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PD168393
- CAS No.
- 194423-15-9
- Chemical Name:
- PD168393
- Synonyms
- CS-2316;PD 168393;PD168393 USP/EP/BP;PD-168393;PD 168393;PD168393;PD-168393;PD 168393;4-[(3-BROMOPHENYL)AMINO]-6-ACRYLAMIDOQUINAZOLINE;N-[4-(3-Bromoanilino)quinazolin-6-yl]prop-2-enamide;N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide;N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-propenamide;2-Propenamide, N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-
- CBNumber:
- CB8316129
- Molecular Formula:
- C17H13BrN4O
- Molecular Weight:
- 369.22
- MDL Number:
- MFCD02179207
- MOL File:
- Mol file
- MSDS File:
- SDS
Last updated:2023-09-04 15:51:00
Melting point | 279℃ |
---|---|
Boiling point | 571.1±50.0 °C(Predicted) |
Density | 1.558±0.06 g/cm3(Predicted) |
storage temp. | room temp |
solubility | insoluble in H2O; ≥1 mg/mL in EtOH with gentle warming and ultrasonic; ≥18.45 mg/mL in DMSO |
form | powder |
pka | 12.19±0.43(Predicted) |
color | white to beige |
FDA UNII | 3R996Y9T0I |
PD168393 price More Price(33)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 513033 | PD 168393 - CAS 194423-15-9 - Calbiochem | 194423-15-9 | 1mg | $201 | 2024-03-01 | Buy |
Sigma-Aldrich | PZ0285 | PD168393 ≥98% (HPLC) | 194423-15-9 | 5MG | $115 | 2023-06-20 | Buy |
Sigma-Aldrich | PZ0285 | PD168393 ≥98% (HPLC) | 194423-15-9 | 25MG | $451 | 2023-06-20 | Buy |
Cayman Chemical | 21059 | PD 168393 ≥95% | 194423-15-9 | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 21059 | PD 168393 ≥95% | 194423-15-9 | 5mg | $100 | 2024-03-01 | Buy |
PD168393 Chemical Properties,Uses,Production
Uses
PD 168393, is an irreversible epidermal growth factor receptor (EGFR) inhibitor.
Uses
PD168393 has been used in the acute inhibition of ErbB4.
Definition
ChEBI: A member of the class of quinazolines carrying bromoanilino and acrylamido substituents at positions 4 and 6 respectively.
Biochem/physiol Actions
PD168393 is a 6-acrylamido-4-anilinoquinazoline compound. It increases apoptosis in malignant peripheral nerve sheath tumor cells, stimulated by lysosomal dysfunction.
target
EGFR
PD168393 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 131)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
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InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
194423-15-9(PD168393)Related Search:
4-[(3-BROMOPHENYL)AMINO]-6-ACRYLAMIDOQUINAZOLINE
PD 168393
N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-propenamide
2-Propenamide, N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-
N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide
PD168393;PD-168393;PD 168393
CS-2316
N-[4-(3-Bromoanilino)quinazolin-6-yl]prop-2-enamide
PD-168393;PD 168393
PD168393 USP/EP/BP
194423-15-9
Inhibitors