Methylthiouracil
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- CAS-Nr.
- 56-04-2
- Bezeichnung:
- Methylthiouracil
- Englisch Name:
- Methylthiouracil
- Synonyma:
- MZU;Mtu;Thyril;Alkiron;Basecil;Muracil;Muracin;Orcanon;Thioryl;Thiuryl
- CBNumber:
- CB3108758
- Summenformel:
- C5H6N2OS
- Molgewicht:
- 142.18
- MOL-Datei:
- 56-04-2.mol
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Methylthiouracil Eigenschaften
- Schmelzpunkt:
- ~330 °C (dec.)(lit.)
- Dichte
- 1.291 (estimate)
- Brechungsindex
- 1.6430 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- Löslichkeit
- DMSO (Heated), Methanol (Slightly, Heated)
- Aggregatzustand
- Liquid
- pka
- pKa 8.2 (Uncertain)
- Farbe
- Clear colorless to yellow
- Wasserlöslichkeit
- INSOLUBLE
- Merck
- 14,6128
- BRN
- 115648
- Stabilität:
- Incompatible with strong oxidizing agents, iodine, metals.
- InChIKey
- HWGBHCRJGXAGEU-UHFFFAOYSA-N
- CAS Datenbank
- 56-04-2(CAS DataBase Reference)
- IARC
- 2B (Vol. Sup 7, 79) 2001
- NIST chemische Informationen
- 6-Methyl-2-thiouracil(56-04-2)
- EPA chemische Informationen
- Methylthiouracil (56-04-2)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn,Xi |
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| R-Sätze: |
22-40 |
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| S-Sätze: |
36/37-45 |
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| RIDADR |
UN 3077 9 / PGIII |
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| WGK Germany |
3 |
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| RTECS-Nr. |
YR0875000 |
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| Hazard Note |
Irritant/Possible Carcinogen |
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| TSCA |
Yes |
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| HS Code |
29335995 |
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| Giftige Stoffe Daten |
56-04-2(Hazardous Substances Data) |
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| Toxizität |
MLD in rabbits (mg/kg): 2486 orally (Simon) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H317 |
Kann allergische Hautreaktionen verursachen. |
Sensibilisierung der Haut |
Kategorie 1A |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P272 |
Kontaminierte Arbeitskleidung nicht außerhalb des Arbeitsplatzes tragen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P333+P313 |
Bei Hautreizung oder -ausschlag: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen. |
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Methylthiouracil Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R40:Verdacht auf krebserzeugende Wirkung.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Chemische Eigenschaften
white powder
Verwenden
6-?Methyl-?2-?thiouracil is a derivative of methylthiouracil (M330710), a competitive inhibitor of Nitric Oxide Synthase (NOS). Potential anti-inflammatory agent.
Allgemeine Beschreibung
White crystalline powder with an odor of onions and a bitter taste. A saturated aqueous solution is neutral or slightly acidic.
Air & Water Reaktionen
Insoluble in water.
Reaktivität anzeigen
Methylthiouracil reacts with strong oxidizing agents. Forms complexes with metals and is oxidized by iodine and other sulfhydryl oxidizing agents .
Brandgefahr
Flash point data for Methylthiouracil are not available. Methylthiouracil is probably combustible.
Sicherheitsprofil
Confirmed carcinogen
with experimental carcinogenic,
neoplastigenic, tumorigenic, and teratogenic
data. Poison by intraperitoneal route.
Moderately toxic by ingestion. Human
teratogenic and reproductive effects by an
unspecified route: developmental
abnormalities of the endocrine system and
effects on newborn including neonatal
measures or effects. Experimental
reproductive effects. Used to treat
hyperthyroidism. When heated to
decomposition it emits very toxic fumes of
NOx and SOx.
läuterung methode
Crystallise the thiouracil from a large volume of H2O. Purify it further by dissolving in base, adding charcoal, filtering and acidifying with AcOH. Suspend the wet solid (ca 100g) in boiling H2O (1L), stir and add AcOH (20mL), stir and refrigerate. Collect the product, wash it with cold H2O (4 x 200mL), drain it for several hours then place it in an oven at 70o to constant weight. [IR: Short & Thompson J Chem Soc 168 1952, Foster & Snyder Org Synth Coll Vol IV 638 1063, Beilstein 24 III/IV 1289.]
