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5-Nitrobenzimidazole

5-Nitrobenzimidazole structure

CAS No.: 94-52-0

Chemical Name:: 5-Nitrobenzimidazole

Synonyms: 6-NITROBENZIMIDAZOLE;5-NITRO-1H-BENZIMIDAZOLE;5-NITRO-1H-BENZO[D]IMIDAZOLE;nci-c01912;BIO-FARMA BF002407;6-nitrobenzimdazole;6-nitro-benzimidazo;5-Nrtiobenzimidazole;5-nitro-benzimidazol;6-nitro-benzimidazol

CBNumber:: CB8697293

Molecular Formula:: C7H5N3O2

Molecular Weight:: 163.13

MDL Number:: MFCD00005604

MOL File:: 94-52-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:08:12

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5-Nitrobenzimidazole Properties

Melting point	207-210 °C
Boiling point	290.19°C (rough estimate)
Density	1.4141 (rough estimate)
bulk density	270kg/m3
refractive index	1.5500 (estimate)
storage temp.	Store below +30°C.
solubility	0.5g/l
pka	10.95±0.10(Predicted)
form	Solid
color	Light Beige
PH	6 (10g/l, H2O, 20℃)(slurry)
Water Solubility	<0.01 g/100 mL at 16.5 ºC
BRN	7926
Henry's Law Constant	2.7×10¹ mol/(m³Pa) at 25℃, HSDB (2015)
Stability	Stable. Combustible. Incompatible with strong oxidizing agents, strong bases.
InChI	1S/C7H5N3O2/c11-10(12)5-1-2-6-7(3-5)9-4-8-6/h1-4H,(H,8,9)
InChIKey	XPAZGLFMMUODDK-UHFFFAOYSA-N
SMILES	[N+](=O)([O-])c1cc2[nH]cnc2cc1
Toxicology and Carcinogenesis	Bioassay of 6-Nitrobenzimidazole for Possible Carcinogenicity (CASRN 94-52-0)
CAS DataBase Reference	94-52-0(CAS DataBase Reference)
FDA UNII	A7V95AYT2T
EPA Substance Registry System	5-Nitrobenzimidazole (94-52-0)
UNSPSC Code	12352102
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-40-22

Safety Statements

26-45-36/37

RIDADR

2811

WGK Germany

RTECS

DD9800000

TSCA

TSCA listed

HS Code

29339990

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

Hazardous Substances Data

94-52-0(Hazardous Substances Data)

NFPA 704

	1
2		0

5-Nitrobenzimidazole price More Price(46)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	S763799	6-NITROBENZIMIDAZOLE Aldrich^CPR	94-52-0	1 unit	$197	2026-04-30	Buy
Sigma-Aldrich	8.18257	5-Nitrobenzimidazole for synthesis	94-52-0	100g	$127	2026-04-30	Buy
Sigma-Aldrich	S763799	6-NITROBENZIMIDAZOLE Aldrich	94-52-0	50mg	$179	2024-03-01	Buy
TCI Chemical	N0152	5-Nitrobenzimidazole >98.0%(GC)(T)	94-52-0	25g	$143	2026-04-30	Buy
TRC	TRC-N494795-1G	5-Nitrobenzimidazole	94-52-0	1g	$73	2026-06-03	Buy

Product number	Packaging	Price	Buy
S763799	1 unit	$197	Buy
8.18257	100g	$127	Buy
S763799	50mg	$179	Buy
N0152	25g	$143	Buy
TRC-N494795-1G	1g	$73	Buy

5-Nitrobenzimidazole Chemical Properties,Uses,Production

Chemical Properties

white or pale yellow powder

Uses

Antifogging agent in photographic developers.

Uses

5-Nitrobenzimidazole acts as a reagent in the synthesis of benzimidazoles derivatives with antibacterial and antifungal activities. It also functions as a reagent in the synthesis of xanthine oxidase, a key enzyme that catalyze xanthine to uric acid causing hyperuricemia in humans.

