5,7-Dihydroxy-2-(4-methoxyphenyl)-4-benzopyron
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- CAS-Nr.
- 480-44-4
- Bezeichnung:
- 5,7-Dihydroxy-2-(4-methoxyphenyl)-4-benzopyron
- Englisch Name:
- Acacetin
- Synonyma:
- Abietic;acacetine;5,7-dihydroxy-4’-methoxy-flavon;ACACETIN;LY 064233;NSC 76061;LINARIGENIN;Linarisenin;ACACETIN hplc;Acacetin, >98%
- CBNumber:
- CB9316535
- Summenformel:
- C16H12O5
- Molgewicht:
- 284.26
- MOL-Datei:
- 480-44-4.mol
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5,7-Dihydroxy-2-(4-methoxyphenyl)-4-benzopyron Eigenschaften
- Schmelzpunkt:
- 260-265 °C(lit.)
- Siedepunkt:
- 346.76°C (rough estimate)
- Dichte
- 1.2160 (rough estimate)
- Brechungsindex
- 1.6200 (estimate)
- storage temp.
- 2-8°C
- Löslichkeit
- DMSO (Slightly), Methanol (Very Slightly, Heated)
- Aggregatzustand
- Solid
- pka
- 6.51±0.40(Predicted)
- Farbe
- Light Yellow to Green-Yellow to Dark Yellow
- maximale Wellenlänge (λmax)
- 335nm(EtOH)(lit.)
- Merck
- 14,13
- BRN
- 277879
- InChIKey
- DANYIYRPLHHOCZ-UHFFFAOYSA-N
- LogP
- 2.443 (est)
- CAS Datenbank
- 480-44-4(CAS DataBase Reference)
5,7-Dihydroxy-2-(4-methoxyphenyl)-4-benzopyron Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Acacetin is an O-methylated flavone found in various plants. It is reported to demonstrate spasmolytic, antinociceptive, anti-inflammatory, and antioxidant activity in various research models.
Chemische Eigenschaften
Yellow Solid
Verwenden
VEGF expression inhibitor and tumor angiogenesis. A flavonoid with antiaggregatory activity in human blood.
Definition
ChEBI: A monomethoxyflavone that is the 4'-methyl ether derivative of apigenin.
Allgemeine Beschreibung
Acacetin belongs to the category of naturally occurring plant pigments called flavonoids found in vascular plants. It was first reported to be extracted from the leaves of
Robinia pseuducacia. It has been used as an active component of traditional Chinese medicine Xuelianhua.
Enzyminhibitor
This naturally occurring flavone (FW = 286.27 g/mol; CAS 480-44-4), also known as 5,7-dihydroxy-4’-methoxyflavone and 7-O-methylapigenin, and systematically named as 5,7-dihydroxy-2-(4-methoxyphenyl)-chromen-4- one, from the black locust Robinia pseudoacacia is the aglycon of linarin and acaciin and is biosynthesized by apigenin 4'-O-methyltransferase from S-adenosyl-methionine and 5,7,4’-trihydroxyflavone (apigenin), yielding Sadenosylhomocysteine and acacetin. The chemical synthesis of acacetin was accomplished by Robert Robinson, who was awarded the 1947 Nobel Prize in Chemistry for his work on alkaloids and organic synthesis. Target(s): glutathione S-transferase; xanthine oxidase, Ki = 0.11 μM; CYP1A; CYP1B1; glutathione-disulfide reductase; DNA topoisomerase I; [myosin light-chain] kinase; and protein-tyrosine kinase, or non-specific protein-tyrosine kinase.
5,7-Dihydroxy-2-(4-methoxyphenyl)-4-benzopyron Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5,7-Dihydroxy-2-(4-methoxyphenyl)-4-benzopyron Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 371)Lieferanten
480-44-4(5,7-Dihydroxy-2-(4-methoxyphenyl)-4-benzopyron)Verwandte Suche:
Hexadecylpalmitat
Etidronisure
Triclosan
2-(3,6-Dihydroxy-2,4,5,7-tetrabromxanthen-9-yl)-benzoesure
4-Methoxy-anilin
5,7-Dihydroxy-2-phenyl-4H-benzo[b]pyran-4-on
Anisaldehyd
Anisol
(Trifluormethoxy)benzol
(E,E)-Farnesol
3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyron
3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4-benzopyron
5,7-Dihydroxy-2-(3,4,5-trimethoxyphenyl)-4-benzopyron
2-(3,4-Dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-4-benzopyron
5-Hydroxy-3,7-dimethoxy-2-(4-methoxyphenyl)-4-benzopyron
Diosmin
5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyron
5,6,7,8-Tetramethoxy-2-(4-methoxyphenyl)-4-benzopyron
- 5,7-DIHYDROXY-4'-METHOXYFLAVONE
- LINARIGENIN
- METHYL-4'-APIGENIN
- ACACETIN
- 5,7-dihydroxy-2-(4-methoxyphenyl)-4-benzopyrone
- ACACETIN(METHYL-4'-APIGENIN)(RG)
- ACACETIN WITH HPLC
- 4'-O-Methylapigenin
- 5,7-Dihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
- Linarisenin
- Acacetin,5,7-Dihydroxy-4′-methoxyflavone
- 5,7-DIHYDROXY-2-(4-METHOXYPHENOL)-1-BENZOPYRAN-4-ONE
- 1-BENZOPYRAN-4-ONE,5,7-DIHYDROXY-2-(4-METHOXYPHENOL)-
- 2-(4-Methoxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
- apisenin4’-methylether
- buddleoflavonol
- ACACETIN hplc
- LY 064233
- NSC 76061
- ACACETIN >= 97.0% (HPLC)
- 5,7-dihydroxy-2-(4-methoxyphenyl)-4h-1-benzopyran-4-on
- 5,7-dioxy-4’-methoxyflavone
- Acacetin 480-44-4
- large stock Acacetin 480-44-4
- 7-hydroxy-2-(4-methoxyphenyl)-4-oxo-1-benzopyran-5-olate
- Acacetin, >98%
- 5,7-Dihydroxy-2-(4-methoxyphenyl)-4H-chromen
- Acacetin, 98%, From Acacia farnesiana (L.) Willd.
- 4'-Methoxyapigenin
- 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-methoxyphenyl)-
- O sand and paxil
- 4'-methoxy-5,7-dihydroxy flavone
- Abietic
- 5,7-dihydroxy-4’-methoxy-flavon
- acacetine
- Acacetin Powder
- 480-44-4
- Food Residue Analysis
- Food & Beverage Standards
- Chromatography
- Analytical Chromatography Product Catalog
- Analytical Standards
- Miscellaneous Reagents
- inhibitor
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Tri-substituted Flavones
- Aromatics
- Heterocycles
