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Ammonium thioglycolate

Ammonium thioglycolate
Ammonium thioglycolate structure
CAS No.
5421-46-5
Chemical Name:
Ammonium thioglycolate
Synonyms
ATG;usafmo-2;Perm salt;thiofacoa-50;Hair waving agent;(ca. 60% in Water);Ammoniumthioglykolat;AMMONIUM THIOGLYCOLATE;AMMONIUM THIOGLYCOLLATE;ammonium marcaptoacetate
CBNumber:
CB5445341
Molecular Formula:
C2H7NO2S
Formula Weight:
109.15
MOL File:
5421-46-5.mol

Ammonium thioglycolate Properties

Melting point:
139-139.5 °C
Density 
1.22
form 
Solution
Specific Gravity
1.245 (25℃)
color 
Clear colorless
Odor
strong skunk-like odor
Water Solubility 
Miscible
InChIKey
JYAVWXRMOOCSOD-UHFFFAOYSA-N
CAS DataBase Reference
5421-46-5(CAS DataBase Reference)
EWG's Food Scores
2-4
FDA UNII
6P9E788VZZ
EPA Substance Registry System
Acetic acid, 2-mercapto-, ammonium salt (1:1) (5421-46-5)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS05,GHS06,GHS07
Signal word  Danger
Hazard statements  H402-H290-H301-H317
Precautionary statements  P234-P261-P264-P270-P272-P273-P301+P310+P330-P302+P352+P333+P313+P363-P390-P405-P406-P501-P280-P301+P310
Hazard Codes  T
Risk Statements  25-43
Safety Statements  36/37-45-37-24
RIDADR  2810
WGK Germany  1
RTECS  AI7525000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29309090
Toxicity LD50 ipr-rat: 165 mg/kg JPETAB 97,349,49
NFPA 704
0
2 0

Ammonium thioglycolate price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 10010 Ammonium thioglycolate solution ~60% in H2O 5421-46-5 1l $70.2 2021-03-22 Buy
TCI Chemical A2217 Ammonium Thioglycolate (ca. 60% in Water) 5421-46-5 25g $16 2021-03-22 Buy
TCI Chemical A2217 Ammonium Thioglycolate (ca. 60% in Water) 5421-46-5 500g $30 2021-03-22 Buy

Ammonium thioglycolate Chemical Properties,Uses,Production

Description

Ammonium thioglycolate, also known as perm salt, is the chemical compound with the formula HSCH2CO2NH4. Being the salt of a weak acid and weak base, ammonium thioglycolic acid exists in solution as an equilibrium mixture of the salt itself as well as the free carboxylic acid thioglycolic acid (HSCH2CO2H) and ammonia : HSCH2COO- + NH4+ ? HSCH2COOH + NH3.

Chemical Properties

Clear colorless solution with characteristic odor

Uses

acts as a reducing agent in permanent-waving formulations for hair treatment and in shrink-resistant treatment of wool.

Uses

Ammonium thioglycolate is contained in permanent waves solutions and causes contact dermatitis in hairdressers.

Uses

Solutions of various strengths are used for hair waving and for hair removal.

General Description

Colorless to faint pink liquid with a repulsive, skunk-like odor.

Air & Water Reactions

Water soluble.

Reactivity Profile

Ammonium thioglycolate may be sensitive to heat. Ammonium thioglycolate is incompatible with acids.

Fire Hazard

Flash point data for Ammonium thioglycolate are not available. Ammonium thioglycolate is combustible.

Contact allergens

This substance is contained in “basic” permanent waves solutions and causes contact dermatitis in hairdressers.

Safety Profile

Poison by intravenous and intraperitoneal routes. An allergen; can cause contact dermatitis. Emits hydrogen sulfide. See also SULFIDES. When heated to decomposition it emits very toxic NOx, SOx, and NH3.

Chemical concepts related to perms

When discussing the chemistry of perms, one should consider two chemical facts. First is the thiol-disulfide equilibrium:
RSH + R'SSR' ? R'SH + RSSR'
where R and R' are organic substituents such as methyl (-CH3), ethyl (-C2H5), or -CH2COO-.
The thiol-disulfide exchange reaction is accelerated by bases such as ammonia, because the base generates some thiolate anion (RS- ), which attacks the disulfide. Thus the ammonia plays multiple roles (and more, see below) in this application.
The second chemical fact is that polar molecules are less volatile than nonpolar ones. So the glycolate substituent makes the thiol nonvolatile and hence non-odorous. An added advantage is that the glycolate confers some solubility in water. One could almost certainly use HSCH3 and ammonia to give a perm, but there would be serious olfactory consequences.

The actual chemistry of perms

A solution containing ammonium thioglycolate contains a lot of free ammonia, which swells hair, rendering it permeable. The thioglycolic acid in the perm solution reduces the disulfide cystine bonds in the cortex of the hair. In a sense, the thioglycolate removes crosslinks. After washing, the hair is treated with a mild solution of hydrogen peroxide, which oxidizes the cysteines back to cystine. These new chemical bonds impart the structural rigidity necessary for a successful perm. The rigidification process is akin to the vulcanization of rubber, where commonly polysulfide linkages are used to crosslink the polymer chains. However, not as many disulfide bonds are reformed as there were before the permanent. As a result, the hair is weaker than before the permanent was applied and repeated applications over the same spot may eventually cause strand breakage.

Ammonium thioglycolate Preparation Products And Raw materials

Raw materials

Preparation Products


Ammonium thioglycolate Suppliers

Global( 140)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 8882 55
Shanxi Naipu Import and Export Co.,Ltd
+8613734021967
kaia@neputrading.com CHINA 1010 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29960 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
+86 0531-67809011 sales@sdzschem.com CHINA 2858 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282
sales3@crovellbio.com China 5460 58
Chongqing Chemdad Co.,Ltd
+86-19923101450
sales@chemdad.com CHINA 4000 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 linda@hubeijusheng.com CHINA 23035 58
Shandong chuangyingchemical Co., Ltd.
18853181302
sale@chuangyingchem.com CHINA 5917 58
Shanghai Longyu Biotechnology Co., Ltd.
+8615821988213
info@longyupharma.com CHINA 2462 58

View Lastest Price from Ammonium thioglycolate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-10-12 Ammonium Thioglycolate
5421-46-5
US $100.00 / KG 1KG 99 5tons Shanxi Naipu Import and Export Co.,Ltd
2021-09-07 Ammonium thioglycolate
5421-46-5
US $0.00 / Kg/Drum 1KG 99.9% 100000kg per month Wuhan Mulei New Material Technology Co. Ltd
2019-07-06 Ammonium thioglycolate
5421-46-5
US $1.00 / kg 1kg 98% as request career henan chemical co

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