| Identification | More | [Name]
Ethyl 2-methylnicotinate | [CAS]
1721-26-2 | [Synonyms]
2-METHYLNICOTINIC ACID ETHYL ESTER
ETHYL 2-METHYLNICOTINATE
3-Pyridinecarboxylic acid, 2-methyl-, ethyl ester
Ethyl 2-methylpyridine-3-carboxylate~2-Methylnicotinic acid ethyl ester
ethyl 2-methylpyridine-3-carboxylate
2-Methyl-3-pyridinecarboxylic acid ethyl ester
2-Methylpyridine-3-carboxylic acid ethyl ester | [EINECS(EC#)]
217-013-4 | [Molecular Formula]
C9H11NO2 | [MDL Number]
MFCD00006336 | [Molecular Weight]
165.19 | [MOL File]
1721-26-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
146-147 °C | [Boiling point ]
126-127 °C24 mm Hg(lit.) | [density ]
1.072 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.505(lit.)
| [Fp ]
217 °F
| [storage temp. ]
Inert atmosphere,Room Temperature | [form ]
Liquid | [pka]
4.02±0.10(Predicted) | [color ]
Clear colorless to orange | [Water Solubility ]
Slightly soluble in water. | [λmax]
268nm(EtOH)(lit.) | [BRN ]
118200 | [InChI]
InChI=1S/C9H11NO2/c1-3-12-9(11)8-5-4-6-10-7(8)2/h4-6H,3H2,1-2H3 | [InChIKey]
TZORNSWZUZDUCU-UHFFFAOYSA-N | [SMILES]
C1(C)=NC=CC=C1C(OCC)=O | [CAS DataBase Reference]
1721-26-2(CAS DataBase Reference) | [NIST Chemistry Reference]
Ethyl 2-methylnicotinate(1721-26-2) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [HS Code ]
29333990 | [Storage Class]
10 - Combustible liquids |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless liquid | [Uses]
Ethyl 2-methylpyridine-3-carboxylate was used in the preparation of amino esters such as ethyl 2(piperidinylaminomethyl)benzoate, ethyl 2-(N-benzyl-N-methylaminomethyl)benzoate, ethyl 2-(diethylaminomethyl)benzoate. | [Synthesis]
A method for the preparation of Ethyl 2-methylnicotinate, as follows: (1) 2.0 mol of 1,1,3,3-tetramethoxypropane was added into a reactor at room temperature, 2.5 mol of hydrochloric acid at a mass concentration of 20% was added with stirring, an |
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