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Description Mechanism of Action Precautions Application Dosage Side Effects
Tetracaine structure
Chemical Name:
Molecular Formula:
Formula Weight:
MOL File:

Tetracaine Properties

Melting point:
41.0 to 45.0 °C
Boiling point:
407.59°C (rough estimate)
1.0200 (rough estimate)
refractive index 
1.5800 (estimate)
storage temp. 
pKa 8.33±0.03(H2O t = 20.0 I = 0.10 (KCl)) (Uncertain)
CAS DataBase Reference
94-24-6(CAS DataBase Reference)
NIST Chemistry Reference
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn,Xi
Risk Statements  22-40-42/43-43
Safety Statements  22-36/37
WGK Germany  3
RTECS  DG4725000
HazardClass  6.1
PackingGroup  III
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Tetracaine price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T3812 Tetracaine meets USP testing specifications 94-24-6 5g $79.8 2018-11-20 Buy
Sigma-Aldrich 1649991 Tetracaine United States Pharmacopeia (USP) Reference Standard 94-24-6 50mg $352.8 2018-11-13 Buy
TCI Chemical T2789 Tetracaine >98.0%(GC)(T) 94-24-6 5g $43 2018-11-22 Buy
TCI Chemical T2789 Tetracaine >98.0%(GC)(T) 94-24-6 25g $128 2018-11-22 Buy
Sigma-Aldrich T7383 Tetracaine ≥98% (TLC) 94-24-6 25g $133 2018-11-20 Buy

Tetracaine Chemical Properties,Uses,Production


Tetracaine is a local anesthetic or numbing medicine that is used to numb the throat, eyes, or nose. Normally, the drug is administered before starting a surgery to decrease pain from the procedure. Tetracaine is applied to the eyes 30 minutes before the start of an intravenous and its effects can last up to 15 minutes.

Mechanism of Action

Tetracaine acts by blocking the nerve systems. It does this by blocking the sodium ion channels needed for the conduction and initiation of neural impulses, thereby affecting the local anesthesia. Tetracaine acts by altering the function of calcium release channels that controls the release of calcium frim intracellular cells.


No studies have revealed whether the medicine can affect an unborn child; however, it is important to inform the doctor if pregnant while using it.

Informing the doctor is paramount if breastfeeding a baby, as no known research has illustrated whether tetracaine can pass into breast milk or harm a nursing baby.

To make tetracaine safe, it is important to inform the doctor if one has a history of spinal or brain injury, heart diseases, eye problems, a blood vessel disorder, open sores, skin injury in the area where the medicine will be applied.

Tetracaine should never be orally taken since it is typically designed for use on the skin only. If the medicine gets in the mouth, nose, vagina, or rectum, rinse with water.


Tetracaine topical (for the skin) is used to numb various body parts before a surgical procedure or a medical test. Conversely, tetracaine ophthalmic drops are used as local anesthetic for the eyes.


Always follow all direction on the prescription label. Do not use the medicine in smaller or larger amounts or for longer than recommended.

Side Effects

Seek emergency medical advice in case of any of the following allergic reactions: difficult breathing, hives, swelling of the throat, tongue, lips, or face. Stop using the drug and call the physician if one has severe burning, swelling, stinging, or other irritation of the treated skin. Other alarming symptoms include eye watering, irritation, and increased sensitivity to light.

Common side effects include burning, stinging, or itching at the point of application of the medicine; numbness in places where tetracaine has been accidentally applied or skin redness or tenderness.

Nonclinical Toxicology
Studies conducted to reveal the genotoxicity of tetracaine have not indicated its mutagenesis, carcinogenicity, or impairment of fertility.

Chemical Properties

White or light-yellow, waxy solid. Very slightly soluble in water; soluble in alcohol, ether, benzene, chloroform.




ChEBI: A benzoate ester in which 4-N-butylbenzoic acid and 2-(dimethylamino)ethanol have combined to form the ester bond; a local ester anaesthetic (ester caine) used for surface and spinal anaesthesia.

General Description

Tetracaine was developed to address the low potency andshort duration of action of procaine and chloroprocaine. The addition of the butyl side chain on the para nitrogen increasesthe lipid solubility of the drug and enhances the topical potencyof tetracaine. The plasma half-life is 120 to 150 seconds.Topically applied tetracaine to unbroken skin requires 30 to 45minutes to confer topical anesthesia. Tetracaine 4% gel is superiorthan eutectic mixture with lidocaine (EMLA) (an emulsionof lidocaine and prilocaine) in preventing pain associatedwith needle procedures in children. Tetracaine metabolism issimilar to procaine ester metabolism yielding parabutylaminobenzoicacid and dimethylaminoethanol and conjugatesexcreted in the urine. The pKa of the dimethylated nitrogen is8.4 and tetracaine is formulated as a hydrochloride salt with apH of 3.5 to 6.0. The increased absorption from topical siteshas resulted in reported toxicity. Overdoses of tetracaine mayproduce central nervous system (CNS) toxicity and seizure activitywith fatalities from circulatory depression reported.No selective cardiac toxicity is seen with tetracaine althoughhypotension has been reported. Tetracaine is employed for infiltrationanesthesia, spinal anesthesia, or topical use.

Tetracaine Preparation Products And Raw materials

Raw materials

Preparation Products

Tetracaine Suppliers

Global( 210)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 CHINA 552 55
Hebei Guanlang Biotechnology Co., Ltd.
+86-0311-66562153 whatsapp +8615203118427
+86-0311-66562153 CHINA 416 50
Frapp's ChemicalNFTZ Co., Ltd.
+86 (576) 8169-6106
+86 (576) 8169-6105 China 887 50
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 CHINA 3217 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817 CHINA 22043 58
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 CHINA 1530 55
Shanghai Bojing Chemical Co.,Ltd.
+86-21-37127788 CHINA 500 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32651 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 CHINA 894 55

View Lastest Price from Tetracaine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-04-12 Tetracaine
US $1.00 / g 10g 99% 100000KG Cangzhou Wanyou New Material Technology Co.,Ltd
2019-03-29 Tetracaine
US $100.00 / kg 100g 99.9% 10TONS Hebei Jimi Trading Co., Ltd.
2018-03-05 Tetracaine
US $400.00 / KG 1KG 99.9% 5000KG Hubei XinRunde Chemical Co., Ltd.

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