ChemicalBook >> CAS DataBase List >>4-Methyl-1-piperazineethanamine

4-Methyl-1-piperazineethanamine

CAS No.
934-98-5
Chemical Name:
4-Methyl-1-piperazineethanamine
Synonyms
2-(4-METHYLPIPERAZIN-1-YL)ETHANAMINE;AKOS BB-6128;CHEMBRDG-BB 4006383;4-Methylpiperazin-1-ethylamin;4-METHYL-1-PIPERAZINEETHANAMINE;4-methylpiperazine-1-ethylamine;1-(2-AMINOETHYL)METHYLPIPERAZINE;1-Piperazineethanamine, 4-methyl-;1-(2-Aminoethyl)-4-methyl-piperaz;1-Methyl-4-(2-aminoethyl)piperazine
CBNumber:
CB6721134
Molecular Formula:
C7H17N3
Molecular Weight:
143.23
MDL Number:
MFCD03701701
MOL File:
934-98-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:59:19
Product description Number Pack Size Price
2-(4-Methyl-piperazin-1-yl)-ethylamine AldrichCPR CDS003000 250MG $93.2
2-(4-Methylpiperazin-1-yl)ethan-1-amine min. 95.0 % M3597 1G $55
2-(4-Methylpiperazin-1-yl)ethanamine M725980 2.5g $130
1-(2-Aminoethyl)-4-methylpiperazine 95% OR0800 5g $106
2-(4-Methyl-piperazin-1-yl)-ethylamine 97% 008504 5g $85
More product size

4-Methyl-1-piperazineethanamine Properties

Boiling point 103°C/11.25mm
Density 0.956±0.06 g/cm3(Predicted)
refractive index 1.4780
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form liquid
pka 10.11±0.10(Predicted)
color Colourless to light yellow
Sensitive Air Sensitive
InChI InChI=1S/C7H17N3/c1-9-4-6-10(3-2-8)7-5-9/h2-8H2,1H3
InChIKey GOWUDHPKGOIDIX-UHFFFAOYSA-N
SMILES N1(CCN)CCN(C)CC1
CAS DataBase Reference 934-98-5(CAS DataBase Reference)
FDA UNII Z79BOY08I2
UNSPSC Code 12352116
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22
Safety Statements  26-36/37/39
RIDADR  2735
WGK Germany  WGK 3
Hazard Note  Irritant
HazardClass  8
PackingGroup 
HS Code  29339900
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
0
3 0

4-Methyl-1-piperazineethanamine price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich CDS003000 2-(4-Methyl-piperazin-1-yl)-ethylamine AldrichCPR 934-98-5 250MG $93.2 2026-04-30 Buy
TCI Chemical M3597 2-(4-Methylpiperazin-1-yl)ethan-1-amine min. 95.0 % 934-98-5 1G $55 2026-04-30 Buy
TRC M725980 2-(4-Methylpiperazin-1-yl)ethanamine 934-98-5 2.5g $130 2021-12-16 Buy
Apolloscientific OR0800 1-(2-Aminoethyl)-4-methylpiperazine 95% 934-98-5 5g $106 2021-12-16 Buy
Matrix Scientific 008504 2-(4-Methyl-piperazin-1-yl)-ethylamine 97% 934-98-5 5g $85 2021-12-16 Buy
Product number Packaging Price Buy
CDS003000 250MG $93.2 Buy
M3597 1G $55 Buy
M725980 2.5g $130 Buy
OR0800 5g $106 Buy
008504 5g $85 Buy

4-Methyl-1-piperazineethanamine Chemical Properties,Uses,Production

Uses

2-(4-Methylpiperazin-1-yl)ethanamine (cas# 934-98-5) is a useful research chemical.

Chemical Properties

Colorless liquid

Uses

1-(2-Aminoethyl)-4-methylpiperazine is used as pharmaceutical intermediate.

Definition

ChEBI: A N-alkylpiperazine that is piperazine substituted by a methyl and a 2-aminoethyl group at the N atoms respectively.

