ChemicalBook
Chinese Japanese Germany Korea

Miconazole

Miconazole
Miconazole structure
CAS No.
22916-47-8
Chemical Name:
Miconazole
Synonyms
r18134;mjr1762;R 18134;Minostate;Miconazol;micronazol;MICONAZOLE;NSC 170986;Miconozole;MONISTAT IV
CBNumber:
CB6493824
Molecular Formula:
C18H14Cl4N2O
Formula Weight:
416.13
MOL File:
22916-47-8.mol

Miconazole Properties

Melting point:
159-163C
Boiling point:
555.1±50.0 °C(Predicted)
Density 
1.5326 (rough estimate)
refractive index 
1.6200 (estimate)
RTECS 
NI4770000
Flash point:
87°(189°F)
solubility 
Very slightly soluble in water, freely soluble in methanol, soluble in ethanol (96 per cent).
form 
neat
pka
pKa 6.91(H2O,t =25) (Uncertain)
Water Solubility 
Freely soluble in alcohols or acetone. Also soluble in DMF or chloroform. Insoluble in water
Sensitive 
Light Sensitive
CAS DataBase Reference
22916-47-8(CAS DataBase Reference)
NIST Chemistry Reference
Miconazole(22916-47-8)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H413-H227-H317
Precautionary statements  P210e-P280a-P370+P378a-P403+P235-P301+P312+P330-P261-P280g-P301+P312a-P321-P333+P313-P501a
Hazard Codes  Xn
Risk Statements  22
Safety Statements  22-36
RIDADR  3249
WGK Germany  3
HazardClass  6.1(b)
PackingGroup  III
HS Code  2933290000

Miconazole price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR1618 Miconazole 22916-47-8 1g $76.7 2018-11-20 Buy
Sigma-Aldrich 1443409 Miconazole 22916-47-8 200mg $352.8 2018-11-20 Buy
Alfa Aesar J60872 Miconazole, 99% 22916-47-8 5g $42.6 2018-11-13 Buy
Alfa Aesar J60872 Miconazole, 99% 22916-47-8 1g $15.5 2018-11-13 Buy
Sigma-Aldrich M1880000 Miconazole European Pharmacopoeia (EP) Reference Standard 22916-47-8 m1880000 $179 2018-11-23 Buy

Miconazole Chemical Properties,Uses,Production

Chemical Properties

White or almost white powder.

Uses

Antifungal;Sterol 14-demethylase inhibitor

Indications

Miconazole (Monistat) is a broad-spectrum imidazole antifungal agent used in the topical treatment of cutaneous dermatophyte infections and mucous membrane Candida infections, such as vaginitis. Minimal absorption occurs from skin or mucous membrane surfaces. Local irritation to skin and mucous membranes can occur with topical use; headaches, urticaria, and abdominal cramping have been reported with treatment for vaginitis.

brand name

M-Zole (Actavis); Monistat (Ortho-McNeil); Monistat (Personal Products); Monistat (Johnson & Johnson).

Veterinary Drugs and Treatments

Miconazole is a broad spectrum imidazole antifungal agent with some antibacterial activity. Miconazole will penetrate the intact corneal epithelium. Topical miconazole therapy has been a favorite first choice agent for treatment of fungal keratitis in the horse by veterinary ophthalmologists for several years. Miconazole may be delivered by subconjunctival route, but with some local irritation, and topical use is the most commonly employed treatment method.

Veterinary Drugs and Treatments

Topical miconazole has activity against dermatophytes and yeasts; miconazole shampoos can be effective treatment for Malassezia dermatitis. Patients with severe, generalized infections may require systemic therapy. Lotions, sprays and creams are generally used for localized lesions associated with Malassezia or dermatophytes. See otic section for information on application for Malassezia otitis externa.
Topical miconazole products are generally ineffective (or minimally effective) when used alone for dermatophytosis; adjunctive systemic treatment is usually required.
Miconazole’s actions are a result of altering permeability of fungal cellular membranes and interfering with peroxisomal and mitochondrial enzymes, leading to intracellular necrosis. Miconazole products are fungicidal with repeated application.

Miconazole Preparation Products And Raw materials

Raw materials

Preparation Products


Miconazole Suppliers

Global( 154)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21671 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sale@mainchem.com CHINA 32447 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1861 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30001 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 8918 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8407 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6372 58

View Lastest Price from Miconazole manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-23 Miconazole
22916-47-8
US $1.00 / kg 1kg 98%min as request career henan chemical co

22916-47-8(Miconazole)Related Search:


Copyright 2017 © ChemicalBook. All rights reserved