| Identification | More | [Name]
Tulobuterol hydrochloride | [CAS]
56776-01-3 | [Synonyms]
alpha-[(tert-butylamino)methyl]-o-chlorobenzyl alcohol hydrochloride
TULOBUTEROL HCL
TULOBUTEROL HYDROCHLORIDE
1-(o-chlorophenyl)-2-tert-butylaminoethanolhydrochloride
2-chloro-alpha-(((1,1-dimethylethyl)amino)methyl)-benzenemethanohydrochl
alpha-((tert-butylamino)methyl)-o-chloro-benzylalcohohydrochloride
alpha-(tert-butylamino)methyl-2-chloro-benzylalcohohydrochloride
alpha-(tert-butylamino)methyl-2-chlorobenzylalcoholhydrochloride
c78
chlobamolhydrochloride
lobuterol
o-chloro-alpha-((tert-butylamino)methyl)benzylalcoholhydrochloride
TULOBUTEROL HG 99%
TULOBUTEROL HG
Atenos
Benzenemethanol, 2-chloro-a-[[(1,1-dimethylethyl)amino]methyl]-, hydrochloride (9CI)
Berachin
Brelomax
Bremax
Chlibamol | [EINECS(EC#)]
634-677-4 | [Molecular Formula]
C12H19Cl2NO | [MDL Number]
MFCD00214398 | [Molecular Weight]
264.19 | [MOL File]
56776-01-3.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. | [WGK Germany ]
3 | [RTECS ]
DN8785000 | [HS Code ]
2922.19.7000 |
| Hazard Information | Back Directory | [Uses]
Hydrochloride salt of Tulobuterol a sympathomimetic drug used as a transdermal patch, increases normal diaphragm muscle strength. A β-adrenergic receptor agonist, related structurally to Terbutaline (T109750). | [Definition]
ChEBI: Tulobuterol hydrochloride is an organic molecular entity. | [General Description]
Standard for Supelco MIP SPE cartridges. For more information request Supelco Literature T407075, T706019, T706030, T706020 | [in vivo]
In vivo effect of Tulobuterol is examined the on the contractility of diaphragm muscles prepared from mice (BALBs/c mice; 21.7 ± 0.2 g) treated with Endotoxin. Contractile parameters of force-frequency curves and twitch kinetics using untreated or treated diaphragm muscles at 0 (E0) and 4 (E4) hours after E. coli endotoxin (20 mg/kg) administration are measured. E0 and E4 diaphragm muscles are analyzed at 0, 12, and 24 h after transdermal Tulobuterol treatment. The force-frequency curves of E0 and E4 diaphragm muscles at three time points are not significantly changed each other, indicating that Tulobuterol patch restores the muscle contractility. Thus, diaphragm muscle contractility is maintained during 4 h of endotoxin administration with Tulobuterol patch for over 24 h[3]. |
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