1kg
  • 2023-11-11
  • CAS:95-49-8
  • Min. Order: 1kg
  • Purity: 0.99
  • Supply Ability: 20 tons
  • 2-Chlorotoluene
  • 2-Chlorotoluene pictures
  • $0.00 / 1KG
  • 2023-09-06
  • CAS:95-49-8
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 500000kg

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2-Chlorotoluene Basic information
Product Name:2-Chlorotoluene
Synonyms:1-chloro-2-methyl-benzen;2-Chloro-1-methylbenzene,o-tolylchloride;2-Chlortoluol;1-Methyl-2-chlorobenzene;toluene,2-chloro-;Toluene,o-chloro-;2-CHLOROTOLUENE, 1000MG, NEAT;2-CHLOROTOLUENE PESTANAL
Product Categories:hormones;Pesticides intermediate;Alphabetic;C;CH;Aryl;C7;Halogenated Hydrocarbons;Alpha Sort;CAlphabetic;Volatiles/ Semivolatiles;Pesticides&Metabolites;Analytical Chemistry;Standard Solution of Volatile Organic Compounds for Water & Soil Analysis;Standard Solutions (VOC);Organics
Mol File:95-49-8.mol
2-Chlorotoluene Structure
2-Chlorotoluene Chemical Properties
Melting point -36 °C (lit.)
Boiling point 157-159 °C (lit.)
density 1.083 g/mL at 25 °C (lit.)
vapor density 4.38 (vs air)
vapor pressure 10 mm Hg ( 43 °C)
refractive index n20/D 1.525(lit.)
Fp 117 °F
storage temp. 0-6°C
solubility H2O: slightly soluble0.047g/L at 20°C
form Liquid
color Clear
explosive limit1.0-12.6%(V)
Water Solubility slightly soluble
Merck 14,2171
BRN 1904175
Dielectric constant4.4500000000000002
Exposure limitsACGIH: TWA 50 ppm
NIOSH: TWA 50 ppm(250 mg/m3); STEL 75 ppm(375 mg/m3)
LogP3.42 at 25℃
CAS DataBase Reference95-49-8(CAS DataBase Reference)
NIST Chemistry ReferenceBenzene, 1-chloro-2-methyl-(95-49-8)
EPA Substance Registry Systemo-Chlorotoluene (95-49-8)
Safety Information
Hazard Codes Xn,N,F,Xi,T
Risk Statements 20-51/53-39/23/24/25-23/24/25-11
Safety Statements 24/25-61-45-36/37-16-7
RIDADR UN 2238 3/PG 3
WGK Germany 2
RTECS XS9000000
Autoignition Temperature600°C
Hazard Note Irritant/Flammable
HazardClass 3
PackingGroup III
HS Code 29036990
Hazardous Substances Data95-49-8(Hazardous Substances Data)
MSDS Information
1-Chloro-2-methylbenzene English
SigmaAldrich English
ACROS English
ALFA English
2-Chlorotoluene Usage And Synthesis
Description2-Chlorotoluene can be mineralized completely by Rhodococcus, strain OCT 10 DSM 45596(T). It is used in the preparation of 3-chloro-4-methylcatechol and 4-chloro-3-methylcatechol. The oxidation of 2-chlorotoluene is very well catalyzed by the enzymes: toluene dioxygenase of P. putida F1 and chlorobenzene dioxygenase from Burkholderia, strain PS12.
Chemical Propertieso-Chlorotoluene is a flammable, colorless liquid with an aromatic odor.
UsesSolvent; synthesis of dyes, pharmaceuticals, and synthetic rubber compounds
UsesSolvent and intermediate for organic chemicals and dyes.
2-Chlorotoluene is used for permanganate oxidation to give o-chlorobenzoic acid. It is used in the preparation of 3-chloro-4-methylcatechol and 4-chloro-3-methylcatechol.
2-Chlorotoluene can be used as a precursor to synthesize aryl coupling products via palladium-catalyzed Negishi cross-coupling. It can also be used in the Buchwald-Hartwig amination to synthesize arylamines.
PreparationThe solution of cuprous chloride is cooled in an ice bath 0-5° C temperature. In this cold solution, the 2-methylbenzenediazonium is poured with constant shaking and allowing the mixture to come to room temperature. After about 10 minutes, the mixture gradually warmed with a good shaking.As the temperature rises the brown addition product begins to decompose with the evolution of nitrogen and with the formation of an oily layer of 2-chlorotoluene. When the decomposition reaction is at an end, the mixture is steam distilled, continuing the process only as long as oily droplets are present in the distillate, for the product is not appreciably soluble in water. The layer of 2-chlorotoluene is carefully separated and washed twice with an equal volume of concentrated sulfuric acid, which removes both the 2-cresol and the azo compound. Then 2-chlorotoluene is washed with water in order to remove the inorganic acid. Finally, 2-chlorotoluene is dried over calcium chloride, distilled, using an air condenser and collecting the product boiling at 153-158° C. Pure 2-chlorotoluene boils at 157° C. The yield is 25-30 g.
synthesis of 2-chlorotoluene
Experiments in Organic Chemistry, L. F. Fieser, 216, 1941
Highly Selective Oxidative Monochlorination To Synthesize Organic Intermediates: 2-Chlorotoluene, 2-Chloroaniline, 2-Chlorophenol, and 2-Chloro-4-methylphenol
Synthesis Reference(s)Journal of the American Chemical Society, 101, p. 768, 1979 DOI: 10.1021/ja00497a063
Organic Syntheses, Coll. Vol. 1, p. 170, 1941
General DescriptionColorless liquid with an aromatic odor. Denser than water and poorly soluble in water. Hence sinks in water .
Air & Water ReactionsSlightly water soluble.
Reactivity Profile2-Chlorotoluene may be incompatible with strong oxidizing and reducing agents. Also may be incompatible with amines, nitrides, azo/diazo compounds, alkali metals, and epoxides. Reacts violently with dimethyl sulfoxide .
HazardToxic by inhalation. Eye, skin, and upper respiratory tract irritant.
Health HazardInhalation of vapor may cause respiratory irrtation. Prolonged and repeated vapor exposures may produce systemic toxic effects.
Flammability and ExplosibilityFlammable
Safety ProfileModerately toxic by unspecified routes. Flammable when exposed to heat or flame. When heated to decomposition it emits toxic fumes of Cl-. See also TOLE CHLORIDE and CHLORINATED HYDROCARBONS, AROMATIC.
Potential Exposureo-Chlorotoluene is widely used as a solvent and intermediate in the synthesis of dyes, synthetic rubber; pharmaceuticals; and other organic chemicals. Used as an insecticide, bactericide.
ShippingUN2238 Chlorotoluenes, Hazard Class: 3; Labels: 3-Flammable liquid.
Purification MethodsDry 2-chlorotoluene for several days with CaCl2, then distil it from Na using a glass helices-packed column. [Beilstein 5 IV 805.]
IncompatibilitiesIncompatible with acids, alkalis, oxidizers, reducing materials; water
Waste DisposalIn accordance with 40CFR165 recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.
Tag:2-Chlorotoluene(95-49-8) Related Product Information
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