General Description

Off-white to pale yellow fluffy powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

5-Nitrobenzimidazole is incompatible with strong oxidizing agents and strong bases.

Fire Hazard

Flash point data for 5-Nitrobenzimidazole are not available but 5-Nitrobenzimidazole is probably combustible.

Synthesis

64-18-6

99-56-9

94-52-0

First, 4-nitrophthalimide (1 g) was mixed with formic acid (0.74 mL) in 5N hydrochloric acid (70 mL), stirred and heated to reflux for 24 hours. Upon completion of the reaction, the mixture was cooled to room temperature, neutralized with 10% sodium hydroxide solution and the precipitate was isolated. Subsequently, the precipitate was recrystallized with water and dried to give 5-nitrobenzimidazole (0.69 g) [37].

References

[1] Molecules, 2015, vol. 20, # 8, p. 15206 - 15223
[2] Journal of the Korean Chemical Society, 2010, vol. 54, # 5, p. 589 - 593
[3] Journal of the Chilean Chemical Society, 2012, vol. 57, # 2, p. 1122 - 1125,4
[4] Journal of Medicinal Chemistry, 2015, vol. 58, # 24, p. 9591 - 9600
[5] Journal of the Chemical Society of Pakistan, 2018, vol. 40, # 2, p. 366 - 374

5-Nitrobenzimidazole synthesis

Synthesis of 5-Nitrobenzimidazole from 4-Nitro-o-phenylenediamine and Trimethoxymethane

5-Nitrobenzimidazole Preparation Products And Raw materials

Raw materials

D-glucose Trimethoxymethane Formic acid Carbon dioxide Triethyl orthoformate

N,N-Diethylformamide 2-Methoxyethanol Benzimidazole Oxalic acid 4-Nitro-o-phenylenediamine

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Preparation Products

Pigment Red 176 1H-Benzimidazole,1-methyl-5-nitro-(9CI) 5-Aminobenzimidazole Nsc170648

5-Nitrobenzimidazole Suppliers

Global( 305)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Changzhou Hengda Biotechnology Co., Ltd	0519-0519-85265229 18015028189	sales@hengdabio.net	China	45	55
Nantong Xiaochang Pharmaceutical Trading Co., Ltd.	0513-82104991 15716298942	sales11@btcpharm.com	China	860	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	94607	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
INTATRADE GmbH	+49 3493/605464	sales@intatrade.de	Germany	3563	66
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66

Supplier	Advantage
Changzhou Hengda Biotechnology Co., Ltd	55
Nantong Xiaochang Pharmaceutical Trading Co., Ltd.	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
INTATRADE GmbH	66
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Capot Chemical Co., Ltd	66

View Lastest Price from 5-Nitrobenzimidazole manufacturers

Update time	Product	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-11	5-Nitrobenzimidazole (6-NitrobenziMidazole) 94-52-0	1KG	99%min	2000kg/month	WUHAN FORTUNA CHEMICAL CO., LTD
2025-12-24	5-Nitrobenzimidazole 94-52-0	1KG	99.0%	1000KG	Shaanxi Dideu Medichem Co. Ltd
2025-04-04	5-Nitrobenzimidazole 94-52-0	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

5-Nitrobenzimidazole (6-NitrobenziMidazole)
94-52-0
$0.00
99%min
WUHAN FORTUNA CHEMICAL CO., LTD

5-Nitrobenzimidazole
94-52-0
99.0%
Shaanxi Dideu Medichem Co. Ltd

5-Nitrobenzimidazole
94-52-0
98%
Henan Aochuang Chemical Co.,Ltd.

5-Nitrobenzimidazole Spectrum

5-Nitrobenzimidazole(94-52-0)MS 5-Nitrobenzimidazole(94-52-0)¹HNMR 5-Nitrobenzimidazole(94-52-0)IR1 5-Nitrobenzimidazole(94-52-0)IR2 5-Nitrobenzimidazole(94-52-0)Raman

94-52-0(5-Nitrobenzimidazole)Related Search:

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