1,4-Dihydroxynaphthalene
- CAS No.
- 571-60-8
- Chemical Name:
- 1,4-Dihydroxynaphthalene
- Synonyms
- NAPHTHALENE-1,4-DIOL;1,4-NAPHTHALENEDIOL;1,4-NDO;1.4-Dihydroxyn;1,4-naphthoquinol;1,4-NAPTHALENEDIOL;Hydronaphthoquinone;Naphthohydroquinone;Naphthalin-1,4-diol;1,4-Naphththalenediol
- CBNumber:
- CB4756341
- Molecular Formula:
- C10H8O2
- Molecular Weight:
- 160.17
- MDL Number:
- MFCD00003977
- MOL File:
- 571-60-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1,4-Dihydroxynaphthalene technical, ≥90% (HPLC) | 70430 | 10g | $172 |
| 1,4-Dihydroxynaphthalene >97.0%(GC)(T) | D0589 | 5g | $117 |
| 1,4-Dihydroxynaphthalene >97.0%(GC)(T) | D0589 | 25g | $353 |
| Naphthohydroquinone ≥98% | CS-0197295 | 5g | $35 |
| Naphthohydroquinone ≥98% | CS-0197295 | 25g | $78 |
| More product size | |||
| Melting point | 191-192 °C (dec.) |
|---|---|
| Boiling point | 246.06°C (rough estimate) |
| Density | 1.0924 (rough estimate) |
| refractive index | 1.5178 (estimate) |
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | crystals |
| pka | pK1:9.37;pK2:10.93 (26°C,μ=0.65) |
| color | Grey |
| Water Solubility | slightly soluble |
| BRN | 1307689 |
| InChI | 1S/C10H8O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,11-12H |
| InChIKey | PCILLCXFKWDRMK-UHFFFAOYSA-N |
| SMILES | Oc1ccc(O)c2ccccc12 |
| CAS DataBase Reference | 571-60-8(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | AML1P6T42C |
| NIST Chemistry Reference | 1,4-Naphthalenediol(571-60-8) |
| EPA Substance Registry System | 1,4-Naphthalenediol (571-60-8) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H318-H335-H412 | |||||||||
| Precautionary statements | P261-P273-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn,T | |||||||||
| Risk Statements | 22-37/38-41-43-36/37/38-25 | |||||||||
| Safety Statements | 26-39-45-36/37/39-28A-24 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | QJ4730000 | |||||||||
| F | 8-10-16-23 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2921450090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Chronic 3 Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
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| NFPA 704 |
|
1,4-Dihydroxynaphthalene price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 70430 | 1,4-Dihydroxynaphthalene technical, ≥90% (HPLC) | 571-60-8 | 10g | $172 | 2026-04-30 | Buy |
| TCI Chemical | D0589 | 1,4-Dihydroxynaphthalene >97.0%(GC)(T) | 571-60-8 | 5g | $117 | 2026-04-30 | Buy |
| TCI Chemical | D0589 | 1,4-Dihydroxynaphthalene >97.0%(GC)(T) | 571-60-8 | 25g | $353 | 2026-04-30 | Buy |
| ChemScene | CS-0197295 | Naphthohydroquinone ≥98% | 571-60-8 | 5g | $35 | 2026-06-04 | Buy |
| ChemScene | CS-0197295 | Naphthohydroquinone ≥98% | 571-60-8 | 25g | $78 | 2026-06-04 | Buy |
1,4-Dihydroxynaphthalene Chemical Properties,Uses,Production
Chemical Properties
brown to greyish powder. 1,4-Naphthalenediol [571-60-8], mp 195℃, is synthesized by reduction of 1,4- naphthoquinone with sodium dithionite, or by hydrolysis of 4-amino-1-naphthol with 20 % sulfuric acid. It undergoes oxidation to give 1,4-naphthoquinone; amination to give 4-amino-1-naphthol; and methylation (MeOH – HCl) to give 4-methoxy-1-naphthol.
Uses
1,4-Dihydroxynaphthalene is frequently used in organic synthesis as a reagent. In particular, it is used in the synthesis of a pH independent and cell permeant fluorescent dye, a hydroxyl regioisomeric 3'',4''-benzorhodol, which can be used as a fluorescent chemosensor and biomarker for biological applications.
Definition
ChEBI: Naphthalene-1,4-diol is a naphthalenediol and a naphthohydroquinone.
Biological Activity
1,4-Dihydroxynaphthalene is a potent HSV-1 protease inhibitor with inhibitory effects on the HCMV protease, which can be used to study herpesviruses.
References
[1] LAURIE S. TSURUDA A. D J Michael W Lamé. Formation of epoxide and quinone protein adducts in B6C3F1 mice treated with naphthalene, sulfate conjugate of 1,4-dihydroxynaphthalene and 1,4-naphthoquinone[J]. Archives of Toxicology, 1995, 69 6: 362-367. DOI:10.1007/s002040050185.
1,4-Dihydroxynaphthalene Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 | info@afinechem.com | China | 15083 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| Changzhou Anxuan Chemical Co., Ltd | +86-0519-89882563 +86-18961279162 | andy@anxuanchem.com | China | 4327 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
View Lastest Price from 1,4-Dihydroxynaphthalene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-26 | 1,4-Dihydroxynaphthalene
571-60-8
|
$31.00 | 97.10% | 10g | TargetMol Chemicals Inc. | ||
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2025-09-25 | 1,4-Dihydroxynaphthalene
571-60-8
|
$2.00-10.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
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2020-01-01 | 1,4-Dihydroxynaphthalene
571-60-8
|
$1.00 | 1KG | 95-99% | 1ton | Career Henan Chemical Co |
-

- 1,4-Dihydroxynaphthalene
571-60-8
- $31.00
- 97.10%
- TargetMol Chemicals Inc.
-

- 1,4-Dihydroxynaphthalene
571-60-8
- $2.00-10.00
- 99%
- Henan Fengda Chemical Co., Ltd
-

- 1,4-Dihydroxynaphthalene
571-60-8
- $1.00
- 95-99%
- Career Henan Chemical Co
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