Methylthiouracil Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Methylthiouracil Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 402)Lieferanten
56-04-2(Methylthiouracil)Verwandte Suche:
- LABOTEST-BB LT00848091
- AURORA KA-4696
- METHIOCIL
- METHYLTHIOURACIL
- 4-OXO-2-MERCAPTO-6-METHYLPYRIMIDINE
- 4-HYDROXY-2-MERCAPTO-6-METHYLPYRIMIDINE
- 4-HYDROXY-6-METHYL-2-THIOPYRIMIDINE
- 4-METHYL-2-THIOURACIL
- 4(6)-METHYL-2-THIOURACIL
- AKOS BC-0693
- 6-METHYL-4-OXY-2-THIOPYRIMIDINE
- 6-METHYL-2-THIOURACIL
- 6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-4-ONE
- 6-methyl-2-thioxo-2,3-dihydro-1h-pyrimidin-4-one
- 6-HYDROXY-2-MERCAPTO-4-METHYLPYRIMIDINE
- 2,3-dihydro-6-methyl-2-thioxo-4(1h)-pyrimidinon
- 2,3-Dihydro-6-methyl-2-thioxo-4(1H)-pyrimidinone
- 2-THIO-6-METHYLURACIL
- 6-METHYL-2-THIOURACYLE
- Methylthiouracilum
- 6-METHYL-2-THIOURACILE VETRANAL, 250
- 4-METHYL-2-THIOURACIL 98%
- 4(1H)-Pyrimidinone, 2,3-dihydro-6-methyl-2-thioxo- (9CI)
- 6-METHYL-2-THIOURACIL,REAGENT
- 6 methyl2 thiouracile
- methylthiouracil，MTU
- 4-Hydroxy-2-mercapto 6-methylpyrimidine, 6-Methyl-2-thiouracil
- 6-Methyl-2-sulfanylidene-1H-pyrimidin-4-one
- 4-Hydroxy-2-mercapto-6-methylpyrimidine,98%
- 6-methyl-2-thioxo-1H-pyrimidin-4-one
- MZU
- 6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
- 6-Methyl-2-thiouracil,4-Hydroxy-2-mercapto 6-methylpyrimidine, MZU
- 4-Hydroxy-2-mercapto-6-methylpyrimidine,4-Hydroxy-2-mercapto 6-methylpyrimidine, 6-Methyl-2-thiouracil, MZU
- 6-Methyl-2-thioxo-2,3-dihydropyriMidin-4(1H)-one (Methylthiouracil)
- 6-Methyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-4-one, 4-Hydroxy-2-mercapto-6-methylpyrimidine
- 4-Hydroxy-2-Mercapto-6-MethylpyriMidin
- 2,3-Dihydro-6-methyl-2-thioxopyrimidin-4(1H)-one, 4-Hydroxy-2-mercapto-6-methylpyrimidine
- 2-Mercapto-4-hydroxy-6-methylpyrimidine
- 2-Mercapto-6-methyl-4-pyrimidone
- 2-Mercapto-6-methylpyrimid-4-one
- 2-Thio-4-oxo-6-methyl-1,3-pyrimidine
- 2-Thio-6-methyl-1,3-pyrimidin-4-one
- 2-Thiouracil, 6-methyl-
- 4(1H)-Pyrimidinone, 2,3-dihydro-6-methyl-2-thioxo-
- 4-Methylthiouracil
- 6-Methyl-2-thiouracil puruM, >=98.0% S basis (eleMental analysis)
- Methyl thiourea pyriMidine
- 6-Methyl-2-thi
- 6-Methyl-2-mercaptouracil
- 6-Methyl-2-thio-2,4(1H,3H)-pyrimidinedione
- 6-methyl-2-thio-2,4-(1h3h)-pyrimidinedione
- 6-methyl-2-thio-uraci
- 6-Methyl-2-thiouracyl
- 6-Methyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone
- 6-Methylthiouracil
- 6-Metil-tiouracile
- 6-Thio-4-methyluracil
