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STACHYDRINE HYDROCHLORIDE

CAS No.
4136-37-2
Chemical Name:
STACHYDRINE HYDROCHLORIDE
Synonyms
StachydrineHCl;Stachydrine chloride;Stachydrine hydrochL;Herba leonurl extract;Cadabine hydrochloride;Stachydrine hydrochlor;Stachydrine hydrochlori;Stachydrine chloride-RM;Stachytine hydrochloride;Stachydrine hydrichloride
CBNumber:
CB4290780
Molecular Formula:
C7H14ClNO2
Molecular Weight:
179.64
MDL Number:
MFCD21609192
MOL File:
4136-37-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-22 18:57:36
Product description Number Pack Size Price
Stachydrine chloride phyproof? Reference Substance PHL89799 25MG $327
Stachydrine Hydrochloride S0358 10mg $29
Stachydrine (hydrochloride) 20506 100mg $63
Stachydrine (hydrochloride) 20506 1g $365
Stachydrine (hydrochloride) 20506 250mg $139
More product size

STACHYDRINE HYDROCHLORIDE Properties

Melting point 225°C
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Methanol (Slightly), Water (Slightly)
form Solid
color White to Off-White
Water Solubility Soluble in water
Merck 14,8771
Stability Hygroscopic
InChI InChI=1S/C7H13NO2.ClH/c1-8(2)5-3-4-6(8)7(9)10;/h6H,3-5H2,1-2H3;1H
InChIKey DUNMULOWUUIQIL-UHFFFAOYSA-N
SMILES C1(CCC[N+]1(C)C)C([O-])=O.Cl
CAS DataBase Reference 4136-37-2(CAS DataBase Reference)
FDA UNII 19Z024IC5E

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Risk Statements  20-22
Safety Statements  22-45-36/37/39
HS Code  29339900

STACHYDRINE HYDROCHLORIDE price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL89799 Stachydrine chloride phyproof? Reference Substance 4136-37-2 25MG $327 2026-03-19 Buy
TCI Chemical S0358 Stachydrine Hydrochloride 4136-37-2 10mg $29 2026-03-19 Buy
Cayman Chemical 20506 Stachydrine (hydrochloride) 4136-37-2 100mg $63 2024-03-01 Buy
Cayman Chemical 20506 Stachydrine (hydrochloride) 4136-37-2 1g $365 2024-03-01 Buy
Cayman Chemical 20506 Stachydrine (hydrochloride) 4136-37-2 250mg $139 2024-03-01 Buy
Product number Packaging Price Buy
PHL89799 25MG $327 Buy
S0358 10mg $29 Buy
20506 100mg $63 Buy
20506 1g $365 Buy
20506 250mg $139 Buy

STACHYDRINE HYDROCHLORIDE Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder, easily soluble in methanol and water, derived from motherwort.

Uses

Stachydrine Chloride is a constituent of the Chinese herb leonurus heterophyllus sweet. its used in clinics to support blood circulation and dispel blood stasis.

Biological Activity

stachydrine is an anti-metastatic agent.stachydrine, a pyrrolidine betaine, was first isolated from seed husk and the pulp of the fruit of c. leonurus, and many other asian plants and fruits.

in vitro

the aim of a previous study was to investigate the effects of stachydrine (sta) on norepinephrine (ne) induced hypertrophy and the changes of calcium transients in neonatal rat cardiomyocytes. results showed that ne treatment could increase protein synthesis, cell surface area, the expression level of β-mhc and β/α-mhc ratio and these effects were attenuated by sta treatment. in addition, ne-induced hypertrophy was associated with accelerated decay of ca2+-transient, increased phospholamban expression, increased ca2+-transient amplitude, hyper-phosphorylation, increased intracellular camp level, as well as pka overactivation. all of these effects could be inhibited by sta treatment significantly [1].

in vivo

previous study evaluated the effect of stachydrine on the expression of caspase-9 and 12 in rats with unilateral ureteral obstruction. results showed that degree of renal interstitial fibrosis, serum creatinine, blood urea nitrogen, the renal tubular interstitial damage index, and expression of caspase-9 and 12 in the stachydrine-treatment groups were significantly decreased [2].

target

IL Receptor | T-bet | RORγt | GATA-3 | Foxp3

IC 50

p65; Human Endogenous Metabolite

References

[1] zhang, c. ,shan, x.-l.,liao, y.-l., et al. effects of stachydrine on norepinephrine-induced neonatal rat cardiac myocytes hypertrophy and intracellular calcium transients. bmc complement. altern. med. 14, 474 (2014).
[2] zhang c, lu y, zhou yj, tong qq, qu c, kang tj. the effect of stachydrine on the expression of caspase-12 in rats with unilateral ureteral obstruction. j urol. 2014 nov;192(5):1549-54.

147-85-3
74-88-4
4136-37-2
Synthesis of STACHYDRINE HYDROCHLORIDE from L-Proline and Iodomethane

STACHYDRINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 359)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
+86-29-81139210 +86-18192627656 1059@dideu.com China 3590 58
Hebei Yanxi Chemical Co., Ltd.
+8618531123677 faithe@yan-xi.com China 5853 58
BINBO BIOLOGICAL CO.,LTD
+8618629063126 info@binbobiological.com China 477 58
Shaanxi Xianhe Biotech Co., Ltd
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Chengdu Biopurify Phytochemicals Ltd.
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Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58

View Lastest Price from STACHYDRINE HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
STACHYDRINE HYDROCHLORIDE pictures 2026-04-29 STACHYDRINE HYDROCHLORIDE
4136-37-2
US $0.00 / kg 1kg 0.99 1000kg Shaanxi Xianhe Biotech Co., Ltd
Stachydrine hydrochloride pictures 2026-04-28 Stachydrine hydrochloride
4136-37-2
US $0.00 / KG 1KG ≥98% HPLC 1000KG Changsha Staherb Natural Ingredients Co., Ltd.
Stachydrine Hydrochloride pictures 2026-04-22 Stachydrine Hydrochloride
4136-37-2
US $46.00 / mg 99.92% 10g TargetMol Chemicals Inc.
STACHYDRINE HYDROCHLORIDE (S)-2-carboxy-1,1-dimethylpyrrolidinium chloride StachydrineHCl Stachydrine hydrichloride 2-Carboxy-1,1-dimethylpyrrolidinium chloride Stachydrine chloride Stachydrine hydrochlori Stachydrine chloride 2-Carboxy-1,1-dimethylpyrrolidinium chloride Stachydrine hydrochloride, froM Leonurus japonicus Hydrochloric acid Stachydrine Stachydrine hydrochloride, 98%, from Leonurus japonicus Herba leonurl extract Stachydrine hydrochloride, 98%, from Leonurus artemisia (Lour.) S. Y. Hu Stachytine hydrochloride Stachydrine hydrochL Pyrrolidinium, 2-carboxy-1,1-dimethyl-, chloride, (S)- STACHYDRINE HYDROCHLORIDE CAS : 4136-37-2 (S)-2-Carboxy-1,1-dimethylpyrrolidin-1-ium chloride Cadabine hydrochloride Stachydrine chloride-RM Stachydrine Hydrochloride, 10 mM in DMSO Stachydrine hydrochlor 4136-37-2 C7H13NO2HCl Ammonium Chlorides (Quaternary) Quaternary Ammonium Compounds Ammonium Chlorides (Quaternary) Quaternary Ammonium Compounds