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Description References
Lornoxicam structure
Chemical Name:
Xefo;Telos;TS 110;Xefocam;AKOS 93662;LORNOXICAM;Ro 13-9297;LornoxicaM API;chlortenoxicam;LornoxicaM (Xefo)
Molecular Formula:
Formula Weight:
MOL File:

Lornoxicam Properties

Melting point:
225-230°C (dec.)
storage temp. 
-20°C Freezer
DMSO: >5mg/mL (warmed)
pKa2 4.7(at 25℃)
faint yellow to dark yellow
CAS DataBase Reference
70374-39-9(CAS DataBase Reference)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi,T+
Risk Statements  36/37/38-28
Safety Statements  26-36-45-36/37-28
RIDADR  UN 2811 6.1 / PGII
WGK Germany  3
RTECS  XJ9095000
HazardClass  IRRITANT
PackingGroup  II
HS Code  29349990
Toxicity LD50 orally in mice, rats, rabbits, dogs, monkeys: >10 mg/kg (Pruss)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405 Store locked up.
P501 Dispose of contents/container to..…

Lornoxicam price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0338 Lornoxicam ≥98% (HPLC) 70374-39-9 10mg $75.2 2018-11-20 Buy
Sigma-Aldrich SML0338 Lornoxicam ≥98% (HPLC) 70374-39-9 50mg $305 2018-11-20 Buy
TCI Chemical L0239 Lornoxicam >98.0%(HPLC)(N) 70374-39-9 1g $141 2018-11-22 Buy
TCI Chemical L0239 Lornoxicam >98.0%(HPLC)(N) 70374-39-9 5g $432 2018-11-22 Buy
Cayman Chemical 70220 Lornoxicam ≥98% 70374-39-9 50mg $45 2018-11-13 Buy

Lornoxicam Chemical Properties,Uses,Production


Lornoxicam (Trade name: “Xefo”) belongs to a non-steroidal anti-inflammatory drug. As a kind of oxicam class drug, it has analgesic, anti-inflammatory and antipyretic properties. It can be used for the treatment of various type of acute mild to moderate pain which results from inflammatory diseases of the joints, osteoarthritis, surgery, sciatica and rheumatic diseases. Lornoxicam is capable of potently inhibiting the prostaglandin biosynthesis process, making it have highly pronounced efficacy. The exact mechanism of Lornoxicam is not exactly understood. However, it is indicated that Lornoxicam can inhibit the prostaglandin and thromboxane synthesis by inhibiting both COX-1 and COX-2, leading to reduction of inflammation, pain, fever, and swelling.



Xefo, a member of the oxicam family of nonsteroidal antiinflammatory agents, was launched in Denmark for mild to moderate pain and inflammation. A seven step synthesis, beginning with 2,5-dichlorothiophene, provides access to this compound. It inhibits prostaglandin synthesis at the level of cyclooxygenase (Cox1 :Cox2 = 0.6) but does not inhibit 5-lipoxygenase. Xefo did not increase serum levels of pepsinogen I (an indicator of gastric mucosal status) and readily penetrates perivascular interstitial spaces including synovial fluid. It is as effective as morphine, meperidine and tramadol in relieving post operative pain and as efficient as other NSAlDs in relieving the symptoms of osteoarthritis and rheumatoid arthritis. It is 100 times more potent than Tenoxicam in inhibiting PGD2 and more active than indomethacin (6x) or piroxicam (10x) in preventing arachadonic acid influenced lethality in mice. Xefo has inhibitor effects on spinal nocicceptive processing presumably via release of endogenous opiods and evidence suggests it is good for migraine.

Chemical Properties

Crystalline Solid


Nycomed Amersham (Norway)


Cyclooxygenase inhibitor; structurally similar to tenoxicam. Anti-inflammatory; analgesic


keratolytic, antiacne, antineoplastic


ocular vasoconstrictor


For the treatment of acute mild to moderate pain, as well as pain and inflammation of the joints caused by certain types of rheumatic diseases.


ChEBI: A thienothiazine-derived monocarboxylic acid amide obtained by formal condensation of the carboxy group of 6-chloro-4-hydroxy-2-methylthieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide with the amino group of 2-aminopyridine. Used for th treatment of pain, primarily resulting from inflammatory diseases of the joints, osteoarthritis, surgery, sciatica and other inflammations.

brand name


Lornoxicam Preparation Products And Raw materials

Raw materials

Preparation Products

Lornoxicam Suppliers

Global( 230)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 21954 58
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 CHINA 1530 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32457 55
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 24001 58
Casorganics US Corp
+17326109938 CHINA 141 58
career henan chemical co
+86-371-86658258 CHINA 20331 58
Chongqing Landtower Pharmaceutical Co., Ltd. 023-68980308
023-68980318 China 37 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96519 76

View Lastest Price from Lornoxicam manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-20 Lornoxicam
US $1.00 / KG 1G 98% 100KG career henan chemical co

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