ChemicalBook >> CAS DataBase List >>(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride
- CAS No.
- 101152-94-7
- Chemical Name:
- (1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride
- Synonyms
- IXEL;F 2207;Dalcipran;TOLEDOMIN;cis-(+-)-d;MIDALCIPRAN;Milnacipran HCI;MILNACIPRAN HCL;Chiral Reagents;Milnacipran HCl (1)
- CBNumber:
- CB4423243
- Molecular Formula:
- C15H23ClN2O
- Molecular Weight:
- 282.81
- MDL Number:
- MFCD00901293
- MOL File:
- 101152-94-7.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
| Melting point | 179-1810C |
|---|---|
| Flash point | 9℃ |
| storage temp. | 2-8°C |
| solubility | H2O: 19 mg/mL |
| form | solid |
| color | white |
| Merck | 14,6194 |
| CAS DataBase Reference | 101152-94-7(CAS DataBase Reference) |
| FDA UNII | RNZ43O5WW5 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P301+P310 | |||||||||
| Hazard Codes | Xn,T,F | |||||||||
| Risk Statements | 22-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 7-16-36/37-45 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | GZ1014010 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29242990 | |||||||||
| Toxicity | LD50 orally in mice: 237 mg/kg (Bonnaud) | |||||||||
| NFPA 704 |
|
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M-145 | Milnacipran hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? | 101152-94-7 | 1mL | $213 | 2024-03-01 | Buy |
| Sigma-Aldrich | M1318 | Milnacipran hydrochloride ≥98% (HPLC), solid | 101152-94-7 | 10mg | $242 | 2024-03-01 | Buy |
| Sigma-Aldrich | M1318 | Milnacipran hydrochloride ≥98% (HPLC), solid | 101152-94-7 | 50mg | $526.2 | 2024-03-01 | Buy |
| TCI Chemical | M2133 | Milnacipran Hydrochloride >98.0%(HPLC)(T) | 101152-94-7 | 50mg | $18 | 2024-03-01 | Buy |
| TCI Chemical | M2133 | Milnacipran Hydrochloride >98.0%(HPLC)(T) | 101152-94-7 | 500mg | $94 | 2024-03-01 | Buy |
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
Uses
antibacterial
Uses
Antidepressant. A selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia.
Definition
ChEBI: Milnacipran hydrochloride is a member of acetamides.
General Description
Milnacipran, sold under the brand names Savella?, Ixel?, Dalcipran?, or Toledomin, is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the treatment of depression. In 2009, the US Food and Drug Administration (FDA) approved milnacipran for management of the chronic pain disorder fibromyalgia, making it only the third drug approved in the US for this indication besides duloxetine and pregabalin.
Biological Activity
Orally active 5-HT and noradrenalin re-uptake inhibitor (SNRI) (IC 50 values are 203 and 100 nM respectively) that displays no affinity at a range of other receptors. Causes adaptive changes to α 1 -adrenergic and 5-HT 2A serotonergic systems when administered repeatedly. Exhibits antidepressive and antinociceptive activities in vivo .
Biochem/physiol Actions
Serotonin and norepinephrine reuptake inhibitor (SNRI)
storage
+4°C
(1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 329)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Shanghai Yingrui Biopharma Co.,Ltd | 21-33585366 | export01@shyrchem.com | CHINA | 1320 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | mcbio_sales@163.com | China | 2255 | 58 |
View Lastest Price from (1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-07-16 | Milnacipran Hydrochloride
101152-94-7
|
US $200.00 / g | 10g | 99% | 25kg/ month | Wuhan Qiami Technology Co., Ltd | |
 |
2021-07-13 | Milnacipran hydrochloride solution
101152-94-7
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-09 | Milnacipran hydrochloride solution
101152-94-7
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Milnacipran Hydrochloride
101152-94-7
- US $200.00 / g
- 99%
- Wuhan Qiami Technology Co., Ltd
-
- Milnacipran hydrochloride solution
101152-94-7
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Milnacipran hydrochloride solution
101152-94-7
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
101152-94-7((1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride)Related Search:
1of4
cis-(+-)-2-(aminomethyl)-n,n-diethyl-1-phenylcyclopropanecarboxamidemonohydr
cis-(+-)-d
Milnacipran Hydrochloride (Subject to patent free)
(1R,2S)-rel-2(Amino-methyl)-N,N-diethyl-1-phenyl-cyclopropanecarboxamide, Monohydrochloride
Dalcipran
F 2207
IXEL
(1R,2S)-REL-2-(AMINOMETHYL)-N,N-DIETHYL-1-PHENYLCYCLOPROPANECARBOXAMIDE HYDROCHLORIDE
(1R,2S)-REL-2-(AMINOMETHYL)-N,N-DIMETHYL-1-PHENYLCYCLOPROPANECARBOXAMIDE HYDROCHLORIDE
Milnacipran hydrochloride solution
F 2207, Midalcipran, Toledomin, (1R,2S)-rel-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide monohydrochloride
rel-2α*-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1α*-carboxamide·hydrochloride
rac Milnacipran Hydrochloride
(1R*,2S*)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamidehydrochloride
Milnacipran HCI
Milnacipran Hydrochloride Tablets
Milnacipran HCl (1)
TOLEDOMIN
MILNACIPRAN HCL
MILNACIPRAN HYDROCHLORIDE
MIDALCIPRAN
MIDALCIPRAN HYDROCHLORIDE
1-phenyl-1-(diethylaminocarbonyl)-2-(aminomethyl)cyclopropanehydrochloride
2-(aminomethyl)-n,n-diethyl-1-phenyl-cyclopropanecarboxamidmonohydrochlori
2-(aminomethyl)-N,N-diethyl-1-phenyl-1-cyclopropanecarboxamide hydrochloride
Milnacipran-d5 HCl (and Enantiomer)
Milancipran Hydrochloride
MilnacipranHydrochloride>
Milnacipran Hydrochloride (250 mg)
Cyclopropanecarboxamide, 2-(aminomethyl)-N,N-diethyl-1-phenyl-, hydrochloride (1:1), (1R,2S)-rel-
Milnacipran Hydrochloride Impurities
Milnacipran hydrochlorideQ: What is
Milnacipran hydrochloride Q: What is the CAS Number of
Milnacipran hydrochloride Q: What is the storage condition of
Milnacipran hydrochloride Q: What are the applications of
Milnacipran hydrochloride
Chiral Reagents
Milnacipran hydrochloride, 98%, Serotonin and norepinephrine reuptake inhibitor
RSYYMilnacipranhydrochloride
Minapram hydrochloride
101152-94-7
C15H22N2OHClC15H23ClN2O
C15H23ClN2O
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