2-クロロ安息香酸 化学特性,用途語,生産方法
外観
白色〜わずかにうすい黄色, 粉末
溶解性
水に難溶。アルコール, エーテル, ベンゼンに可溶。エタノール及びアセトンに溶け、水にほとんど溶けない。
用途
有機合成原料(農薬、医薬、染料)。
説明
2-Chlorobenzoic acid is an organic compound with the formula ClC6H4CO2H. It is one of three isomeric chlorobenzoic acids, the one that is the strongest acid. This white solid is used as a precursor to a variety of drugs, food additives, and dyes.
化学的特性
2-chlorobenzoic acid is a white to pale cream crystals or powder, It is insoluble in water, 95% ethanol solution and toluene solution, soluble in methanol, anhydrous ethanol, ether, acetone and benzene.It is the intermediate of fungicide flubenthrinol, insecticide mirex and bollenuron, and acaricide tetrabenazine.
使用
2-Chlorobenzoic acid was used to study the degradation of 2-bromobenzoic acid by
Pseudomonas aeruginosa.
製造方法
It is prepared by the oxidation of 2-chlorotoluene. The laboratory scale reaction employs potassium permanganate. Alternatively it arises by the hydrolysis of α,α,α-trichloro-2-toluene.
The chloride is readily replaced by ammonia to 2-aminobenzoic acid. At elevated temperature it decarboxylates.
定義
ChEBI: 2-chlorobenzoic acid is a monochlorobenzoic acid having the chloro group at the 2-position. It has a role as a plant hormone and a plant metabolite. It is a monochlorobenzoic acid and a 2-halobenzoic acid. It is a conjugate acid of a 2-chlorobenzoate.
一般的な説明
Crystals or fine fluffy white powder.
空気と水の反応
Insoluble in water.
反応プロフィール
2-Chlorobenzoic acid is incompatible with strong oxidizing agents and strong bases.
火災危険
Flash point data for 2-Chlorobenzoic acid are not available; however, 2-Chlorobenzoic acid is probably combustible.
純化方法
Crystallise the acid successively from glacial acetic acid, aqueous EtOH, and pet ether (b 60-80o). Other solvents include hot water or toluene (ca 4mL/g). The crude material can be initially purified by dissolving 30g in 100mL of hot water containing 10g of Na2CO3, boiling with 5g of charcoal for 15minutes, then filtering and adding 31mL of 1:1 aqueous HCl. The precipitate is washed with a little water and dried at 100o. [Beilstein 9 IV 956.]
2-クロロ安息香酸 上流と下流の製品情報
原材料
準備製品