アロセトロン塩酸塩
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
| 絵表示（GHS） |
|
| 注意喚起語 |
危険 |
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
| H301 |
飲み込むと有毒 |
急性毒性、経口 |
3 |
危険 |
|
P264, P270, P301+P310, P321, P330,P405, P501 |
| H319 |
強い眼刺激 |
眼に対する重篤な損傷性/眼刺激 性 |
2A |
警告 |
 |
P264, P280, P305+P351+P338,P337+P313P |
| H412 |
長期的影響により水生生物に有害 |
水生環境有害性、慢性毒性 |
3 |
|
|
P273, P501 |
|
| 注意書き |
| P273 |
環境への放出を避けること。 |
| P305+P351+P338 |
眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。 |
|
アロセトロン塩酸塩 価格
もっと(6)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TRCA575500 |
アロセトロン塩酸塩
Alosetron Hydrochloride |
122852-69-1 |
50mg |
￥18600 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TRCA575500 |
アロセトロン塩酸塩
Alosetron Hydrochloride |
122852-69-1 |
100mg |
￥21000 |
2024-03-01 |
購入 |
|
東京化成工業
|
A3197 |
アロセトロン塩酸塩 >98.0%(HPLC)
Alosetron Hydrochloride
>98.0%(HPLC) |
122852-69-1 |
100mg |
￥12100 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
SML0346 |
≥98% (HPLC)
Alosetron hydrochloride ≥98% (HPLC) |
122852-69-1 |
10mg |
￥14200 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
SML0346 |
≥98% (HPLC)
Alosetron hydrochloride ≥98% (HPLC) |
122852-69-1 |
50mg |
￥47800 |
2024-03-01 |
購入 |
アロセトロン塩酸塩 化学特性,用途語,生産方法
外観
白色～うすい黄色粉末～結晶
効能
制吐薬, セロトニン5-HT3受容体拮抗薬
説明
Lotronex (alosetron) was developed for the treatment of severe
irritable bowel syndrome (IBS), and was approved for use by
the US Food and Drug Administration (FDA) in 2000.
Although Lotronex had a relatively high improvement rate in
patients taking the drug for IBS, it was voluntarily pulled from
the market by GlaxoWellcome that same year due to reports of
severe adverse side effects, some resulting in death.
In 2002, Lotronex was reapproved in a supplemental New
Drug Application for use under more restrictive conditions.
Now with a risk management program to be consulted prior to
administration of the drug, Lotronex is designated to be
prescribed only when its medical benefits outweigh the risks of
toxic effects; women with severe diarrhea-predominant IBS are
now the focal point of prescriptions for Lotronex.
化学的特性
Alosetron hydrochloride is Crystalline Solid
使用
Alosetron hydrochloride is used in treatment of irritable bowel syndrome
定義
ChEBI: The hydrochloride salt of alosetron.
環境運命予測
The environmental fate and behavior of Lotronex is uncertain,
as formal studies regarding its release into the environment are
virtually nonexistent in the literature. Limited water solubility
(61 mg ml
-1) may lead to persistence in soils, and in sediment
following aquatic release, although specific fates with regard to
degradation, bioaccumulation, and transport are unknown.
アロセトロン塩酸塩 上流と下流の製品情報
原材料
準備製品
アロセトロン塩酸塩 生産企業
Global( 248)Suppliers
アロセトロン塩酸塩 スペクトルデータ(1HNMR)
122852-69-1(アロセトロン塩酸塩)キーワード:
- 122852-69-1
- 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one hydrochloride
- GR 68755C
- 2,3,4,5-tetrahydro-5-methyl-2-[(5-methyl-1h-imidazol-4-yl)methyl]-1h-pyrido[4,3-b]indol-1-one hydrochloride
- ALOSETRON HYDROCHLORIDE
- 2,3,4,5-Tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one Hydrochloride
- GR 68755
- GR 68755X
- Alosetron hydrocloride
- 1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1)
- 5-Methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one Hydrochloride
- Alosetron hydrochloride USP/EP/BP
- Alosetron hydrochlorideQ: What is
Alosetron hydrochloride Q: What is the CAS Number of
Alosetron hydrochloride Q: What is the storage condition of
Alosetron hydrochloride Q: What are the applications of
Alosetron hydrochloride
- ALOSETRON HCL
- Lotronex
- Cc1[nH]cnc1CN2CCc4c(C2=O)c3ccccc3n4C.Cl
- Alosetron hydrochloride salt
- AlosetronHydrochloride/GR68755Hydrochloride
- 5-Methyl-2-((4-methyl-1H-imidazol-5-yl)methyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one hydrochloride
- アロセトロン塩酸塩