アセト酢酸メチル 化学特性,用途語,生産方法
外観
無色～わずかにうすい黄色, 澄明の液体
溶解性
水に可溶 (38g/100ml), エタノールに易溶。エタノール及びアセトンに溶けやすく、水に溶ける。
用途
有機合成原料。
用途
農薬?医薬?染料?顔料原料,溶剤,樹脂安定剤
化学的特性
Colorless, clear liquid
使用
Methyl acetoacetate (MAA) is a starting material for the syntheses of alpha-substituted aceto- acetic esters and cyclic compounds, e.g. pyrazole, pyrimidine and coumarin derivatives.
主な応用
Methyl acetoacetate (MAA) has been used for the following applications:
As a chemical reagent for organic synthesis and as a solvent for cellulose ethers;
As a chemical intermediate for organic compounds, used for the synthesis of nifedipine;
As a food additive, used as an amine protectant for synthetic sweeteners;
As a pharmaceutical raw material, used in the manufacture of antibiotics.
調製方法
Methyl acetoacetate is produced by a reaction of methyl
acetate with sodium methoxide.
一般的な説明
A clear colorless liquid. Flash point 158°F. Denser than water and slightly soluble in water. Vapors heavier than air.
空気と水の反応
Very slightly soluble in water.
反応プロフィール
Methyl acetoacetate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides
危険性
Toxic by ingestion and inhalation.
健康ハザード
May be harmful by inhalation, ingestion, or skin absorption. Causes eye irritation. May cause skin irritation.
安全性プロファイル
Moderately toxic by
ingestion. A skin and severe eye irritant.
Combustible when exposed to heat or
flame. To fight fire, use foam, CO2, dry
chemical. When heated to decomposition it
emits acrid smoke and irritating fumes. See
also ESTERS.
発がん性
Not listed by ACGIH, IARC,
NTP, or California Proposition 65.
アセト酢酸メチル 上流と下流の製品情報
原材料
準備製品