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Clindamycin phosphate

Clindamycin phosphate
Clindamycin phosphate structure
CAS No.
24729-96-2
Chemical Name:
Clindamycin phosphate
Synonyms
u28508;U-28508E;Clindets;dalacinp;Cleocin T;Dalacin T;NSC 618653;(2s-trans)-;cleocinphosphate;ANTIBIOTIC U-28508E
CBNumber:
CB8175076
Molecular Formula:
C18H34ClN2O8PS
Formula Weight:
504.97
MOL File:
24729-96-2.mol

Clindamycin phosphate Properties

Melting point:
114 °C
Boiling point:
159°C
refractive index 
122 ° (C=1, H2O)
storage temp. 
2-8°C
solubility 
DMSO: soluble224mg/mL at 25°C
form 
solid
pka
pKa 0.964±0.06 (H2O t=21) (Uncertain);6.06 ±0.06 (I=0.008)(H2O t=21) (Uncertain)
Water Solubility 
Freely soluble in water
Merck 
14,2356
Stability:
Stable, but store cool. Incompatible with strong oxidizing agents, calcium gluconate, barbiturates, magnesium sulfate, phenytoin, B group sodium vitamins.
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  36-26
WGK Germany  3
RTECS  GF2625000
HS Code  29419000
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Clindamycin phosphate price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C6427 Clindamycin 2-phosphate aminoglycoside antibiotic 24729-96-2 50mg $170 2018-11-20 Buy
Sigma-Aldrich C6427 Clindamycin 2-phosphate aminoglycoside antibiotic 24729-96-2 100mg $293 2018-11-20 Buy
TCI Chemical C2257 Clindamycin Phosphate >97.0%(T) 24729-96-2 5g $106 2018-11-22 Buy
TCI Chemical C2257 Clindamycin Phosphate >97.0%(T) 24729-96-2 25g $320 2018-11-22 Buy
Alfa Aesar J63387 Clindamycin phosphate 24729-96-2 100mg $248 2018-11-13 Buy

Clindamycin phosphate Chemical Properties,Uses,Production

Chemical Properties

solid

Uses

Lincosamide antibacterial.

Uses

Clindamycin (C580000) impurity in bulk drug.

Uses

A highly water soluble Clindamycin prodrug.

Uses

Clindamycin 2-phosphate is a a salt of clincamycin, a semi-synthetic lincosamide. The salt is prepared by selective phosphorylation of the 2-hydroxy moiety of the sugar of clindamycin. The introduction of the phosphate affords improved solubility for injectable formulations. Like other members of the lincosamide family, clindamycin 2-phosphate is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Clindamycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis.

Uses

Clindamycin 2-phosphate is a salt of clindamycin, a semi-synthetic lincosamide. The salt is prepared by selective phosphorylation of the 2-hydroxy moiety of the sugar of clindamycin. The introduction of the phosphate affords improved solubility for injectable formulations. Like other members of the lincosamide family, clindamycin 2-phosphate is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Clindamycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis.

General Description

Clindamycin phosphate (Cleocin Phosphate) is the 2-phosphateester of clindamycin. It exists as a zwitterionic structurethat is very soluble in water. It is intended for parenteral(intravenous or intramuscular) administration for the treatmentof serious infections and instances when oral administrationis not feasible. Solutions of clindamycin phosphateare stable at room temperature for 16 days and for up to 32days when refrigerated.

Contact allergens

This lincosanide antibiotic is used in topical form for acne, or systemically has been responsible for exanthematous rashes and acute generalized exanthematous pustulosis.

Clindamycin phosphate Preparation Products And Raw materials

Raw materials

Preparation Products


Clindamycin phosphate Suppliers

Global( 276)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21968 58
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 sales01@cooperate-pharm.com CHINA 1530 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20680 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com CHINA 1367 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
PI & PI BIOTECH INC.
020-81716320
020-81716319 Sales@pipitech.com CHINA 2543 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1730 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114
sales@amoychem.com CHINA 6374 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24001 58

View Lastest Price from Clindamycin phosphate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-04-03 Clindamycin phosphate in stock Factory
24729-96-2
US $1.00 / KG 1KG TOP 3 Factory in China Top 3 production capacity Factory Chemwill Asia Co.,Ltd.
2018-08-20 Clindamycin phosphate
24729-96-2
US $1.00 / KG 1G 98% 100KG career henan chemical co
2018-07-26 Clindamycin phosphate
24729-96-2
US $100.00 / KG 1KG 99% Customized career henan chemical co

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