Synthesis

1-(4-METHYLPIPERAZINE)ACETONITRILE

874-77-1

4-Methyl-1-piperazineethanamine

934-98-5

Step 5. To a stirred suspension of lithium aluminum hydride (3.3 g, 87 mmol) in anhydrous THF (100 mL) was slowly added a solution of 2-(4-methylpiperazin-1-yl)acetonitrile (11.2 g, 80.4 mmol) in anhydrous THF (300 mL) at 0 °C. The reaction mixture was stirred at room temperature for 1 hour. Subsequently, the mixture was cooled in an ice bath and H2O (3.3 mL) and 20% NaOH solution (3.3 mL) were added sequentially. After stirring for 20 minutes, the mixture was filtered and the solvent was evaporated. The residue was dissolved in ethyl acetate and dried with anhydrous sodium sulfate. The solvent was evaporated to dryness to give 2-(4-methylpiperazin-1-yl)ethylamine as an oil (1.15 g, 99%).1H NMR (400 MHz, CDCl3) δ: 2.21 (s, 3H), 2.20-2.60 (m, 10H), 2.71 (t, J=6.0 Hz, 2H).

References

[1] Journal of Medicinal Chemistry, 1999, vol. 42, # 15, p. 2870 - 2880
[2] Patent: WO2013/148365, 2013, A1. Location in patent: Paragraph 0086
[3] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 7, p. 2251 - 2259
[4] Patent: WO2016/16728, 2016, A2. Location in patent: Paragraph 000703; 000704
[5] Patent: WO2005/35532, 2005, A1. Location in patent: Page/Page column 30

4489-39-8
934-98-5
Synthesis of 4-Methyl-1-piperazineethanamine from 1H-Isoindole-1,3(2H)-dione, 2-[2-(4-methyl-1-piperazinyl)ethyl]-
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View Lastest Price from 4-Methyl-1-piperazineethanamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Methyl-1-piperazineethanamine pictures 2022-01-04 4-Methyl-1-piperazineethanamine
934-98-5
US $0.00-0.00 / KG 1g 99%minGC 1ton/month Shanghai Rlavie Technology Co ltd
4-Methyl-1-piperazineethanamine pictures 2019-07-06 4-Methyl-1-piperazineethanamine
934-98-5
US $1.00 / KG 1KG 90%-99.99% 500kgs Career Henan Chemical Co
AKOS BB-6128 4-METHYL-1-PIPERAZINEETHANAMINE 1-(2-AMINOETHYL)-4-METHYL-PIPERAZINE 2-(4-METHYL-PIPERAZIN-1-YL)-ETHYLAMINE 1-(N-AMINOETHYL)-4-METHYL PIPERAZINE CHEMBRDG-BB 4006383 4-methylpiperazine-1-ethylamine 1-(2-AMINOETHYL)METHYLPIPERAZINE 2-(4-Methyl-piperazin-1-yl)-ethylamine ,98% 1-Methyl-4-(2-aminoethyl)piperazine 2-(4-methylpiperazin-1-yl)ethanamine(SALTDATA: FREE) 2-(4-Methylpiperazin-1-yl)ethylamine, 1-Amino-2-(4-methylpiperazin-1-yl)ethane 1-(2-Aminoethyl)-4-methylpiperazine 98+% 1-(2-AMinoethyl)-4-Methylpiperazine, 97+% 1-Piperazineethanamine, 4-methyl- 2-(4-methyl-1-piperazinyl)ethanamine N'-(benzenesulfonyl)-N'-prop-2-enylbenzohydrazide 1-(2-Aminoethyl)-4-methylpiperazine 95% 2-(4-Methyl-1-piperazinyl)ethylamine 4-Methylpiperazin-1-ethylamin 1-(2-Aminoethyl)-4-methyl-piperaz 2-(4-METHYLPIPERAZIN-1-YL)ETHANAMINE 934-98-5 C7H17N3 Piperaizine piperazines