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Thioproperazine

CAS No.
316-81-4
Chemical Name:
Thioproperazine
Synonyms
Vontil;Megeptil;Mazeptyl;Majeptyl;Cephalmin;Sulfenazin;hioproperazine;thioproperazine;N'-(4-chlorophenyl)-N,N-dimethylcarbamimidic acid methyl ester;N,N-Dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-sulfonamide
CBNumber:
CB3912908
Molecular Formula:
C22H30N4O2S2
Molecular Weight:
446.63
MDL Number:
MFCD00867741
MOL File:
316-81-4.mol
MSDS File:
SDS
Last updated:2025-10-29 15:43:00
Product description Number Pack Size Price
N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine-2-sulfonamide AldrichCPR PH003261 1MG $172
Thioproperazine 97% CD11146489 100mg $416
Thioproperazine 97% CD11146489 250mg $665
Thioproperazine 97% CD11146489 1g $1664

Thioproperazine Properties

Melting point 140°
Boiling point 612.2±65.0 °C(Predicted)
Density 1.1476 (rough estimate)
refractive index 1.6200 (estimate)
storage temp. Sealed in dry,Room Temperature
form Solid
pka 7.65±0.10(Predicted)
color Light yellow to yellow
FDA UNII YJ050AQ56X
ATC code N05AB08
NIST Chemistry Reference Thioproperazine(316-81-4)

SAFETY

Risk and Safety Statements

Toxicity LD50 oral in mouse: 830mg/kg

Thioproperazine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PH003261 N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine-2-sulfonamide AldrichCPR 316-81-4 1MG $172 2023-06-20 Buy
Crysdot CD11146489 Thioproperazine 97% 316-81-4 100mg $416 2021-12-16 Buy
Crysdot CD11146489 Thioproperazine 97% 316-81-4 250mg $665 2021-12-16 Buy
Crysdot CD11146489 Thioproperazine 97% 316-81-4 1g $1664 2021-12-16 Buy
Product number Packaging Price Buy
PH003261 1MG $172 Buy
CD11146489 100mg $416 Buy
CD11146489 250mg $665 Buy
CD11146489 1g $1664 Buy

Thioproperazine Chemical Properties,Uses,Production

Originator

Majeptil,Specia,France,1960

Definition

ChEBI: A phenothiazine derivative in which the phenothiazine tricycle has a dimethylaminosulfonyl substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at N-10.

Manufacturing Process

A solution of 3-dimethylsulfamoylphenthiazine (5 g) in anhydrous xylene (100 cc) is heated under reflux for 1 hour with sodamide (0.67 g). 3-(4-methyl-1- piperazinyl)-1-chloropropane (3.2 g) in solution in anhydrous xylene (20 cc) is added and the mixture heated under reflux for 5 hours. After treatment of the reaction products, a crude oily base (2.5 g) is obtained after treatment. By the addition of a solution of fumaric acid in ethanol to an ethanolic solution of the base, 3-dimethylsulfamoyl-10-(3-41-methyl-11-piperazinylpropyl)- phenthiazinediacid fumarate (2.6 g) is obtained, melting point 182°C. The base recrystallized from ethyl acetate melts at about 140°C.

Therapeutic Function

Neuroleptic, Antiemetic

Thioproperazine Preparation Products And Raw materials

Raw materials

Preparation Products

Thioproperazine Suppliers

Global( 32)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-173 9270 1263 1057@dideu.com China 3999 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49975 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30229 58
Shaanxi Didu New Materials Co. Ltd
+86-89586680 +86-13289823923 1026@dideu.com China 9080 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 39035 58
SUZHOU SENFEIDA CHEMICAL CO.,LTD
+86-0512-83500002 +8618662433356 3899766280@qq.com China 26362 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+86-18621343501; +undefined18621343501 product@acmec-e.com China 33337 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580 cooperation@kean-chem.com China 40066 58

View Lastest Price from Thioproperazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Thioproperazine pictures 2025-12-05 Thioproperazine
316-81-4
US $283.00-419.00 / mg 99.45% 10g TargetMol Chemicals Inc.
Thioproperazine pictures 2024-05-22 Thioproperazine
316-81-4
US $1.00 / G 1G 98% 100G Shaanxi Dideu Medichem Co. Ltd
  • Thioproperazine pictures
  • Thioproperazine
    316-81-4
  • US $283.00-419.00 / mg
  • 99.45%
  • TargetMol Chemicals Inc.

Thioproperazine Spectrum

thioproperazine N,N-Dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-sulfonamide 10H-Phenothiazine-2-sulfonamide, N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]- Cephalmin Phenothiazine-2-sulfonamide, N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]- Sulfenazin N'-(4-chlorophenyl)-N,N-dimethylcarbamimidic acid methyl ester hioproperazine Majeptyl Mazeptyl Megeptil Vontil N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine-2-sulfonamide 316-81-4 C22H30N4O2S2